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Items: 15

1.

Receptor Activity-modifying Protein-directed G Protein Signaling Specificity for the Calcitonin Gene-related Peptide Family of Receptors.

Weston C, Winfield I, Harris M, Hodgson R, Shah A, Dowell SJ, Mobarec JC, Woodlock DA, Reynolds CA, Poyner DR, Watkins HA, Ladds G.

J Biol Chem. 2016 Oct 14;291(42):21925-21944. Epub 2016 Aug 26. Erratum in: J Biol Chem. 2016 Dec 2;291(49):25763.

2.

An allosteric role for receptor activity-modifying proteins in defining GPCR pharmacology.

J Gingell J, Simms J, Barwell J, Poyner DR, Watkins HA, Pioszak AA, Sexton PM, Hay DL.

Cell Discov. 2016 May 17;2:16012. doi: 10.1038/celldisc.2016.12. eCollection 2016. Erratum in: Cell Discov. 2016;2:16020.

3.

Receptor Activity-modifying Proteins 2 and 3 Generate Adrenomedullin Receptor Subtypes with Distinct Molecular Properties.

Watkins HA, Chakravarthy M, Abhayawardana RS, Gingell JJ, Garelja M, Pardamwar M, McElhinney JM, Lathbridge A, Constantine A, Harris PW, Yuen TY, Brimble MA, Barwell J, Poyner DR, Woolley MJ, Conner AC, Pioszak AA, Reynolds CA, Hay DL.

J Biol Chem. 2016 May 27;291(22):11657-75. doi: 10.1074/jbc.M115.688218. Epub 2016 Mar 24.

4.

Chaperoning G protein-coupled receptors: from cell biology to therapeutics.

Tao YX, Conn PM.

Endocr Rev. 2014 Aug;35(4):602-47. doi: 10.1210/er.2013-1121. Epub 2014 Mar 24. Review.

5.

Role of receptor activity modifying protein 1 in function of the calcium sensing receptor in the human TT thyroid carcinoma cell line.

Desai AJ, Roberts DJ, Richards GO, Skerry TM.

PLoS One. 2014 Jan 13;9(1):e85237. doi: 10.1371/journal.pone.0085237. eCollection 2014.

6.

G-protein-coupled receptor 30 interacts with receptor activity-modifying protein 3 and confers sex-dependent cardioprotection.

Lenhart PM, Broselid S, Barrick CJ, Leeb-Lundberg LM, Caron KM.

J Mol Endocrinol. 2013 Jul 3;51(1):191-202. doi: 10.1530/JME-13-0021. Print 2013.

7.

Similarity between class A and class B G-protein-coupled receptors exemplified through calcitonin gene-related peptide receptor modelling and mutagenesis studies.

Vohra S, Taddese B, Conner AC, Poyner DR, Hay DL, Barwell J, Reeves PJ, Upton GJ, Reynolds CA.

J R Soc Interface. 2012 Dec 12;10(79):20120846. doi: 10.1098/rsif.2012.0846. Print 2013 Feb.

8.

AM₁-receptor-dependent protection by intermedin of human vascular and cardiac non-vascular cells from ischaemia-reperfusion injury.

Bell D, Campbell M, Ferguson M, Sayers L, Donaghy L, O'Regan A, Jewhurst V, Harbinson M.

J Physiol. 2012 Mar 1;590(5):1181-97. doi: 10.1113/jphysiol.2011.221895. Epub 2011 Dec 19.

9.

Loss of receptor activity-modifying protein 3 exacerbates cardiac hypertrophy and transition to heart failure in a sex-dependent manner.

Barrick CJ, Lenhart PM, Dackor RT, Nagle E, Caron KM.

J Mol Cell Cardiol. 2012 Jan;52(1):165-74. doi: 10.1016/j.yjmcc.2011.10.021. Epub 2011 Nov 4.

10.

Extracellular loops 1 and 3 and their associated transmembrane regions of the calcitonin receptor-like receptor are needed for CGRP receptor function.

Barwell J, Conner A, Poyner DR.

Biochim Biophys Acta. 2011 Oct;1813(10):1906-16. doi: 10.1016/j.bbamcr.2011.06.005. Epub 2011 Jun 16.

11.

Calcitonin and calcitonin receptor-like receptors: common themes with family B GPCRs?

Barwell J, Gingell JJ, Watkins HA, Archbold JK, Poyner DR, Hay DL.

Br J Pharmacol. 2012 May;166(1):51-65. doi: 10.1111/j.1476-5381.2011.01525.x. Review.

12.

Research resource: Haploinsufficiency of receptor activity-modifying protein-2 (RAMP2) causes reduced fertility, hyperprolactinemia, skeletal abnormalities, and endocrine dysfunction in mice.

Kadmiel M, Fritz-Six K, Pacharne S, Richards GO, Li M, Skerry TM, Caron KM.

Mol Endocrinol. 2011 Jul;25(7):1244-53. doi: 10.1210/me.2010-0400. Epub 2011 May 12.

13.

Ligand binding and activation of the secretin receptor, a prototypic family B G protein-coupled receptor.

Miller LJ, Dong M, Harikumar KG.

Br J Pharmacol. 2012 May;166(1):18-26. doi: 10.1111/j.1476-5381.2011.01463.x. Review.

14.

Regulation of acinar cell function in the pancreas.

Williams JA.

Curr Opin Gastroenterol. 2010 Sep;26(5):478-83. doi: 10.1097/MOG.0b013e32833d11c6. Review.

15.

Role of N-linked glycosylation in biosynthesis, trafficking, and function of the human glucagon-like peptide 1 receptor.

Chen Q, Miller LJ, Dong M.

Am J Physiol Endocrinol Metab. 2010 Jul;299(1):E62-8. doi: 10.1152/ajpendo.00067.2010. Epub 2010 Apr 20.

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