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Items: 1 to 20 of 993


Genome-wide epigenomic profiling for biomarker discovery.

Dirks RA, Stunnenberg HG, Marks H.

Clin Epigenetics. 2016 Nov 21;8:122. Review.


The Genome Conformation As an Integrator of Multi-Omic Data: The Example of Damage Spreading in Cancer.

Tordini F, Aldinucci M, Milanesi L, Liò P, Merelli I.

Front Genet. 2016 Nov 15;7:194.


Lineage-Specific Genome Architecture Links Enhancers and Non-coding Disease Variants to Target Gene Promoters.

Javierre BM, Burren OS, Wilder SP, Kreuzhuber R, Hill SM, Sewitz S, Cairns J, Wingett SW, Várnai C, Thiecke MJ, Burden F, Farrow S, Cutler AJ, Rehnström K, Downes K, Grassi L, Kostadima M, Freire-Pritchett P, Wang F; BLUEPRINT Consortium., Stunnenberg HG, Todd JA, Zerbino DR, Stegle O, Ouwehand WH, Frontini M, Wallace C, Spivakov M, Fraser P.

Cell. 2016 Nov 17;167(5):1369-1384.e19. doi: 10.1016/j.cell.2016.09.037.


Integrative transcriptome network analysis of iPSC-derived neurons from schizophrenia and schizoaffective disorder patients with 22q11.2 deletion.

Lin M, Pedrosa E, Hrabovsky A, Chen J, Puliafito BR, Gilbert SR, Zheng D, Lachman HM.

BMC Syst Biol. 2016 Nov 15;10(1):105.


Emergence of the Noncoding Cancer Genome: A Target of Genetic and Epigenetic Alterations.

Zhou S, Treloar AE, Lupien M.

Cancer Discov. 2016 Nov;6(11):1215-1229. Review.


Capture Hi-C identifies a novel causal gene, IL20RA, in the pan-autoimmune genetic susceptibility region 6q23.

McGovern A, Schoenfelder S, Martin P, Massey J, Duffus K, Plant D, Yarwood A, Pratt AG, Anderson AE, Isaacs JD, Diboll J, Thalayasingam N, Ospelt C, Barton A, Worthington J, Fraser P, Eyre S, Orozco G.

Genome Biol. 2016 Nov 1;17(1):212.


Identification of a RAI1-associated disease network through integration of exome sequencing, transcriptomics, and 3D genomics.

Loviglio MN, Beck CR, White JJ, Leleu M, Harel T, Guex N, Niknejad A, Bi W, Chen ES, Crespo I, Yan J, Charng WL, Gu S, Fang P, Coban-Akdemir Z, Shaw CA, Jhangiani SN, Muzny DM, Gibbs RA, Rougemont J, Xenarios I, Lupski JR, Reymond A.

Genome Med. 2016 Nov 1;8(1):105.


Light-sheet Bayesian microscopy enables deep-cell super-resolution imaging of heterochromatin in live human embryonic stem cells.

Hu YS, Zhu Q, Elkins K, Tse K, Li Y, Fitzpatrick JA, Verma IM, Cang H.

Opt Nanoscopy. 2013;2(1). pii: 7.


Three-dimensional chromosome structures from energy landscape.

Gürsoy G, Liang J.

Proc Natl Acad Sci U S A. 2016 Oct 25;113(43):11991-11993. No abstract available.


Hi-C-constrained physical models of human chromosomes recover functionally-related properties of genome organization.

Di Stefano M, Paulsen J, Lien TG, Hovig E, Micheletti C.

Sci Rep. 2016 Oct 27;6:35985. doi: 10.1038/srep35985.


Insertion of a knockout-first cassette in Ampd1 gene leads to neonatal death by disruption of neighboring genes expression.

Pan Y, Zhang L, Liu Q, Li Y, Guo H, Peng Y, Peng H, Tang B, Hu Z, Zhao J, Xia K, Li JD.

Sci Rep. 2016 Oct 24;6:35970. doi: 10.1038/srep35970.


Dynamic Nucleosome Movement Provides Structural Information of Topological Chromatin Domains in Living Human Cells.

Shinkai S, Nozaki T, Maeshima K, Togashi Y.

PLoS Comput Biol. 2016 Oct 20;12(10):e1005136. doi: 10.1371/journal.pcbi.1005136.


Chromatin accessibility contributes to simultaneous mutations of cancer genes.

Shi Y, Su XB, He KY, Wu BH, Zhang BY, Han ZG.

Sci Rep. 2016 Oct 20;6:35270. doi: 10.1038/srep35270.


Closing the loop: 3C versus DNA FISH.

Giorgetti L, Heard E.

Genome Biol. 2016 Oct 19;17(1):215. Review.


Interactome-transcriptome analysis discovers signatures complementary to GWAS Loci of Type 2 Diabetes.

Li JW, Lee HM, Wang Y, Tong AH, Yip KY, Tsui SK, Lok S, Ozaki R, Luk AO, Kong AP, So WY, Ma RC, Chan JC, Chan TF.

Sci Rep. 2016 Oct 18;6:35228. doi: 10.1038/srep35228.


High-Resolution 4C Reveals Rapid p53-Dependent Chromatin Reorganization of the CDKN1A Locus in Response to Stress.

Millau JF, Wijchers P, Gaudreau L.

PLoS One. 2016 Oct 14;11(10):e0163885. doi: 10.1371/journal.pone.0163885.

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