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Nanoparticle-mediated drug delivery to treat infections in the female reproductive tract: evaluation of experimental systems and the potential for mathematical modeling.

Sims LB, Frieboes HB, Steinbach-Rankins JM.

Int J Nanomedicine. 2018 May 3;13:2709-2727. doi: 10.2147/IJN.S160044. eCollection 2018. Review.


Tunable particles alter macrophage uptake based on combinatorial effects of physical properties.

Garapaty A, Champion JA.

Bioeng Transl Med. 2017 Jan 19;2(1):92-101. doi: 10.1002/btm2.10047. eCollection 2017 Mar.


Nanoparticles in the clinic.

Anselmo AC, Mitragotri S.

Bioeng Transl Med. 2016 Jun 3;1(1):10-29. doi: 10.1002/btm2.10003. eCollection 2016 Mar. Review.


Antimicrobial Activity of Ibuprofen against Cystic Fibrosis-Associated Gram-Negative Pathogens.

Shah PN, Marshall-Batty KR, Smolen JA, Tagaev JA, Chen Q, Rodesney CA, Le HH, Gordon VD, Greenberg DE, Cannon CL.

Antimicrob Agents Chemother. 2018 Feb 23;62(3). pii: e01574-17. doi: 10.1128/AAC.01574-17. Print 2018 Mar.


Distribution of PLGA-modified nanoparticles in 3D cell culture models of hypo-vascularized tumor tissue.

Sims LB, Huss MK, Frieboes HB, Steinbach-Rankins JM.

J Nanobiotechnology. 2017 Oct 5;15(1):67. doi: 10.1186/s12951-017-0298-x.


Physicochemical properties of mucus and their impact on transmucosal drug delivery.

Leal J, Smyth HDC, Ghosh D.

Int J Pharm. 2017 Oct 30;532(1):555-572. doi: 10.1016/j.ijpharm.2017.09.018. Epub 2017 Sep 14. Review.


Oral delivery of biologics using drug-device combinations.

Caffarel-Salvador E, Abramson A, Langer R, Traverso G.

Curr Opin Pharmacol. 2017 Oct;36:8-13. doi: 10.1016/j.coph.2017.07.003. Epub 2017 Aug 2. Review.


Protein nanocages that penetrate airway mucus and tumor tissue.

Huang X, Chisholm J, Zhuang J, Xiao Y, Duncan G, Chen X, Suk JS, Hanes J.

Proc Natl Acad Sci U S A. 2017 Aug 8;114(32):E6595-E6602. doi: 10.1073/pnas.1705407114. Epub 2017 Jul 24.


Heteromer Nanostars by Spontaneous Self-Assembly.

Brocker C, Kim H, Smith D, Barua S.

Nanomaterials (Basel). 2017 May 31;7(6). pii: E127. doi: 10.3390/nano7060127.


A Mouse Intra-Intestinal Infusion Model and its Application to the Study of Nanoparticle Distribution.

Sadio A, Amaral AL, Nunes R, Ricardo S, Sarmento B, Almeida R, Tsukamoto H, das Neves J.

Front Physiol. 2016 Nov 29;7:579. eCollection 2016.


Probing mucin interaction behavior of magnetic nanoparticles.

Boya VN, Lovett R, Setua S, Gandhi V, Nagesh PKB, Khan S, Jaggi M, Yallapu MM, Chauhan SC.

J Colloid Interface Sci. 2017 Feb 15;488:258-268. doi: 10.1016/j.jcis.2016.10.090. Epub 2016 Nov 1.


Mucus-Penetrating Nanosuspensions for Enhanced Delivery of Poorly Soluble Drugs to Mucosal Surfaces.

Yu T, Chisholm J, Choi WJ, Anonuevo A, Pulicare S, Zhong W, Chen M, Fridley C, Lai SK, Ensign LM, Suk JS, Hanes J.

Adv Healthc Mater. 2016 Nov;5(21):2745-2750. doi: 10.1002/adhm.201600599. Epub 2016 Sep 26.


Griffithsin-Modified Electrospun Fibers as a Delivery Scaffold To Prevent HIV Infection.

Grooms TN, Vuong HR, Tyo KM, Malik DA, Sims LB, Whittington CP, Palmer KE, Matoba N, Steinbach-Rankins JM.

Antimicrob Agents Chemother. 2016 Oct 21;60(11):6518-6531. doi: 10.1128/AAC.00956-16. Print 2016 Nov.


Nanoparticles coated with high molecular weight PEG penetrate mucus and provide uniform vaginal and colorectal distribution in vivo.

Maisel K, Reddy M, Xu Q, Chattopadhyay S, Cone R, Ensign LM, Hanes J.

Nanomedicine (Lond). 2016 Jun;11(11):1337-43. doi: 10.2217/nnm-2016-0047. Epub 2016 May 12.


Synthesis and Characterization of Nanocomposite Microparticles (nCmP) for the Treatment of Cystic Fibrosis-Related Infections.

Wang Z, Meenach SA.

Pharm Res. 2016 Aug;33(8):1862-72. doi: 10.1007/s11095-016-1921-5. Epub 2016 Apr 18.


Polymeric nanoparticles in development for treatment of pulmonary infectious diseases.

Lim YH, Tiemann KM, Hunstad DA, Elsabahy M, Wooley KL.

Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2016 Nov;8(6):842-871. doi: 10.1002/wnan.1401. Epub 2016 Mar 25. Review.


PEG modified liposomes containing CRX-601 adjuvant in combination with methylglycol chitosan enhance the murine sublingual immune response to influenza vaccination.

Oberoi HS, Yorgensen YM, Morasse A, Evans JT, Burkhart DJ.

J Control Release. 2016 Feb 10;223:64-74. doi: 10.1016/j.jconrel.2015.11.006. Epub 2015 Nov 6.


Sustained Pulmonary Delivery of a Water-Soluble Antibiotic Without Encapsulating Carriers.

Ong W, Nowak P, Cu Y, Schopf L, Bourassa J, Enlow E, Moskowitz SM, Chen H.

Pharm Res. 2016 Mar;33(3):563-72. doi: 10.1007/s11095-015-1808-x. Epub 2015 Oct 27.


PEGylation as a strategy for improving nanoparticle-based drug and gene delivery.

Suk JS, Xu Q, Kim N, Hanes J, Ensign LM.

Adv Drug Deliv Rev. 2016 Apr 1;99(Pt A):28-51. doi: 10.1016/j.addr.2015.09.012. Epub 2015 Oct 9. Review.


Size selectivity of intestinal mucus to diffusing particulates is dependent on surface chemistry and exposure to lipids.

Yildiz HM, McKelvey CA, Marsac PJ, Carrier RL.

J Drug Target. 2015;23(7-8):768-74. doi: 10.3109/1061186X.2015.1086359.

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