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Items: 1 to 20 of 123


A Label-free Sirtuin 1 Assay based on Droplet-Electrospray Ionization Mass Spectrometry.

Sun S, Buer BC, Marsh EN, Kennedy RT.

Anal Methods. 2016 May 7;8(17):3458-3465.


Pharmacological Strategies to Retard Cardiovascular Aging.

Alfaras I, Di Germanio C, Bernier M, Csiszar A, Ungvari Z, Lakatta EG, de Cabo R.

Circ Res. 2016 May 13;118(10):1626-42. doi: 10.1161/CIRCRESAHA.116.307475. Review.


Dietary proanthocyanidins boost hepatic NAD(+) metabolism and SIRT1 expression and activity in a dose-dependent manner in healthy rats.

Aragonès G, Suárez M, Ardid-Ruiz A, Vinaixa M, Rodríguez MA, Correig X, Arola L, Bladé C.

Sci Rep. 2016 Apr 22;6:24977. doi: 10.1038/srep24977.


Sirtuin 3 (SIRT3) Regulates α-Smooth Muscle Actin (α-SMA) Production through the Succinate Dehydrogenase-G Protein-coupled Receptor 91 (GPR91) Pathway in Hepatic Stellate Cells.

Li YH, Choi DH, Lee EH, Seo SR, Lee S, Cho EH.

J Biol Chem. 2016 May 6;291(19):10277-92. doi: 10.1074/jbc.M115.692244.


Identification of sirtuin 5 inhibitors by ultrafast microchip electrophoresis using nanoliter volume samples.

Guetschow ED, Kumar S, Lombard DB, Kennedy RT.

Anal Bioanal Chem. 2016 Jan;408(3):721-31. doi: 10.1007/s00216-015-9206-0.


The Sirt1 Activators SRT2183 and SRT3025 Inhibit RANKL-Induced Osteoclastogenesis in Bone Marrow-Derived Macrophages and Down-Regulate Sirt3 in Sirt1 Null Cells.

Gurt I, Artsi H, Cohen-Kfir E, Hamdani G, Ben-Shalom G, Feinstein B, El-Haj M, Dresner-Pollak R.

PLoS One. 2015 Jul 30;10(7):e0134391. doi: 10.1371/journal.pone.0134391.


Natural Compounds Modulating Mitochondrial Functions.

Gibellini L, Bianchini E, De Biasi S, Nasi M, Cossarizza A, Pinti M.

Evid Based Complement Alternat Med. 2015;2015:527209. doi: 10.1155/2015/527209. Review.


Structural basis for allosteric, substrate-dependent stimulation of SIRT1 activity by resveratrol.

Cao D, Wang M, Qiu X, Liu D, Jiang H, Yang N, Xu RM.

Genes Dev. 2015 Jun 15;29(12):1316-25. doi: 10.1101/gad.265462.115.


Sirtuins, aging, and cardiovascular risks.

Favero G, Franceschetti L, Rodella LF, Rezzani R.

Age (Dordr). 2015 Aug;37(4):9804. doi: 10.1007/s11357-015-9804-y. Review.


Activation of sirtuin 1 as therapy for the peroxisomal disease adrenoleukodystrophy.

Morató L, Ruiz M, Boada J, Calingasan NY, Galino J, Guilera C, Jové M, Naudí A, Ferrer I, Pamplona R, Serrano M, Portero-Otín M, Beal MF, Fourcade S, Pujol A.

Cell Death Differ. 2015 Nov;22(11):1742-53. doi: 10.1038/cdd.2015.20.


Unbreak my heart: targeting mitochondrial autophagy in diabetic cardiomyopathy.

Kubli DA, Gustafsson ÅB.

Antioxid Redox Signal. 2015 Jun 10;22(17):1527-44. doi: 10.1089/ars.2015.6322. Review.


Sirtuins in epigenetic regulation.

Jing H, Lin H.

Chem Rev. 2015 Mar 25;115(6):2350-75. doi: 10.1021/cr500457h. Review. No abstract available.


Targeting the prodromal stage of Alzheimer's disease: bioenergetic and mitochondrial opportunities.

Caldwell CC, Yao J, Brinton RD.

Neurotherapeutics. 2015 Jan;12(1):66-80. doi: 10.1007/s13311-014-0324-8. Review.


Resveratrol as a therapeutic agent for Alzheimer's disease.

Ma T, Tan MS, Yu JT, Tan L.

Biomed Res Int. 2014;2014:350516. doi: 10.1155/2014/350516. Review.


Leucine Modulates Mitochondrial Biogenesis and SIRT1-AMPK Signaling in C2C12 Myotubes.

Liang C, Curry BJ, Brown PL, Zemel MB.

J Nutr Metab. 2014;2014:239750. doi: 10.1155/2014/239750.


SIRT1 activator (SRT1720) improves the follicle reserve and prolongs the ovarian lifespan of diet-induced obesity in female mice via activating SIRT1 and suppressing mTOR signaling.

Zhou XL, Xu JJ, Ni YH, Chen XC, Zhang HX, Zhang XM, Liu WJ, Luo LL, Fu YC.

J Ovarian Res. 2014 Oct 21;7:97. doi: 10.1186/s13048-014-0097-z.


Roles of resveratrol and other grape-derived polyphenols in Alzheimer's disease prevention and treatment.

Pasinetti GM, Wang J, Ho L, Zhao W, Dubner L.

Biochim Biophys Acta. 2015 Jun;1852(6):1202-8. doi: 10.1016/j.bbadis.2014.10.006. Review.


Phytochemical modulators of mitochondria: the search for chemopreventive agents and supportive therapeutics.

Grabacka MM, Gawin M, Pierzchalska M.

Pharmaceuticals (Basel). 2014 Sep 4;7(9):913-42. doi: 10.3390/ph7090913. Review.


Effects and mechanisms of resveratrol on the amelioration of oxidative stress and hepatic steatosis in KKAy mice.

Zhu W, Chen S, Li Z, Zhao X, Li W, Sun Y, Zhang Z, Ling W, Feng X.

Nutr Metab (Lond). 2014 Aug 12;11:35. doi: 10.1186/1743-7075-11-35.


Small molecule adenosine 5'-monophosphate activated protein kinase (AMPK) modulators and human diseases.

Rana S, Blowers EC, Natarajan A.

J Med Chem. 2015 Jan 8;58(1):2-29. doi: 10.1021/jm401994c. Review.

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