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Items: 1 to 20 of 40

1.

Pre-T Cell Receptors (Pre-TCRs) Leverage Vβ Complementarity Determining Regions (CDRs) and Hydrophobic Patch in Mechanosensing Thymic Self-ligands.

Das DK, Mallis RJ, Duke-Cohan JS, Hussey RE, Tetteh PW, Hilton M, Wagner G, Lang MJ, Reinherz EL.

J Biol Chem. 2016 Dec 2;291(49):25292-25305.

PMID:
27707880
2.

T-cell selection in the thymus: a spatial and temporal perspective.

Kurd N, Robey EA.

Immunol Rev. 2016 May;271(1):114-26. doi: 10.1111/imr.12398. Review.

PMID:
27088910
3.

Non-canonical antagonism of PI3K by the kinase Itpkb delays thymocyte β-selection and renders it Notch-dependent.

Westernberg L, Conche C, Huang YH, Rigaud S, Deng Y, Siegemund S, Mukherjee S, Nosaka L, Das J, Sauer K.

Elife. 2016 Feb 11;5. pii: e10786. doi: 10.7554/eLife.10786.

4.

A dynamic niche provides Kit ligand in a stage-specific manner to the earliest thymocyte progenitors.

Buono M, Facchini R, Matsuoka S, Thongjuea S, Waithe D, Luis TC, Giustacchini A, Besmer P, Mead AJ, Jacobsen SE, Nerlov C.

Nat Cell Biol. 2016 Feb;18(2):157-67. doi: 10.1038/ncb3299.

5.

Asymmetric cell division during T cell development controls downstream fate.

Pham K, Shimoni R, Charnley M, Ludford-Menting MJ, Hawkins ED, Ramsbottom K, Oliaro J, Izon D, Ting SB, Reynolds J, Lythe G, Molina-Paris C, Melichar H, Robey E, Humbert PO, Gu M, Russell SM.

J Cell Biol. 2015 Sep 14;210(6):933-50. doi: 10.1083/jcb.201502053.

6.

Impairment of T cell development and acute inflammatory response in HIV-1 Tat transgenic mice.

Fiume G, Scialdone A, Albano F, Rossi A, Tuccillo FM, Rea D, Palmieri C, Caiazzo E, Cicala C, Bellevicine C, Falcone C, Vecchio E, Pisano A, Ceglia S, Mimmi S, Iaccino E, de Laurentiis A, Pontoriero M, Agosti V, Troncone G, Mignogna C, Palma G, Arra C, Mallardo M, Buonaguro FM, Scala G, Quinto I.

Sci Rep. 2015 Sep 7;5:13864. doi: 10.1038/srep13864.

7.

The Contribution of Chemokines and Migration to the Induction of Central Tolerance in the Thymus.

Hu Z, Lancaster JN, Ehrlich LI.

Front Immunol. 2015 Aug 7;6:398. doi: 10.3389/fimmu.2015.00398. Review.

8.

CXCL12-Producing Vascular Endothelial Niches Control Acute T Cell Leukemia Maintenance.

Pitt LA, Tikhonova AN, Hu H, Trimarchi T, King B, Gong Y, Sanchez-Martin M, Tsirigos A, Littman DR, Ferrando AA, Morrison SJ, Fooksman DR, Aifantis I, Schwab SR.

Cancer Cell. 2015 Jun 8;27(6):755-68. doi: 10.1016/j.ccell.2015.05.002.

9.

Human Peripheral CD4(+) Vδ1(+) γδT Cells Can Develop into αβT Cells.

Ziegler H, Welker C, Sterk M, Haarer J, Rammensee HG, Handgretinger R, Schilbach K.

Front Immunol. 2014 Dec 17;5:645. doi: 10.3389/fimmu.2014.00645.

10.

ShcA regulates thymocyte proliferation through specific transcription factors and a c-Abl-dependent signaling axis.

Trampont PC, Zhang L, Giles AJ, Walk SF, Gu JJ, Pendergast AM, Ravichandran KS.

Mol Cell Biol. 2015 Apr;35(8):1462-76. doi: 10.1128/MCB.01084-14.

11.

ShcA regulates late stages of T cell development and peripheral CD4+ T cell numbers.

Buckley MW, Trampont PC, Arandjelovic S, Fond AM, Juncadella IJ, Ravichandran KS.

J Immunol. 2015 Feb 15;194(4):1665-76. doi: 10.4049/jimmunol.1401728.

12.

CBAP promotes thymocyte negative selection by facilitating T-cell receptor proximal signaling.

Ho KC, Chiang YJ, Lai AC, Liao NS, Chang YJ, Yang-Yen HF, Yen JJ.

Cell Death Dis. 2014 Nov 13;5:e1518. doi: 10.1038/cddis.2014.474.

13.

Unexpected phenotype of mice lacking Shcbp1, a protein induced during T cell proliferation.

Buckley MW, Arandjelovic S, Trampont PC, Kim TS, Braciale TJ, Ravichandran KS.

PLoS One. 2014 Aug 25;9(8):e105576. doi: 10.1371/journal.pone.0105576.

14.

Cutting edge: CXCR4 is critical for CD8+ memory T cell homeostatic self-renewal but not rechallenge self-renewal.

Chaix J, Nish SA, Lin WH, Rothman NJ, Ding L, Wherry EJ, Reiner SL.

J Immunol. 2014 Aug 1;193(3):1013-6. doi: 10.4049/jimmunol.1400488.

15.

Regeneration of the aged thymus by a single transcription factor.

Bredenkamp N, Nowell CS, Blackburn CC.

Development. 2014 Apr;141(8):1627-37. doi: 10.1242/dev.103614.

16.

Multiple levels of chemokine receptor regulation in the control of mouse natural killer cell development.

Bernardini G, Benigni G, Antonangeli F, Ponzetta A, Santoni A.

Front Immunol. 2014 Feb 13;5:44. doi: 10.3389/fimmu.2014.00044. Review.

17.

HIV-1 Nef down-modulates C-C and C-X-C chemokine receptors via ubiquitin and ubiquitin-independent mechanism.

Chandrasekaran P, Moore V, Buckley M, Spurrier J, Kehrl JH, Venkatesan S.

PLoS One. 2014 Jan 29;9(1):e86998. doi: 10.1371/journal.pone.0086998.

18.
19.

Primate lentiviral Nef proteins deregulate T-cell development by multiple mechanisms.

Van Nuffel A, Ariën KK, Stove V, Schindler M, O'Neill E, Schmökel J, Van de Walle I, Naessens E, Vanderstraeten H, Van Landeghem K, Taghon T, Pulkkinen K, Saksela K, Garcia JV, Fackler OT, Kirchhoff F, Verhasselt B.

Retrovirology. 2013 Nov 15;10:137. doi: 10.1186/1742-4690-10-137.

20.

Opposing chemokine gradients control human thymocyte migration in situ.

Halkias J, Melichar HJ, Taylor KT, Ross JO, Yen B, Cooper SB, Winoto A, Robey EA.

J Clin Invest. 2013 May;123(5):2131-42. doi: 10.1172/JCI67175.

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