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Items: 1 to 20 of 24

1.

The Role of mTOR in Neuroendocrine Tumors: Future Cornerstone of a Winning Strategy?

Lamberti G, Brighi N, Maggio I, Manuzzi L, Peterle C, Ambrosini V, Ricci C, Casadei R, Campana D.

Int J Mol Sci. 2018 Mar 6;19(3). pii: E747. doi: 10.3390/ijms19030747. Review.

2.

mTOR Pathways in Cancer and Autophagy.

Paquette M, El-Houjeiri L, Pause A.

Cancers (Basel). 2018 Jan 12;10(1). pii: E18. doi: 10.3390/cancers10010018. Review.

3.

Alcoholic Cardiomyopathy: Disrupted Protein Balance and Impaired Cardiomyocyte Contractility.

Steiner JL, Lang CH.

Alcohol Clin Exp Res. 2017 Aug;41(8):1392-1401. doi: 10.1111/acer.13405. Epub 2017 May 29. Review.

PMID:
28425109
4.

DDiT4L promotes autophagy and inhibits pathological cardiac hypertrophy in response to stress.

Simonson B, Subramanya V, Chan MC, Zhang A, Franchino H, Ottaviano F, Mishra MK, Knight AC, Hunt D, Ghiran I, Khurana TS, Kontaridis MI, Rosenzweig A, Das S.

Sci Signal. 2017 Feb 28;10(468). pii: eaaf5967. doi: 10.1126/scisignal.aaf5967.

5.

Multistep regulation of TFEB by MTORC1.

Vega-Rubin-de-Celis S, Peña-Llopis S, Konda M, Brugarolas J.

Autophagy. 2017 Mar 4;13(3):464-472. doi: 10.1080/15548627.2016.1271514. Epub 2017 Jan 5.

6.

Is REDD1 a Metabolic Éminence Grise?

Lipina C, Hundal HS.

Trends Endocrinol Metab. 2016 Dec;27(12):868-880. doi: 10.1016/j.tem.2016.08.005. Epub 2016 Sep 6. Review.

7.

Emerging role for regulated in development and DNA damage 1 (REDD1) in the regulation of skeletal muscle metabolism.

Gordon BS, Steiner JL, Williamson DL, Lang CH, Kimball SR.

Am J Physiol Endocrinol Metab. 2016 Jul 1;311(1):E157-74. doi: 10.1152/ajpendo.00059.2016. Epub 2016 May 17. Review.

8.

Fibroblast Growth Factor Receptor-Dependent and -Independent Paracrine Signaling by Sunitinib-Resistant Renal Cell Carcinoma.

Tran TA, Leong HS, Pavia-Jimenez A, Fedyshyn S, Yang J, Kucejova B, Sivanand S, Spence P, Xie XJ, Peña-Llopis S, Power N, Brugarolas J.

Mol Cell Biol. 2016 Jun 15;36(13):1836-55. doi: 10.1128/MCB.00189-16. Print 2016 Jul 1.

9.

Iron depletion suppresses mTORC1-directed signalling in intestinal Caco-2 cells via induction of REDD1.

Watson A, Lipina C, McArdle HJ, Taylor PM, Hundal HS.

Cell Signal. 2016 May;28(5):412-424. doi: 10.1016/j.cellsig.2016.01.014. Epub 2016 Jan 29.

10.

RTP801/REDD1: a stress coping regulator that turns into a troublemaker in neurodegenerative disorders.

Canal M, Romaní-Aumedes J, Martín-Flores N, Pérez-Fernández V, Malagelada C.

Front Cell Neurosci. 2014 Oct 2;8:313. doi: 10.3389/fncel.2014.00313. eCollection 2014. Review.

11.

Quantitative Lys-ϵ-Gly-Gly (diGly) proteomics coupled with inducible RNAi reveals ubiquitin-mediated proteolysis of DNA damage-inducible transcript 4 (DDIT4) by the E3 ligase HUWE1.

Thompson JW, Nagel J, Hoving S, Gerrits B, Bauer A, Thomas JR, Kirschner MW, Schirle M, Luchansky SJ.

J Biol Chem. 2014 Oct 17;289(42):28942-55. doi: 10.1074/jbc.M114.573352. Epub 2014 Aug 21.

12.

REDD1 enhances protein phosphatase 2A-mediated dephosphorylation of Akt to repress mTORC1 signaling.

Dennis MD, Coleman CS, Berg A, Jefferson LS, Kimball SR.

Sci Signal. 2014 Jul 22;7(335):ra68. doi: 10.1126/scisignal.2005103. Erratum in: Sci Signal. 2015 Mar 17;8(368):er4.

13.

REDD1/DDIT4-independent mTORC1 inhibition and apoptosis by glucocorticoids in thymocytes.

Wolff NC, McKay RM, Brugarolas J.

Mol Cancer Res. 2014 Jun;12(6):867-77. doi: 10.1158/1541-7786.MCR-13-0625. Epub 2014 Mar 10.

14.

Simultaneous isolation of high-quality DNA, RNA, miRNA and proteins from tissues for genomic applications.

Peña-Llopis S, Brugarolas J.

Nat Protoc. 2013 Nov;8(11):2240-55. doi: 10.1038/nprot.2013.141. Epub 2013 Oct 17.

15.

Platelet-derived growth factor/vascular endothelial growth factor receptor inactivation by sunitinib results in Tsc1/Tsc2-dependent inhibition of TORC1.

Tran TA, Kinch L, Peña-Llopis S, Kockel L, Grishin N, Jiang H, Brugarolas J.

Mol Cell Biol. 2013 Oct;33(19):3762-79. doi: 10.1128/MCB.01570-12. Epub 2013 Jul 22.

16.

Molecular circuit involving KLK4 integrates androgen and mTOR signaling in prostate cancer.

Jin Y, Qu S, Tesikova M, Wang L, Kristian A, Mælandsmo GM, Kong H, Zhang T, Jerónimo C, Teixeira MR, Yuca E, Tekedereli I, Gorgulu K, Alpay N, Sood AK, Lopez-Berestein G, Danielsen HE, Ozpolat B, Saatcioglu F.

Proc Natl Acad Sci U S A. 2013 Jul 9;110(28):E2572-81. doi: 10.1073/pnas.1304318110. Epub 2013 Jun 24.

17.

Signal integration by mTORC1 coordinates nutrient input with biosynthetic output.

Dibble CC, Manning BD.

Nat Cell Biol. 2013 Jun;15(6):555-64. doi: 10.1038/ncb2763. Review.

18.

mTOR signaling for biological control and cancer.

Alayev A, Holz MK.

J Cell Physiol. 2013 Aug;228(8):1658-64. doi: 10.1002/jcp.24351. Review.

19.

Regulated in development and DNA damage responses -1 (REDD1) protein contributes to insulin signaling pathway in adipocytes.

Regazzetti C, Dumas K, Le Marchand-Brustel Y, Peraldi P, Tanti JF, Giorgetti-Peraldi S.

PLoS One. 2012;7(12):e52154. doi: 10.1371/journal.pone.0052154. Epub 2012 Dec 18.

20.

Chemical inhibition of RNA viruses reveals REDD1 as a host defense factor.

Mata MA, Satterly N, Versteeg GA, Frantz D, Wei S, Williams N, Schmolke M, Peña-Llopis S, Brugarolas J, Forst CV, White MA, García-Sastre A, Roth MG, Fontoura BM.

Nat Chem Biol. 2011 Sep 11;7(10):712-9. doi: 10.1038/nchembio.645.

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