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Items: 1 to 20 of 27


Toward understanding of the mechanisms of Mediator function in vivo: Focus on the preinitiation complex assembly.

Eychenne T, Werner M, Soutourina J.

Transcription. 2017;8(5):328-342. doi: 10.1080/21541264.2017.1329000. Epub 2017 Aug 25.


Genome-wide characterization of Mediator recruitment, function, and regulation.

Grünberg S, Zentner GE.

Transcription. 2017 May 27;8(3):169-174. doi: 10.1080/21541264.2017.1291082. Epub 2017 Feb 8. Review.


The 9aaTAD Is Exclusive Activation Domain in Gal4.

Piskacek M, Havelka M, Rezacova M, Knight A.

PLoS One. 2017 Jan 5;12(1):e0169261. doi: 10.1371/journal.pone.0169261. eCollection 2017.


Mediator binding to UASs is broadly uncoupled from transcription and cooperative with TFIID recruitment to promoters.

Grünberg S, Henikoff S, Hahn S, Zentner GE.

EMBO J. 2016 Nov 15;35(22):2435-2446. Epub 2016 Oct 20.


The 9aaTAD Transactivation Domains: From Gal4 to p53.

Piskacek M, Havelka M, Rezacova M, Knight A.

PLoS One. 2016 Sep 12;11(9):e0162842. doi: 10.1371/journal.pone.0162842. eCollection 2016.


Structure of a Complete Mediator-RNA Polymerase II Pre-Initiation Complex.

Robinson PJ, Trnka MJ, Bushnell DA, Davis RE, Mattei PJ, Burlingame AL, Kornberg RD.

Cell. 2016 Sep 8;166(6):1411-1422.e16. doi: 10.1016/j.cell.2016.08.050.


Evidence for Multiple Mediator Complexes in Yeast Independently Recruited by Activated Heat Shock Factor.

Anandhakumar J, Moustafa YW, Chowdhary S, Kainth AS, Gross DS.

Mol Cell Biol. 2016 Jun 29;36(14):1943-60. doi: 10.1128/MCB.00005-16. Print 2016 Jul 15.


A Repressor Protein Complex Regulates Leaf Growth in Arabidopsis.

Gonzalez N, Pauwels L, Baekelandt A, De Milde L, Van Leene J, Besbrugge N, Heyndrickx KS, Cuéllar Pérez A, Durand AN, De Clercq R, Van De Slijke E, Vanden Bossche R, Eeckhout D, Gevaert K, Vandepoele K, De Jaeger G, Goossens A, Inzé D.

Plant Cell. 2015 Aug;27(8):2273-87. doi: 10.1105/tpc.15.00006. Epub 2015 Jul 31. Erratum in: Plant Cell. 2016 Mar;28(3):824.


Characterization of ERM transactivation domain binding to the ACID/PTOV domain of the Mediator subunit MED25.

Landrieu I, Verger A, Baert JL, Rucktooa P, Cantrelle FX, Dewitte F, Ferreira E, Lens Z, Villeret V, Monté D.

Nucleic Acids Res. 2015 Aug 18;43(14):7110-21. doi: 10.1093/nar/gkv650. Epub 2015 Jun 29.


Sumoylation controls the timing of Tup1-mediated transcriptional deactivation.

Ng CH, Akhter A, Yurko N, Burgener JM, Rosonina E, Manley JL.

Nat Commun. 2015 Mar 13;6:6610. doi: 10.1038/ncomms7610.


Small molecule probes to target the human Mediator complex.

Phillips AJ, Taatjes DJ.

Isr J Chem. 2013 Aug;53(8):588-595.


A functional portrait of Med7 and the mediator complex in Candida albicans.

Tebbji F, Chen Y, Richard Albert J, Gunsalus KT, Kumamoto CA, Nantel A, Sellam A, Whiteway M.

PLoS Genet. 2014 Nov 6;10(11):e1004770. doi: 10.1371/journal.pgen.1004770. eCollection 2014 Nov.


A sequence-specific transcription activator motif and powerful synthetic variants that bind Mediator using a fuzzy protein interface.

Warfield L, Tuttle LM, Pacheco D, Klevit RE, Hahn S.

Proc Natl Acad Sci U S A. 2014 Aug 26;111(34):E3506-13. doi: 10.1073/pnas.1412088111. Epub 2014 Aug 13.


Significant evidence of linkage for a gene predisposing to colorectal cancer and multiple primary cancers on 22q11.

Teerlink C, Nelson Q, Burt R, Cannon-Albright L.

Clin Transl Gastroenterol. 2014 Feb 27;5:e50. doi: 10.1038/ctg.2014.1.


The TAF9 C-terminal conserved region domain is required for SAGA and TFIID promoter occupancy to promote transcriptional activation.

Saint M, Sawhney S, Sinha I, Singh RP, Dahiya R, Thakur A, Siddharthan R, Natarajan K.

Mol Cell Biol. 2014 May;34(9):1547-63. doi: 10.1128/MCB.01060-13. Epub 2014 Feb 18. Erratum in: Mol Cell Biol. 2017 Jul 14;37(15):.


Discrimination between thermodynamic models of cis-regulation using transcription factor occupancy data.

Zeigler RD, Cohen BA.

Nucleic Acids Res. 2014 Feb;42(4):2224-34. doi: 10.1093/nar/gkt1230. Epub 2013 Nov 27.


Molecular recognition by the KIX domain and its role in gene regulation.

Thakur JK, Yadav A, Yadav G.

Nucleic Acids Res. 2014 Feb;42(4):2112-25. doi: 10.1093/nar/gkt1147. Epub 2013 Nov 18. Review.


The conserved Mediator subunit MDT-15 is required for oxidative stress responses in Caenorhabditis elegans.

Goh GY, Martelli KL, Parhar KS, Kwong AW, Wong MA, Mah A, Hou NS, Taubert S.

Aging Cell. 2014 Feb;13(1):70-9. doi: 10.1111/acel.12154. Epub 2013 Sep 18.


Differential regulation of white-opaque switching by individual subunits of Candida albicans mediator.

Zhang A, Liu Z, Myers LC.

Eukaryot Cell. 2013 Sep;12(9):1293-304. doi: 10.1128/EC.00137-13. Epub 2013 Jul 19.


Mediator recruitment to heat shock genes requires dual Hsf1 activation domains and mediator tail subunits Med15 and Med16.

Kim S, Gross DS.

J Biol Chem. 2013 Apr 26;288(17):12197-213. doi: 10.1074/jbc.M112.449553. Epub 2013 Feb 27.

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