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A Case of Neonatal Marfan Syndrome: A Management Conundrum and the Role of a Multidisciplinary Team.

Carande EJ, Bilton SJ, Adwani S.

Case Rep Pediatr. 2017;2017:8952428. doi: 10.1155/2017/8952428.


Angiopoietin-2 attenuates angiotensin II-induced aortic aneurysm and atherosclerosis in apolipoprotein E-deficient mice.

Yu H, Moran CS, Trollope AF, Woodward L, Kinobe R, Rush CM, Golledge J.

Sci Rep. 2016 Oct 21;6:35190. doi: 10.1038/srep35190.


Smooth muscle cell-specific Tgfbr1 deficiency promotes aortic aneurysm formation by stimulating multiple signaling events.

Yang P, Schmit BM, Fu C, DeSart K, Oh SP, Berceli SA, Jiang Z.

Sci Rep. 2016 Oct 14;6:35444. doi: 10.1038/srep35444.


Calorie restriction protects against experimental abdominal aortic aneurysms in mice.

Liu Y, Wang TT, Zhang R, Fu WY, Wang X, Wang F, Gao P, Ding YN, Xie Y, Hao DL, Chen HZ, Liu DP.

J Exp Med. 2016 Oct 17;213(11):2473-2488.


Cytokine amplification and macrophage effector functions in aortic inflammation and abdominal aortic aneurysm formation.

Ijaz T, Tilton RG, Brasier AR.

J Thorac Dis. 2016 Aug;8(8):E746-54. doi: 10.21037/jtd.2016.06.37.


Insights into ascending aortic aneurysm pathogenesis using in vivo and ex vivo imaging systems in angiotensin II-infused mice.

Sheppard MB, Daugherty A, Lu H.

J Thorac Dis. 2016 Aug;8(8):E822-4. doi: 10.21037/jtd.2016.07.63. No abstract available.


Local Application of Leptin Antagonist Attenuates Angiotensin II-Induced Ascending Aortic Aneurysm and Cardiac Remodeling.

Ben-Zvi D, Savion N, Kolodgie F, Simon A, Fisch S, Schäfer K, Bachner-Hinenzon N, Cao X, Gertler A, Solomon G, Kachel E, Raanani E, Lavee J, Kotev Emeth S, Virmani R, Schoen FJ, Schneiderman J.

J Am Heart Assoc. 2016 May 3;5(5). pii: e003474. doi: 10.1161/JAHA.116.003474.


TGF-β Neutralization Enhances AngII-Induced Aortic Rupture and Aneurysm in Both Thoracic and Abdominal Regions.

Chen X, Rateri DL, Howatt DA, Balakrishnan A, Moorleghen JJ, Cassis LA, Daugherty A.

PLoS One. 2016 Apr 22;11(4):e0153811. doi: 10.1371/journal.pone.0153811.


Leukocyte Calpain Deficiency Reduces Angiotensin II-Induced Inflammation and Atherosclerosis But Not Abdominal Aortic Aneurysms in Mice.

Howatt DA, Balakrishnan A, Moorleghen JJ, Muniappan L, Rateri DL, Uchida HA, Takano J, Saido TC, Chishti AH, Baud L, Subramanian V.

Arterioscler Thromb Vasc Biol. 2016 May;36(5):835-45. doi: 10.1161/ATVBAHA.116.307285.


Cardiovascular manifestations of renovascular hypertension in diabetic mice.

Kashyap S, Engel S, Osman M, Al-Saiegh Y, Wongjarupong A, Grande JP.

PeerJ. 2016 Feb 22;4:e1736. doi: 10.7717/peerj.1736.


Subcutaneous Angiotensin II Infusion using Osmotic Pumps Induces Aortic Aneurysms in Mice.

Lu H, Howatt DA, Balakrishnan A, Moorleghen JJ, Rateri DL, Cassis LA, Daugherty A.

J Vis Exp. 2015 Sep 28;(103). doi: 10.3791/53191.


Thrombospondin-1 (TSP1) contributes to the development of vascular inflammation by regulating monocytic cell motility in mouse models of abdominal aortic aneurysm.

Liu Z, Morgan S, Ren J, Wang Q, Annis DS, Mosher DF, Zhang J, Sorenson CM, Sheibani N, Liu B.

Circ Res. 2015 Jul 3;117(2):129-41. doi: 10.1161/CIRCRESAHA.117.305262. Erratum in: Circ Res. 2015 Aug 14;117(5):e55.


Identification and characterization of CD4(+)AT2(+) T lymphocyte population in human thoracic aortic aneurysm.

Wang C, Wu T, Hu X, Huang R, Lian F, Wang W, Feng Y, Xie B, Hu Z, Zhai X, Liu J, Gu J, Chen Y, Li J, Xue S.

Am J Transl Res. 2015 Feb 15;7(2):232-41.


Non coding RNAs in aortic aneurysmal disease.

Duggirala A, Delogu F, Angelini TG, Smith T, Caputo M, Rajakaruna C, Emanueli C.

Front Genet. 2015 Apr 1;6:125. doi: 10.3389/fgene.2015.00125. Review.


Functional interaction between angiotensin II receptor type 1 and chemokine (C-C motif) receptor 2 with implications for chronic kidney disease.

Ayoub MA, Zhang Y, Kelly RS, See HB, Johnstone EK, McCall EA, Williams JH, Kelly DJ, Pfleger KD.

PLoS One. 2015 Mar 25;10(3):e0119803. doi: 10.1371/journal.pone.0119803.


RGS1 regulates myeloid cell accumulation in atherosclerosis and aortic aneurysm rupture through altered chemokine signalling.

Patel J, McNeill E, Douglas G, Hale AB, de Bono J, Lee R, Iqbal AJ, Regan-Komito D, Stylianou E, Greaves DR, Channon KM.

Nat Commun. 2015 Mar 18;6:6614. doi: 10.1038/ncomms7614.


Angiotensin II increases matrix metalloproteinase 2 expression in human aortic smooth muscle cells via AT1R and ERK1/2.

Wang C, Qian X, Sun X, Chang Q.

Exp Biol Med (Maywood). 2015 Dec;240(12):1564-71. doi: 10.1177/1535370215576312.


Deficiency of Endogenous Acute-Phase Serum Amyloid A Protects apoE-/- Mice From Angiotensin II-Induced Abdominal Aortic Aneurysm Formation.

Webb NR, De Beer MC, Wroblewski JM, Ji A, Bailey W, Shridas P, Charnigo RJ, Noffsinger VP, Witta J, Howatt DA, Balakrishnan A, Rateri DL, Daugherty A, De Beer FC.

Arterioscler Thromb Vasc Biol. 2015 May;35(5):1156-65. doi: 10.1161/ATVBAHA.114.304776.


AT1 receptor antagonism to reduce aortic expansion in Marfan syndrome: lost in translation or in need of different interpretation?

Mallat Z, Daugherty A.

Arterioscler Thromb Vasc Biol. 2015 Feb;35(2):e10-2. doi: 10.1161/ATVBAHA.114.305173. No abstract available.

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