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Items: 13


Breast cancer antiestrogen resistance 3-p130Cas interactions promote adhesion disassembly and invasion in breast cancer cells.

Cross AM, Wilson AL, Guerrero MS, Thomas KS, Bachir AI, Kubow KE, Horwitz AR, Bouton AH.

Oncogene. 2016 Nov 10;35(45):5850-5859. doi: 10.1038/onc.2016.123.


Breast cancer anti-estrogen resistance 3 inhibits transforming growth factor β/Smad signaling and associates with favorable breast cancer disease outcomes.

Guo J, Canaff L, Rajadurai CV, Fils-Aimé N, Tian J, Dai M, Korah J, Villatoro M, Park M, Ali S, Lebrun JJ.

Breast Cancer Res. 2014 Dec 13;16(6):476. doi: 10.1186/s13058-014-0476-9.


Heparanase promotes human gastric cancer cells migration and invasion by increasing Src and p38 phosphorylation expression.

Ma XM, Shen ZH, Liu ZY, Wang F, Hai L, Gao LT, Wang HS.

Int J Clin Exp Pathol. 2014 Aug 15;7(9):5609-21.


Overcoming EMT-associated resistance to anti-cancer drugs via Src/FAK pathway inhibition.

Wilson C, Nicholes K, Bustos D, Lin E, Song Q, Stephan JP, Kirkpatrick DS, Settleman J.

Oncotarget. 2014 Sep 15;5(17):7328-41.


Breast cancer antiestrogen resistance 3 (BCAR3) promotes cell motility by regulating actin cytoskeletal and adhesion remodeling in invasive breast cancer cells.

Wilson AL, Schrecengost RS, Guerrero MS, Thomas KS, Bouton AH.

PLoS One. 2013 Jun 6;8(6):e65678. doi: 10.1371/journal.pone.0065678.


NSP-CAS Protein Complexes: Emerging Signaling Modules in Cancer.

Wallez Y, Mace PD, Pasquale EB, Riedl SJ.

Genes Cancer. 2012 May;3(5-6):382-93. doi: 10.1177/1947601912460050.


Protein tyrosine phosphatase α phosphotyrosyl-789 binds BCAR3 to position Cas for activation at integrin-mediated focal adhesions.

Sun G, Cheng SY, Chen M, Lim CJ, Pallen CJ.

Mol Cell Biol. 2012 Sep;32(18):3776-89. doi: 10.1128/MCB.00214-12.


Breast cancer anti-estrogen resistance 3 (BCAR3) protein augments binding of the c-Src SH3 domain to Crk-associated substrate (p130cas).

Makkinje A, Vanden Borre P, Near RI, Patel PS, Lerner A.

J Biol Chem. 2012 Aug 10;287(33):27703-14. doi: 10.1074/jbc.M112.389981.


NSP-Cas protein structures reveal a promiscuous interaction module in cell signaling.

Mace PD, Wallez Y, Dobaczewska MK, Lee JJ, Robinson H, Pasquale EB, Riedl SJ.

Nat Struct Mol Biol. 2011 Nov 13;18(12):1381-7. doi: 10.1038/nsmb.2152.


Targeting SRC in mucinous ovarian carcinoma.

Matsuo K, Nishimura M, Bottsford-Miller JN, Huang J, Komurov K, Armaiz-Pena GN, Shahzad MM, Stone RL, Roh JW, Sanguino AM, Lu C, Im DD, Rosenshien NB, Sakakibara A, Nagano T, Yamasaki M, Enomoto T, Kimura T, Ram PT, Schmeler KM, Gallick GE, Wong KK, Frumovitz M, Sood AK.

Clin Cancer Res. 2011 Aug 15;17(16):5367-78. doi: 10.1158/1078-0432.CCR-10-3176.


The SRC homology 2 domain protein Shep1 plays an important role in the penetration of olfactory sensory axons into the forebrain.

Wang L, Vervoort V, Wallez Y, Coré N, Cremer H, Pasquale EB.

J Neurosci. 2010 Sep 29;30(39):13201-10. doi: 10.1523/JNEUROSCI.3289-10.2010.


The SH2 domain protein Shep1 regulates the in vivo signaling function of the scaffolding protein Cas.

Roselli S, Wallez Y, Wang L, Vervoort V, Pasquale EB.

Cell Signal. 2010 Nov;22(11):1745-52. doi: 10.1016/j.cellsig.2010.06.015.

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