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Structure-Based Understanding of Binding Affinity and Mode of Estrogen Receptor α Agonists and Antagonists.

Lee S, Barron MG.

PLoS One. 2017 Jan 6;12(1):e0169607. doi: 10.1371/journal.pone.0169607.


CHARMM Force Field Parameterization of Peroxisome Proliferator-Activated Receptor γ Ligands.

Mottin M, Souza PC, Ricci CG, Skaf MS.

Int J Mol Sci. 2016 Dec 22;18(1). pii: E15. doi: 10.3390/ijms18010015.


NPAS1-ARNT and NPAS3-ARNT crystal structures implicate the bHLH-PAS family as multi-ligand binding transcription factors.

Wu D, Su X, Potluri N, Kim Y, Rastinejad F.

Elife. 2016 Oct 26;5. pii: e18790. doi: 10.7554/eLife.18790.


Tazarotene-induced gene 2 is associated with poor survival in non-small cell lung cancer.

Cai Q, Huang Z, Qi L, Wang T, Shen Y, Huang J.

Oncol Lett. 2016 Oct;12(4):2680-2685.


Reconfiguring the AR-TIF2 Protein-Protein Interaction HCS Assay in Prostate Cancer Cells and Characterizing the Hits from a LOPAC Screen.

Fancher AT, Hua Y, Camarco DP, Close DA, Strock CJ, Johnston PA.

Assay Drug Dev Technol. 2016 Oct;14(8):453-477.


Steroid hormone receptors and prostate cancer: role of structural dynamics in therapeutic targeting.

Kumar R.

Asian J Androl. 2016 Sep-Oct;18(5):682-6. doi: 10.4103/1008-682X.183380. Review.


Interplay between steroid hormone activation of the unfolded protein response and nuclear receptor action.

Zheng X, Andruska N, Yu L, Mao C, Kim JE, Livezey M, Helferich WG, Shapiro DJ.

Steroids. 2016 Oct;114:2-6. doi: 10.1016/j.steroids.2016.03.014. Review.


What's new in estrogen receptor action in the female reproductive tract.

Hewitt SC, Winuthayanon W, Korach KS.

J Mol Endocrinol. 2016 Feb;56(2):R55-71. doi: 10.1530/JME-15-0254. Review.


Allosteric Pathways in the PPARγ-RXRα nuclear receptor complex.

Ricci CG, Silveira RL, Rivalta I, Batista VS, Skaf MS.

Sci Rep. 2016 Jan 29;6:19940. doi: 10.1038/srep19940.


Endocrine resistance in breast cancer--An overview and update.

Clarke R, Tyson JJ, Dixon JM.

Mol Cell Endocrinol. 2015 Dec 15;418 Pt 3:220-34. doi: 10.1016/j.mce.2015.09.035. Review.


Direct and Propagated Effects of Small Molecules on Protein-Protein Interaction Networks.

Cesa LC, Mapp AK, Gestwicki JE.

Front Bioeng Biotechnol. 2015 Aug 24;3:119. doi: 10.3389/fbioe.2015.00119. Review.


Structural mechanism for signal transduction in RXR nuclear receptor heterodimers.

Kojetin DJ, Matta-Camacho E, Hughes TS, Srinivasan S, Nwachukwu JC, Cavett V, Nowak J, Chalmers MJ, Marciano DP, Kamenecka TM, Shulman AI, Rance M, Griffin PR, Bruning JB, Nettles KW.

Nat Commun. 2015 Aug 20;6:8013. doi: 10.1038/ncomms9013.


In Silico Adoption of an Orphan Nuclear Receptor NR4A1.

Lanig H, Reisen F, Whitley D, Schneider G, Banting L, Clark T.

PLoS One. 2015 Aug 13;10(8):e0135246. doi: 10.1371/journal.pone.0135246.


Nuclear hormone receptors put immunity on sterols.

Santori FR.

Eur J Immunol. 2015 Oct;45(10):2730-41. doi: 10.1002/eji.201545712. Review.


International Union of Basic and Clinical Pharmacology. XCVII. G Protein-Coupled Estrogen Receptor and Its Pharmacologic Modulators.

Prossnitz ER, Arterburn JB.

Pharmacol Rev. 2015 Jul;67(3):505-40. doi: 10.1124/pr.114.009712. Review.


Molecular mechanisms of transcriptional control by Rev-erbα: An energetic foundation for reconciling structure and binding with biological function.

Vaissière A, Berger S, Harrus D, Dacquet C, Le Maire A, Boutin JA, Ferry G, Royer CA.

Protein Sci. 2015 Jul;24(7):1129-46. doi: 10.1002/pro.2701.


Minor Structural Change to Tertiary Sulfonamide RORc Ligands Led to Opposite Mechanisms of Action.

René O, Fauber BP, Boenig Gde L, Burton B, Eidenschenk C, Everett C, Gobbi A, Hymowitz SG, Johnson AR, Kiefer JR, Liimatta M, Lockey P, Norman M, Ouyang W, Wallweber HA, Wong H.

ACS Med Chem Lett. 2014 Dec 4;6(3):276-81. doi: 10.1021/ml500420y.


Membrane-initiated non-genomic signaling by estrogens in the hypothalamus: cross-talk with glucocorticoids with implications for behavior.

Rainville J, Pollard K, Vasudevan N.

Front Endocrinol (Lausanne). 2015 Feb 16;6:18. doi: 10.3389/fendo.2015.00018. Review.

Free PMC Article

Targeting cholesterol homeostasis to fight hearing loss: a new perspective.

Malgrange B, Varela-Nieto I, de Medina P, Paillasse MR.

Front Aging Neurosci. 2015 Jan 29;7:3. doi: 10.3389/fnagi.2015.00003. Review.


Identification of natural RORγ ligands that regulate the development of lymphoid cells.

Santori FR, Huang P, van de Pavert SA, Douglass EF Jr, Leaver DJ, Haubrich BA, Keber R, Lorbek G, Konijn T, Rosales BN, Rozman D, Horvat S, Rahier A, Mebius RE, Rastinejad F, Nes WD, Littman DR.

Cell Metab. 2015 Feb 3;21(2):286-97. doi: 10.1016/j.cmet.2015.01.004.

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