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Items: 1 to 20 of 436


The NAD World 2.0: the importance of the inter-tissue communication mediated by NAMPT/NAD+/SIRT1 in mammalian aging and longevity control.

Imai SI.

NPJ Syst Biol Appl. 2016 Aug 18;2:16018. doi: 10.1038/npjsba.2016.18. eCollection 2016. Review.


The Identification of a SIRT6 Activator from Brown Algae Fucus distichus.

Rahnasto-Rilla MK, McLoughlin P, Kulikowicz T, Doyle M, Bohr VA, Lahtela-Kakkonen M, Ferrucci L, Hayes M, Moaddel R.

Mar Drugs. 2017 Jun 21;15(6). pii: E190. doi: 10.3390/md15060190.


Obesity-Linked Phosphorylation of SIRT1 by Casein Kinase 2 Inhibits Its Nuclear Localization and Promotes Fatty Liver.

Choi SE, Kwon S, Seok S, Xiao Z, Lee KW, Kang Y, Li X, Shinoda K, Kajimura S, Kemper B, Kemper JK.

Mol Cell Biol. 2017 Jul 14;37(15). pii: e00006-17. doi: 10.1128/MCB.00006-17. Print 2017 Aug 1.


The mitochondrial SIR2 related protein 2 (SIR2RP2) impacts Leishmania donovani growth and infectivity.

Mittal N, Muthuswami R, Madhubala R.

PLoS Negl Trop Dis. 2017 May 11;11(5):e0005590. doi: 10.1371/journal.pntd.0005590. eCollection 2017 May.


A conserved NAD+ binding pocket that regulates protein-protein interactions during aging.

Li J, Bonkowski MS, Moniot S, Zhang D, Hubbard BP, Ling AJ, Rajman LA, Qin B, Lou Z, Gorbunova V, Aravind L, Steegborn C, Sinclair DA.

Science. 2017 Mar 24;355(6331):1312-1317. doi: 10.1126/science.aad8242.


Adipose tissue NAD+ biology in obesity and insulin resistance: From mechanism to therapy.

Yamaguchi S, Yoshino J.

Bioessays. 2017 May;39(5). doi: 10.1002/bies.201600227. Epub 2017 Mar 15. Review.


Nicotinamide N-Methyltransferase: More Than a Vitamin B3 Clearance Enzyme.

Pissios P.

Trends Endocrinol Metab. 2017 May;28(5):340-353. doi: 10.1016/j.tem.2017.02.004. Epub 2017 Mar 11. Review.


Epigenetic Modulation of Stem Cells in Neurodevelopment: The Role of Methylation and Acetylation.

Podobinska M, Szablowska-Gadomska I, Augustyniak J, Sandvig I, Sandvig A, Buzanska L.

Front Cell Neurosci. 2017 Feb 7;11:23. doi: 10.3389/fncel.2017.00023. eCollection 2017. Review.


Gamma-tocopherol supplementation ameliorated hyper-inflammatory response during the early cutaneous wound healing in alloxan-induced diabetic mice.

Shin J, Yang SJ, Lim Y.

Exp Biol Med (Maywood). 2017 Mar;242(5):505-515. doi: 10.1177/1535370216683836. Epub 2016 Dec 13.


PARPs and ADP-ribosylation: recent advances linking molecular functions to biological outcomes.

Gupte R, Liu Z, Kraus WL.

Genes Dev. 2017 Jan 15;31(2):101-126. doi: 10.1101/gad.291518.116. Review.


Nrf2 regulates mass accrual and the antioxidant endogenous response in bone differently depending on the sex and age.

Pellegrini GG, Cregor M, McAndrews K, Morales CC, McCabe LD, McCabe GP, Peacock M, Burr D, Weaver C, Bellido T.

PLoS One. 2017 Feb 2;12(2):e0171161. doi: 10.1371/journal.pone.0171161. eCollection 2017.


The expression of SIRT1 regulates the metastaticplasticity of chondrosarcoma cells by inducing epithelial-mesenchymal transition.

Feng H, Wang J, Xu J, Xie C, Gao F, Li Z.

Sci Rep. 2017 Jan 23;7:41203. doi: 10.1038/srep41203.


SIRT1 plays a neuroprotective role in traumatic brain injury in rats via inhibiting the p38 MAPK pathway.

Yang H, Gu ZT, Li L, Maegele M, Zhou BY, Li F, Zhao M, Zhao KS.

Acta Pharmacol Sin. 2017 Feb;38(2):168-181. doi: 10.1038/aps.2016.130. Epub 2016 Dec 26.


SIRT7 Is an RNA-Activated Protein Lysine Deacylase.

Tong Z, Wang M, Wang Y, Kim DD, Grenier JK, Cao J, Sadhukhan S, Hao Q, Lin H.

ACS Chem Biol. 2017 Jan 20;12(1):300-310. doi: 10.1021/acschembio.6b00954. Epub 2016 Dec 20.


Sirt1 regulates glial progenitor proliferation and regeneration in white matter after neonatal brain injury.

Jablonska B, Gierdalski M, Chew LJ, Hawley T, Catron M, Lichauco A, Cabrera-Luque J, Yuen T, Rowitch D, Gallo V.

Nat Commun. 2016 Dec 19;7:13866. doi: 10.1038/ncomms13866.


Sirtuins in metabolism, DNA repair and cancer.

Mei Z, Zhang X, Yi J, Huang J, He J, Tao Y.

J Exp Clin Cancer Res. 2016 Dec 5;35(1):182. Review.


SIRT1 protects the heart from ER stress-induced cell death through eIF2α deacetylation.

Prola A, Silva JP, Guilbert A, Lecru L, Piquereau J, Ribeiro M, Mateo P, Gressette M, Fortin D, Boursier C, Gallerne C, Caillard A, Samuel JL, François H, Sinclair DA, Eid P, Ventura-Clapier R, Garnier A, Lemaire C.

Cell Death Differ. 2017 Feb;24(2):343-356. doi: 10.1038/cdd.2016.138. Epub 2016 Dec 2.


Long-term caloric restriction in ApoE-deficient mice results in neuroprotection via Fgf21-induced AMPK/mTOR pathway.

Rühlmann C, Wölk T, Blümel T, Stahn L, Vollmar B, Kuhla A.

Aging (Albany NY). 2016 Nov 29;8(11):2777-2789. doi: 10.18632/aging.101086.


CHFR negatively regulates SIRT1 activity upon oxidative stress.

Kim M, Kwon YE, Song JO, Bae SJ, Seol JH.

Sci Rep. 2016 Nov 24;6:37578. doi: 10.1038/srep37578.

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