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Caspase-6 Undergoes a Distinct Helix-Strand Interconversion upon Substrate Binding.

Dagbay KB, Bolik-Coulon N, Savinov SN, Hardy JA.

J Biol Chem. 2017 Mar 24;292(12):4885-4897. doi: 10.1074/jbc.M116.773499. Epub 2017 Feb 2.


Pyruvate Dehydrogenase Kinase-mediated Glycolytic Metabolic Shift in the Dorsal Root Ganglion Drives Painful Diabetic Neuropathy.

Rahman MH, Jha MK, Kim JH, Nam Y, Lee MG, Go Y, Harris RA, Park DH, Kook H, Lee IK, Suk K.

J Biol Chem. 2016 Mar 11;291(11):6011-25. doi: 10.1074/jbc.M115.699215. Epub 2016 Jan 14.


Acid-sensing ion channel 1a contributes to the effect of extracellular acidosis on NLRP1 inflammasome activation in cortical neurons.

Wang YC, Li WZ, Wu Y, Yin YY, Dong LY, Chen ZW, Wu WN.

J Neuroinflammation. 2015 Dec 30;12:246. doi: 10.1186/s12974-015-0465-7.


Ionic homeostasis in brain conditioning.

Cuomo O, Vinciguerra A, Cerullo P, Anzilotti S, Brancaccio P, Bilo L, Scorziello A, Molinaro P, Di Renzo G, Pignataro G.

Front Neurosci. 2015 Aug 10;9:277. doi: 10.3389/fnins.2015.00277. eCollection 2015. Review.


Acid-sensing ion channel 1a drives AMPA receptor plasticity following ischaemia and acidosis in hippocampal CA1 neurons.

Quintana P, Soto D, Poirot O, Zonouzi M, Kellenberger S, Muller D, Chrast R, Cull-Candy SG.

J Physiol. 2015 Oct 1;593(19):4373-86. doi: 10.1113/JP270701. Epub 2015 Aug 18.


Glibenclamide for the treatment of ischemic and hemorrhagic stroke.

Caffes N, Kurland DB, Gerzanich V, Simard JM.

Int J Mol Sci. 2015 Mar 4;16(3):4973-84. doi: 10.3390/ijms16034973. Review.


Context-dependent GluN2B-selective inhibitors of NMDA receptor function are neuroprotective with minimal side effects.

Yuan H, Myers SJ, Wells G, Nicholson KL, Swanger SA, Lyuboslavsky P, Tahirovic YA, Menaldino DS, Ganesh T, Wilson LJ, Liotta DC, Snyder JP, Traynelis SF.

Neuron. 2015 Mar 18;85(6):1305-18. doi: 10.1016/j.neuron.2015.02.008. Epub 2015 Feb 26.


ASICs as therapeutic targets for migraine.

Dussor G.

Neuropharmacology. 2015 Jul;94:64-71. doi: 10.1016/j.neuropharm.2014.12.015. Epub 2015 Jan 9. Review.


Does closure of acid-sensing ion channels reduce ischemia/reperfusion injury in the rat brain?

Wang J, Xu Y, Lian Z, Zhang J, Zhu T, Li M, Wei Y, Dong B.

Neural Regen Res. 2013 May 5;8(13):1169-79. doi: 10.3969/j.issn.1673-5374.2013.13.002.


Dynamic changes in proprotein convertase 2 activity in cortical neurons after ischemia/reperfusion and oxygen-glucose deprivation.

Zhan S, Zhou A, Piper C, Yang T.

Neural Regen Res. 2013 Jan 5;8(1):83-9. doi: 10.3969/j.issn.1673-5374.2013.01.011.


Proton-sensitive cation channels and ion exchangers in ischemic brain injury: new therapeutic targets for stroke?

Leng T, Shi Y, Xiong ZG, Sun D.

Prog Neurobiol. 2014 Apr;115:189-209. doi: 10.1016/j.pneurobio.2013.12.008. Epub 2014 Jan 24. Review.


Ionic regulation of cell volume changes and cell death after ischemic stroke.

Song M, Yu SP.

Transl Stroke Res. 2014 Feb;5(1):17-27. doi: 10.1007/s12975-013-0314-x. Epub 2013 Dec 7. Review.


Disruption of ion homeostasis in the neurogliovascular unit underlies the pathogenesis of ischemic cerebral edema.

Khanna A, Kahle KT, Walcott BP, Gerzanich V, Simard JM.

Transl Stroke Res. 2014 Feb;5(1):3-16. doi: 10.1007/s12975-013-0307-9. Epub 2013 Nov 22. Review.


A novel neuroprotective strategy for ischemic stroke: transient mild acidosis treatment by CO2 inhalation at reperfusion.

Fan YY, Shen Z, He P, Jiang L, Hou WW, Shen Y, Zhang XN, Hu WW, Chen Z.

J Cereb Blood Flow Metab. 2014 Feb;34(2):275-83. doi: 10.1038/jcbfm.2013.193. Epub 2013 Nov 6.


Glibenclamide in cerebral ischemia and stroke.

Simard JM, Sheth KN, Kimberly WT, Stern BJ, del Zoppo GJ, Jacobson S, Gerzanich V.

Neurocrit Care. 2014 Apr;20(2):319-33. doi: 10.1007/s12028-013-9923-1. Review.


Extracellular acidic pH inhibits oligodendrocyte precursor viability, migration, and differentiation.

Jagielska A, Wilhite KD, Van Vliet KJ.

PLoS One. 2013 Sep 30;8(9):e76048. doi: 10.1371/journal.pone.0076048. eCollection 2013.


Loss of Acid sensing ion channel-1a and bicarbonate administration attenuate the severity of traumatic brain injury.

Yin T, Lindley TE, Albert GW, Ahmed R, Schmeiser PB, Grady MS, Howard MA, Welsh MJ.

PLoS One. 2013 Aug 26;8(8):e72379. doi: 10.1371/journal.pone.0072379. eCollection 2013.


Acid-sensing ion channels in pain and disease.

Wemmie JA, Taugher RJ, Kreple CJ.

Nat Rev Neurosci. 2013 Jul;14(7):461-71. doi: 10.1038/nrn3529. Review.

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