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Items: 13


Capturing Biological Activity in Natural Product Fragments by Chemical Synthesis.

Crane EA, Gademann K.

Angew Chem Int Ed Engl. 2016 Mar 14;55(12):3882-902. doi: 10.1002/anie.201505863. Epub 2016 Feb 2. Review.


Intercellular communication in malignant pleural mesothelioma: properties of tunneling nanotubes.

Ady JW, Desir S, Thayanithy V, Vogel RI, Moreira AL, Downey RJ, Fong Y, Manova-Todorova K, Moore MA, Lou E.

Front Physiol. 2014 Oct 31;5:400. doi: 10.3389/fphys.2014.00400. eCollection 2014.


Migrastatin analogues inhibit canine mammary cancer cell migration and invasion.

Majchrzak K, Lo Re D, Gajewska M, Bulkowska M, Homa A, Pawłowski K, Motyl T, Murphy PV, Król M.

PLoS One. 2013 Oct 8;8(10):e76789. doi: 10.1371/journal.pone.0076789. eCollection 2013.


Post-polyketide synthase steps in iso-migrastatin biosynthesis, featuring tailoring enzymes with broad substrate specificity.

Ma M, Kwong T, Lim SK, Ju J, Lohman JR, Shen B.

J Am Chem Soc. 2013 Feb 20;135(7):2489-92. doi: 10.1021/ja4002635. Epub 2013 Feb 11.


Fusarisetin A: Scalable Total Synthesis and Related Studies.

Xu J, Caro-Diaz EJ, Lacoske MH, Hung CI, Jamora C, Theodorakis EA.

Chem Sci. 2012 Jan 1;3(12):3378-3386. Epub 2012 Aug 23.


Synthetic studies toward (+)-cortistatin A.

Wang Z, Dai M, Park PK, Danishefsky SJ.

Tetrahedron. 2011 Dec 30;67(52):10249-10260. Epub 2011 Oct 29.


Is there no end to the total syntheses of strychnine? Lessons learned in strategy and tactics in total synthesis.

Cannon JS, Overman LE.

Angew Chem Int Ed Engl. 2012 Apr 27;51(18):4288-311. doi: 10.1002/anie.201107385. Epub 2012 Mar 19. Review.


Tumor metastasis: molecular insights and evolving paradigms.

Valastyan S, Weinberg RA.

Cell. 2011 Oct 14;147(2):275-92. doi: 10.1016/j.cell.2011.09.024. Review.


Emergence of potent inhibitors of metastasis in lung cancer via syntheses based on migrastatin.

Lecomte N, Njardarson JT, Nagorny P, Yang G, Downey R, Ouerfelli O, Moore MA, Danishefsky SJ.

Proc Natl Acad Sci U S A. 2011 Sep 13;108(37):15074-8. doi: 10.1073/pnas.1015247108. Epub 2011 Aug 1.


Activation of miR-31 function in already-established metastases elicits metastatic regression.

Valastyan S, Chang A, Benaich N, Reinhardt F, Weinberg RA.

Genes Dev. 2011 Mar 15;25(6):646-59. doi: 10.1101/gad.2004211. Retraction in: Genes Dev. 2015 Mar 15;29(6):686.


Multifaceted modes of action for the glutarimide-containing polyketides revealed.

Rajski SR, Shen B.

Chembiochem. 2010 Sep 24;11(14):1951-4. doi: 10.1002/cbic.201000370. No abstract available.


Synthesis and evaluation of antimigratory and antiproliferative activities of lipid-linked [13]-macro-dilactones.

Magpusao AN, Desmond RT, Billings KJ, Fenteany G, Peczuh MW.

Bioorg Med Chem Lett. 2010 Sep 15;20(18):5472-6. doi: 10.1016/j.bmcl.2010.07.083. Epub 2010 Jul 25.


Confirmation of the Structures of Synthetic Derivatives of Migrastatin in the Light of Recently Disclosed Crystallographically Based Claims.

Nagorny P, Krauss I, Njardarson JT, Perez L, Gaul C, Yang G, Ouerfelli O, Danishefsky SJ.

Tetrahedron Lett. 2010 Jul 28;51(30):3873-3875.

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