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Items: 1 to 20 of 174


Association between BRCA1 P871L polymorphism and cancer risk: evidence from a meta-analysis.

Miao L, Yu Y, Ji Y, Zhang B, Yuan Z, Du Y, Zhu L, Wang R, Chen N, Yuan H.

Oncotarget. 2017 May 2;8(18):30587-30594. doi: 10.18632/oncotarget.15739. Review.


Activity of trabectedin and the PARP inhibitor rucaparib in soft-tissue sarcomas.

Laroche A, Chaire V, Le Loarer F, Algéo MP, Rey C, Tran K, Lucchesi C, Italiano A.

J Hematol Oncol. 2017 Apr 11;10(1):84. doi: 10.1186/s13045-017-0451-x.


Functional and mutational landscapes of BRCA1 for homology-directed repair and therapy resistance.

Anantha RW, Simhadri S, Foo TK, Miao S, Liu J, Shen Z, Ganesan S, Xia B.

Elife. 2017 Apr 11;6. pii: e21350. doi: 10.7554/eLife.21350.


What can yeast tell us about breast cancer?

Golubeva V, Monteiro AN.

Cell Cycle. 2017 Jan 17;16(2):157-158. doi: 10.1080/15384101.2016.1230376. Epub 2016 Dec 22. No abstract available.


Repair of DNA Double-Strand Breaks in Heterochromatin.

Watts FZ.

Biomolecules. 2016 Dec 16;6(4). pii: E47. doi: 10.3390/biom6040047. Review.


Sam68 Is Required for DNA Damage Responses via Regulating Poly(ADP-ribosyl)ation.

Sun X, Fu K, Hodgson A, Wier EM, Wen MG, Kamenyeva O, Xia X, Koo LY, Wan F.

PLoS Biol. 2016 Sep 16;14(9):e1002543. doi: 10.1371/journal.pbio.1002543. eCollection 2016 Sep.


RNF168 and USP10 regulate topoisomerase IIα function via opposing effects on its ubiquitylation.

Guturi KK, Bohgaki M, Bohgaki T, Srikumar T, Ng D, Kumareswaran R, El Ghamrasni S, Jeon J, Patel P, Eldin MS, Bristow R, Cheung P, Stewart GS, Raught B, Hakem A, Hakem R.

Nat Commun. 2016 Aug 25;7:12638. doi: 10.1038/ncomms12638.


A genome-wide screening uncovers the role of CCAR2 as an antagonist of DNA end resection.

López-Saavedra A, Gómez-Cabello D, Domínguez-Sánchez MS, Mejías-Navarro F, Fernández-Ávila MJ, Dinant C, Martínez-Macías MI, Bartek J, Huertas P.

Nat Commun. 2016 Aug 9;7:12364. doi: 10.1038/ncomms12364.


Expression of cancer related BRCA1 missense variants decreases MMS-induced recombination in Saccharomyces cerevisiae without altering its nuclear localization.

Lodovichi S, Vitello M, Cervelli T, Galli A.

Cell Cycle. 2016 Oct 17;15(20):2723-31. doi: 10.1080/15384101.2016.1215389. Epub 2016 Aug 2.


Cell cycle-dependent inhibition of 53BP1 signaling by BRCA1.

Feng L, Li N, Li Y, Wang J, Gao M, Wang W, Chen J.

Cell Discov. 2015 Aug 4;1:15019. doi: 10.1038/celldisc.2015.19. eCollection 2015.


RING domain-deficient BRCA1 promotes PARP inhibitor and platinum resistance.

Wang Y, Krais JJ, Bernhardy AJ, Nicolas E, Cai KQ, Harrell MI, Kim HH, George E, Swisher EM, Simpkins F, Johnson N.

J Clin Invest. 2016 Aug 1;126(8):3145-57. doi: 10.1172/JCI87033. Epub 2016 Jul 25.


BRCA1185delAG tumors may acquire therapy resistance through expression of RING-less BRCA1.

Drost R, Dhillon KK, van der Gulden H, van der Heijden I, Brandsma I, Cruz C, Chondronasiou D, Castroviejo-Bermejo M, Boon U, Schut E, van der Burg E, Wientjens E, Pieterse M, Klijn C, Klarenbeek S, Loayza-Puch F, Elkon R, van Deemter L, Rottenberg S, van de Ven M, Dekkers DH, Demmers JA, van Gent DC, Agami R, Balmaña J, Serra V, Taniguchi T, Bouwman P, Jonkers J.

J Clin Invest. 2016 Aug 1;126(8):2903-18. doi: 10.1172/JCI70196. Epub 2016 Jul 25.


Writers, Readers, and Erasers of Histone Ubiquitylation in DNA Double-Strand Break Repair.

Smeenk G, Mailand N.

Front Genet. 2016 Jun 28;7:122. doi: 10.3389/fgene.2016.00122. eCollection 2016. Review.


TRIP12 as a mediator of human papillomavirus/p16-related radiation enhancement effects.

Wang L, Zhang P, Molkentine DP, Chen C, Molkentine JM, Piao H, Raju U, Zhang J, Valdecanas DR, Tailor RC, Thames HD, Buchholz TA, Chen J, Ma L, Mason KA, Ang KK, Meyn RE, Skinner HD.

Oncogene. 2017 Feb 9;36(6):820-828. doi: 10.1038/onc.2016.250. Epub 2016 Jul 18.


BRCA1/FANCD2/BRG1-Driven DNA Repair Stabilizes the Differentiation State of Human Mammary Epithelial Cells.

Wang H, Bierie B, Li AG, Pathania S, Toomire K, Dimitrov SD, Liu B, Gelman R, Giobbie-Hurder A, Feunteun J, Polyak K, Livingston DM.

Mol Cell. 2016 Jul 21;63(2):277-92. doi: 10.1016/j.molcel.2016.05.038. Epub 2016 Jun 30.


Regulation of cancer stem cells by RING finger ubiquitin ligases.

Kang B, Sun XH.

Stem Cell Investig. 2014 Feb 9;1:5. doi: 10.3978/j.issn.2306-9759.2014.01.01. eCollection 2014. Review.


The Lys63-deubiquitylating Enzyme BRCC36 Limits DNA Break Processing and Repair.

Ng HM, Wei L, Lan L, Huen MS.

J Biol Chem. 2016 Jul 29;291(31):16197-207. doi: 10.1074/jbc.M116.731927. Epub 2016 Jun 10.


Androgen receptor expression predicts different clinical outcomes for breast cancer patients stratified by hormone receptor status.

Jiang HS, Kuang XY, Sun WL, Xu Y, Zheng YZ, Liu YR, Lang GT, Qiao F, Hu X, Shao ZM.

Oncotarget. 2016 Jul 5;7(27):41285-41293. doi: 10.18632/oncotarget.9778.


Germline BRCA1 mutation reprograms breast epithelial cell metabolism towards mitochondrial-dependent biosynthesis: evidence for metformin-based "starvation" strategies in BRCA1 carriers.

Cuyàs E, Fernández-Arroyo S, Alarcón T, Lupu R, Joven J, Menendez JA.

Oncotarget. 2016 Aug 16;7(33):52974-52992. doi: 10.18632/oncotarget.9732.


Unsolved mystery: the role of BRCA1 in DNA end-joining.

Saha J, Davis AJ.

J Radiat Res. 2016 Aug;57 Suppl 1:i18-i24. doi: 10.1093/jrr/rrw032. Epub 2016 May 10. Review.

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