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NPNT is Expressed by Osteoblasts and Mediates Angiogenesis via the Activation of Extracellular Signal-regulated Kinase.

Kuek V, Yang Z, Chim SM, Zhu S, Xu H, Chow ST, Tickner J, Rosen V, Erber W, Li X, An Q, Qian Y, Xu J.

Sci Rep. 2016 Oct 26;6:36210. doi: 10.1038/srep36210.


Myeloma bone disease: Pathophysiology and management.

Silbermann R, Roodman GD.

J Bone Oncol. 2013 Apr 18;2(2):59-69. doi: 10.1016/j.jbo.2013.04.001. Review.


The cast of clasts: catabolism and vascular invasion during bone growth, repair, and disease by osteoclasts, chondroclasts, and septoclasts.

Odgren PR, Witwicka H, Reyes-Gutierrez P.

Connect Tissue Res. 2016 May;57(3):161-74. doi: 10.3109/03008207.2016.1140752.


MMP-9 facilitates selective proteolysis of the histone H3 tail at genes necessary for proficient osteoclastogenesis.

Kim K, Punj V, Kim JM, Lee S, Ulmer TS, Lu W, Rice JC, An W.

Genes Dev. 2016 Jan 15;30(2):208-19. doi: 10.1101/gad.268714.115.


Blocking the ZZ domain of sequestosome1/p62 suppresses myeloma growth and osteoclast formation in vitro and induces dramatic bone formation in myeloma-bearing bones in vivo.

Teramachi J, Silbermann R, Yang P, Zhao W, Mohammad KS, Guo J, Anderson JL, Zhou D, Feng R, Myint KZ, Maertz N, Beumer JH, Eiseman JL, Windle JJ, Xie XQ, Roodman GD, Kurihara N.

Leukemia. 2016 Feb;30(2):390-8. doi: 10.1038/leu.2015.229.


Proteomic Analysis of Estrogen-Mediated Signal Transduction in Osteoclasts Formation.

Xiong Q, Tang P, Gao Y, Zhang L, Ge W.

Biomed Res Int. 2015;2015:596789. doi: 10.1155/2015/596789.


Acute Osteoclast Activity following Subchondral Drilling Is Promoted by Chitosan and Associated with Improved Cartilage Repair Tissue Integration.

Chen G, Sun J, Lascau-Coman V, Chevrier A, Marchand C, Hoemann CD.

Cartilage. 2011 Apr;2(2):173-85. doi: 10.1177/1947603510381096.


EPO promotes bone repair through enhanced cartilaginous callus formation and angiogenesis.

Wan L, Zhang F, He Q, Tsang WP, Lu L, Li Q, Wu Z, Qiu G, Zhou G, Wan C.

PLoS One. 2014 Jul 8;9(7):e102010. doi: 10.1371/journal.pone.0102010. Erratum in: PLoS One. 2014;9(10):e111830.


C/EBPβ mediates osteoclast recruitment by regulating endothelial progenitor cell expression of SDF-1α.

Fu SL, Pang H, Xu JZ, Wu XH.

PLoS One. 2014 Mar 11;9(3):e91217. doi: 10.1371/journal.pone.0091217.


High bone mass in mice lacking Cx37 because of defective osteoclast differentiation.

Pacheco-Costa R, Hassan I, Reginato RD, Davis HM, Bruzzaniti A, Allen MR, Plotkin LI.

J Biol Chem. 2014 Mar 21;289(12):8508-20. doi: 10.1074/jbc.M113.529735.


Mechanisms of multiple myeloma bone disease.

Galson DL, Silbermann R, Roodman GD.

Bonekey Rep. 2012 Aug 1;1:135. doi: 10.1038/bonekey.2012.135.


ATF4 and HIF-1α in bone: an intriguing relationship.

Schipani E, Mangiavini L, Merceron C.

J Bone Miner Res. 2013 Sep;28(9):1866-9. doi: 10.1002/jbmr.2045. No abstract available.


ATF4 promotes bone angiogenesis by increasing VEGF expression and release in the bone environment.

Zhu K, Jiao H, Li S, Cao H, Galson DL, Zhao Z, Zhao X, Lai Y, Fan J, Im HJ, Chen D, Xiao G.

J Bone Miner Res. 2013 Sep;28(9):1870-84. doi: 10.1002/jbmr.1958.


Macrophages in multiple myeloma: emerging concepts and therapeutic implications.

Asimakopoulos F, Kim J, Denu RA, Hope C, Jensen JL, Ollar SJ, Hebron E, Flanagan C, Callander N, Hematti P.

Leuk Lymphoma. 2013 Oct;54(10):2112-21. doi: 10.3109/10428194.2013.778409. Review.


Subchondral pre-solidified chitosan/blood implants elicit reproducible early osteochondral wound-repair responses including neutrophil and stromal cell chemotaxis, bone resorption and repair, enhanced repair tissue integration and delayed matrix deposition.

Lafantaisie-Favreau CH, Guzmán-Morales J, Sun J, Chen G, Harris A, Smith TD, Carli A, Henderson J, Stanish WD, Hoemann CD.

BMC Musculoskelet Disord. 2013 Jan 16;14:27. doi: 10.1186/1471-2474-14-27.


Understanding and targeting osteoclastic activity in prostate cancer bone metastases.

Sottnik JL, Keller ET.

Curr Mol Med. 2013 May;13(4):626-39. Review.


The multifaceted actions of PTHrP in skeletal metastasis.

Soki FN, Park SI, McCauley LK.

Future Oncol. 2012 Jul;8(7):803-17. doi: 10.2217/fon.12.76. Review.


Erythropoietin modulates the structure of bone morphogenetic protein 2-engineered cranial bone.

Sun H, Jung Y, Shiozawa Y, Taichman RS, Krebsbach PH.

Tissue Eng Part A. 2012 Oct;18(19-20):2095-105. doi: 10.1089/ten.TEA.2011.0742.


Skeletal anabolism, PTH, and the bone-vascular axis.

Towler DA.

J Bone Miner Res. 2011 Nov;26(11):2579-82. doi: 10.1002/jbmr.523. No abstract available.


Angiogenesis and multiple myeloma.

Giuliani N, Storti P, Bolzoni M, Palma BD, Bonomini S.

Cancer Microenviron. 2011 Dec;4(3):325-37. doi: 10.1007/s12307-011-0072-9.

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