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Items: 1 to 20 of 22


Silybin attenuates LPS-induced lung injury in mice by inhibiting NF-κB signaling and NLRP3 activation.

Zhang B, Wang B, Cao S, Wang Y, Wu D.

Int J Mol Med. 2017 May;39(5):1111-1118. doi: 10.3892/ijmm.2017.2935. Epub 2017 Mar 27.


Inhibition of ERK1/2 by silymarin in mouse mesangial cells.

Youn CK, Cho SI, Lee MY, Jeon YJ, Lee SK.

Korean J Physiol Pharmacol. 2017 Jan;21(1):117-124. doi: 10.4196/kjpp.2017.21.1.117. Epub 2016 Dec 21.


Silibinin Inhibits Platelet-Derived Growth Factor-Driven Cell Proliferation via Downregulation of N-Glycosylation in Human Tenon's Fibroblasts in a Proteasome-Dependent Manner.

Chen YH, Chen CL, Lu DW, Liang CM, Tai MC, Chen JT.

PLoS One. 2016 Dec 28;11(12):e0168765. doi: 10.1371/journal.pone.0168765. eCollection 2016.


In vitro drug release characteristic and cytotoxic activity of silibinin-loaded single walled carbon nanotubes functionalized with biocompatible polymers.

Tan JM, Karthivashan G, Gani SA, Fakurazi S, Hussein MZ.

Chem Cent J. 2016 Dec 12;10:81. doi: 10.1186/s13065-016-0228-2. eCollection 2016.


New Aspects of Silibinin Stereoisomers and their 3-O-galloyl Derivatives on Cytotoxicity and Ceramide Metabolism in Hep G2 hepatocarcinoma Cell Line.

Mashhadi Akbar Boojar M, Hassanipour M, Ejtemaei Mehr S, Mashhadi Akbar Boojar M, Dehpour AR.

Iran J Pharm Res. 2016 Summer;15(3):421-433.


Botanicals and Their Bioactive Phytochemicals for Women's Health.

Dietz BM, Hajirahimkhan A, Dunlap TL, Bolton JL.

Pharmacol Rev. 2016 Oct;68(4):1026-1073. Review.


Corneal toxicity induced by vesicating agents and effective treatment options.

Goswami DG, Tewari-Singh N, Agarwal R.

Ann N Y Acad Sci. 2016 Jun;1374(1):193-201. doi: 10.1111/nyas.13121. Epub 2016 Jun 21.


Optimization and single-laboratory validation of a method for the determination of flavonolignans in milk thistle seeds by high-performance liquid chromatography with ultraviolet detection.

Mudge E, Paley L, Schieber A, Brown PN.

Anal Bioanal Chem. 2015 Oct;407(25):7657-66. doi: 10.1007/s00216-015-8925-6. Epub 2015 Jul 31.


Silibinin down-regulates FAT10 and modulate TNF-α/IFN-γ-induced chromosomal instability and apoptosis sensitivity.

Gao Y, Theng SS, Mah WC, Lee CG.

Biol Open. 2015 Jul 3;4(8):961-9. doi: 10.1242/bio.011189.


Silibinin and its 2,3-dehydro-derivative inhibit basal cell carcinoma growth via suppression of mitogenic signaling and transcription factors activation.

Tilley C, Deep G, Agarwal C, Wempe MF, Biedermann D, Valentová K, Kren V, Agarwal R.

Mol Carcinog. 2016 Jan;55(1):3-14. doi: 10.1002/mc.22253. Epub 2014 Dec 9.


Molecular insights into the anti-cancer properties of traditional Tibetan medicine Yukyung Karne.

Choedon T, Dolma D, Mathan G, Kumar V.

BMC Complement Altern Med. 2014 Oct 7;14:380. doi: 10.1186/1472-6882-14-380.


Synthesis, structure-activity relationship studies, and antibacterial evaluation of 4-chromanones and chalcones, as well as olympicin A and derivatives.

Feng L, Maddox MM, Alam MZ, Tsutsumi LS, Narula G, Bruhn DF, Wu X, Sandhaus S, Lee RB, Simmons CJ, Tse-Dinh YC, Hurdle JG, Lee RE, Sun D.

J Med Chem. 2014 Oct 23;57(20):8398-420. doi: 10.1021/jm500853v. Epub 2014 Oct 7.


Regulation of Nrf2-an update.

Niture SK, Khatri R, Jaiswal AK.

Free Radic Biol Med. 2014 Jan;66:36-44. doi: 10.1016/j.freeradbiomed.2013.02.008. Epub 2013 Feb 19. Review.


Silibinin inhibits VEGF secretion and age-related macular degeneration in a hypoxia-dependent manner through the PI-3 kinase/Akt/mTOR pathway.

Lin CH, Li CH, Liao PL, Tse LS, Huang WK, Cheng HW, Cheng YW.

Br J Pharmacol. 2013 Feb;168(4):920-31. doi: 10.1111/j.1476-5381.2012.02227.x.


Silibinin, dexamethasone, and doxycycline as potential therapeutic agents for treating vesicant-inflicted ocular injuries.

Tewari-Singh N, Jain AK, Inturi S, Ammar DA, Agarwal C, Tyagi P, Kompella UB, Enzenauer RW, Petrash JM, Agarwal R.

Toxicol Appl Pharmacol. 2012 Oct 1;264(1):23-31. doi: 10.1016/j.taap.2012.07.014. Epub 2012 Jul 24.


Silibinin inhibits Wnt/β-catenin signaling by suppressing Wnt co-receptor LRP6 expression in human prostate and breast cancer cells.

Lu W, Lin C, King TD, Chen H, Reynolds RC, Li Y.

Cell Signal. 2012 Dec;24(12):2291-6. doi: 10.1016/j.cellsig.2012.07.009. Epub 2012 Jul 20.


Therapeutic targets in cancer cell metabolism and autophagy.

Cheong H, Lu C, Lindsten T, Thompson CB.

Nat Biotechnol. 2012 Jul 10;30(7):671-8. doi: 10.1038/nbt.2285. Review.


Synergistic antibacterial effect between silibinin and antibiotics in oral bacteria.

Lee YS, Jang KA, Cha JD.

J Biomed Biotechnol. 2012;2012:618081. doi: 10.1155/2012/618081. Epub 2011 Sep 15.

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