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Items: 1 to 20 of 30

1.

The effect of sazetidine-A and other nicotinic ligands on nicotine controlled goal-tracking in female and male rats.

Charntikov S, Falco AM, Fink K, Dwoskin LP, Bevins RA.

Neuropharmacology. 2017 Feb;113(Pt A):354-366. doi: 10.1016/j.neuropharm.2016.10.014. Epub 2016 Oct 17.

PMID:
27765626
2.

Dextromethorphan interactions with histaminergic and serotonergic treatments to reduce nicotine self-administration in rats.

Briggs SA, Hall BJ, Wells C, Slade S, Jaskowski P, Morrison M, Rezvani AH, Rose JE, Levin ED.

Pharmacol Biochem Behav. 2016 Mar;142:1-7. doi: 10.1016/j.pbb.2015.12.004. Epub 2015 Dec 15.

3.

Orthosteric and Allosteric Ligands of Nicotinic Acetylcholine Receptors for Smoking Cessation.

Mohamed TS, Jayakar SS, Hamouda AK.

Front Mol Neurosci. 2015 Nov 25;8:71. doi: 10.3389/fnmol.2015.00071. eCollection 2015. Review.

4.

PKCε phosphorylates α4β2 nicotinic ACh receptors and promotes recovery from desensitization.

Lee AM, Wu DF, Dadgar J, Wang D, McMahon T, Messing RO.

Br J Pharmacol. 2015 Sep;172(17):4430-41. doi: 10.1111/bph.13228. Epub 2015 Jul 26.

5.

Amitifadine, a triple monoamine re-uptake inhibitor, reduces nicotine self-administration in female rats.

Levin ED, Wells C, Johnson JE, Rezvani AH, Bymaster FP, Rose JE.

Eur J Pharmacol. 2015 Oct 5;764:30-7. doi: 10.1016/j.ejphar.2015.06.041. Epub 2015 Jun 20.

6.

Nicotinic receptor modulation to treat alcohol and drug dependence.

Rahman S, Engleman EA, Bell RL.

Front Neurosci. 2015 Jan 15;8:426. doi: 10.3389/fnins.2014.00426. eCollection 2014. Review.

7.

AT-1001: a high-affinity α3β4 nAChR ligand with novel nicotine-suppressive pharmacology.

Cippitelli A, Wu J, Gaiolini KA, Mercatelli D, Schoch J, Gorman M, Ramirez A, Ciccocioppo R, Khroyan TV, Yasuda D, Zaveri NT, Pascual C, Xie XS, Toll L.

Br J Pharmacol. 2015 Apr;172(7):1834-45. doi: 10.1111/bph.13034. Epub 2015 Jan 23.

8.

Decreasing nicotinic receptor activity and the spatial learning impairment caused by the NMDA glutamate antagonist dizocilpine in rats.

Burke DA, Heshmati P, Kholdebarin E, Levin ED.

Eur J Pharmacol. 2014 Oct 15;741:132-9. doi: 10.1016/j.ejphar.2014.07.030. Epub 2014 Jul 24.

9.

Recent developments in novel antidepressants targeting α4β2-nicotinic acetylcholine receptors.

Yu LF, Zhang HK, Caldarone BJ, Eaton JB, Lukas RJ, Kozikowski AP.

J Med Chem. 2014 Oct 23;57(20):8204-23. doi: 10.1021/jm401937a. Epub 2014 Jul 2. Review.

10.

Optimizing treatments for nicotine dependence by increasing cognitive performance during withdrawal.

Ashare RL, Schmidt HD.

Expert Opin Drug Discov. 2014 Jun;9(6):579-94. doi: 10.1517/17460441.2014.908180. Epub 2014 Apr 7. Review.

11.

Dissociation of tolerance and nicotine withdrawal-associated deficits in contextual fear.

Gould TJ, Wilkinson DS, Yildirim E, Blendy JA, Adoff MD.

Brain Res. 2014 Apr 22;1559:1-10. doi: 10.1016/j.brainres.2014.02.038. Epub 2014 Mar 2.

12.

Chronic sazetidine-A maintains anxiolytic effects and slower weight gain following chronic nicotine without maintaining increased density of nicotinic receptors in rodent brain.

Hussmann GP, DeDominicis KE, Turner JR, Yasuda RP, Klehm J, Forcelli PA, Xiao Y, Richardson JR, Sahibzada N, Wolfe BB, Lindstrom J, Blendy JA, Kellar KJ.

J Neurochem. 2014 May;129(4):721-31. doi: 10.1111/jnc.12653. Epub 2014 Feb 7.

13.

Acute activation, desensitization and smoldering activation of human acetylcholine receptors.

Campling BG, Kuryatov A, Lindstrom J.

PLoS One. 2013 Nov 14;8(11):e79653. doi: 10.1371/journal.pone.0079653. eCollection 2013.

14.

Effectiveness of nicotinic agonists as desensitizers at presynaptic α4β2- and α4α5β2-nicotinic acetylcholine receptors.

Wageman CR, Marks MJ, Grady SR.

Nicotine Tob Res. 2014 Mar;16(3):297-305. doi: 10.1093/ntr/ntt146. Epub 2013 Sep 19.

15.

Effects of the sazetidine-a family of compounds on the body temperature in wildtype, nicotinic receptor β2-/- and α7-/- mice.

Levin ED, Sexton HG, Gordon K, Gordon CJ, Xiao Y, Kellar KJ, Yenugonda VM, Liu Y, White MP, Paige M, Brown ML, Rezvani AH.

Eur J Pharmacol. 2013 Oct 15;718(1-3):167-72. doi: 10.1016/j.ejphar.2013.08.037. Epub 2013 Sep 12.

16.

Effects of blockade of α4β2 and α7 nicotinic acetylcholine receptors on cue-induced reinstatement of nicotine-seeking behaviour in rats.

Liu X.

Int J Neuropsychopharmacol. 2014 Jan;17(1):105-16. doi: 10.1017/S1461145713000874. Epub 2013 Aug 19.

17.

Effects of caffeine on alcohol consumption and nicotine self-administration in rats.

Rezvani AH, Sexton HG, Johnson J, Wells C, Gordon K, Levin ED.

Alcohol Clin Exp Res. 2013 Sep;37(9):1609-17. doi: 10.1111/acer.12127. Epub 2013 Apr 23.

18.

Divergent functional effects of sazetidine-a and varenicline during nicotine withdrawal.

Turner JR, Wilkinson DS, Poole RL, Gould TJ, Carlson GC, Blendy JA.

Neuropsychopharmacology. 2013 Sep;38(10):2035-47. doi: 10.1038/npp.2013.105. Epub 2013 Apr 29.

19.

Chemistry and pharmacological studies of 3-alkoxy-2,5-disubstituted-pyridinyl compounds as novel selective α4β2 nicotinic acetylcholine receptor ligands that reduce alcohol intake in rats.

Liu Y, Richardson J, Tran T, Al-Muhtasib N, Xie T, Yenugonda VM, Sexton HG, Rezvani AH, Levin ED, Sahibzada N, Kellar KJ, Brown ML, Xiao Y, Paige M.

J Med Chem. 2013 Apr 11;56(7):3000-11. doi: 10.1021/jm4000374. Epub 2013 Apr 1.

20.

Low dose nicotine and antagonism of β2 subunit containing nicotinic acetylcholine receptors have similar effects on affective behavior in mice.

Anderson SM, Brunzell DH.

PLoS One. 2012;7(11):e48665. doi: 10.1371/journal.pone.0048665. Epub 2012 Nov 7.

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