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Items: 1 to 20 of 138

1.

Integration of Next-Generation Sequencing to Treat Acute Lymphoblastic Leukemia with Targetable Lesions: The St. Jude Children's Research Hospital Approach.

Inaba H, Azzato EM, Mullighan CG.

Front Pediatr. 2017 Dec 4;5:258. doi: 10.3389/fped.2017.00258. eCollection 2017.

2.

Targeting FLT3 Signaling in Childhood Acute Myeloid Leukemia.

Sexauer AN, Tasian SK.

Front Pediatr. 2017 Nov 20;5:248. doi: 10.3389/fped.2017.00248. eCollection 2017. Review.

3.

Skeletal abnormalities detected by SPECT is associated with increased relapse risk in pediatric acute lymphoblastic leukemia.

Zhou F, Zhang M, Han J, Hao J, Xiao Y, Liu Q, Jin R, Mei H.

Oncotarget. 2017 May 23;8(45):79347-79355. doi: 10.18632/oncotarget.18110. eCollection 2017 Oct 3.

4.

US Intergroup Study of Chemotherapy Plus Dasatinib and Allogeneic Stem Cell Transplant in Philadelphia Chromosome Positive ALL.

Ravandi F, Othus M, O'Brien SM, Forman SJ, Ha CS, Wong JYC, Tallman MS, Paietta E, Racevskis J, Uy GL, Horowitz M, Takebe N, Little R, Borate U, Kebriaei P, Kingsbury L, Kantarjian HM, Radich JP, Erba HP, Appelbaum FR.

Blood Adv. 2016 Dec 27;1(3):250-259. doi: 10.1182/bloodadvances.2016001495.

5.

Philadelphia chromosome-like acute lymphoblastic leukemia.

Tasian SK, Loh ML, Hunger SP.

Blood. 2017 Nov 9;130(19):2064-2072. doi: 10.1182/blood-2017-06-743252. Epub 2017 Oct 2. Review.

PMID:
28972016
6.

Novel agents for the treatment of childhood leukemia: an update.

Eryılmaz E, Canpolat C.

Onco Targets Ther. 2017 Jul 4;10:3299-3306. doi: 10.2147/OTT.S126368. eCollection 2017. Review.

8.

PHF6 regulates phenotypic plasticity through chromatin organization within lineage-specific genes.

Soto-Feliciano YM, Bartlebaugh JME, Liu Y, Sánchez-Rivera FJ, Bhutkar A, Weintraub AS, Buenrostro JD, Cheng CS, Regev A, Jacks TE, Young RA, Hemann MT.

Genes Dev. 2017 May 15;31(10):973-989. doi: 10.1101/gad.295857.117. Epub 2017 Jun 12.

9.

JAK/STAT pathway inhibition overcomes IL7-induced glucocorticoid resistance in a subset of human T-cell acute lymphoblastic leukemias.

Delgado-Martin C, Meyer LK, Huang BJ, Shimano KA, Zinter MS, Nguyen JV, Smith GA, Taunton J, Winter SS, Roderick JR, Kelliher MA, Horton TM, Wood BL, Teachey DT, Hermiston ML.

Leukemia. 2017 Dec;31(12):2568-2576. doi: 10.1038/leu.2017.136. Epub 2017 May 9.

10.

Targetable kinase gene fusions in high-risk B-ALL: a study from the Children's Oncology Group.

Reshmi SC, Harvey RC, Roberts KG, Stonerock E, Smith A, Jenkins H, Chen IM, Valentine M, Liu Y, Li Y, Shao Y, Easton J, Payne-Turner D, Gu Z, Tran TH, Nguyen JV, Devidas M, Dai Y, Heerema NA, Carroll AJ 3rd, Raetz EA, Borowitz MJ, Wood BL, Angiolillo AL, Burke MJ, Salzer WL, Zweidler-McKay PA, Rabin KR, Carroll WL, Zhang J, Loh ML, Mullighan CG, Willman CL, Gastier-Foster JM, Hunger SP.

Blood. 2017 Jun 22;129(25):3352-3361. doi: 10.1182/blood-2016-12-758979. Epub 2017 Apr 13.

PMID:
28408464
11.

Targeting the 5T4 oncofetal glycoprotein with an antibody drug conjugate (A1mcMMAF) improves survival in patient-derived xenograft models of acute lymphoblastic leukemia.

McGinn OJ, Krishnan S, Bourquin JP, Sapra P, Dempsey C, Saha V, Stern PL.

Haematologica. 2017 Jun;102(6):1075-1084. doi: 10.3324/haematol.2016.158485. Epub 2017 Mar 24.

12.

Genomic characterization of paediatric acute lymphoblastic leukaemia: an opportunity for precision medicine therapeutics.

Tasian SK, Hunger SP.

Br J Haematol. 2017 Mar;176(6):867-882. doi: 10.1111/bjh.14474. Epub 2016 Dec 16. Review.

PMID:
27984637
13.

Integration of ruxolitinib into dose-intensified therapy targeted against a novel JAK2 F694L mutation in B-precursor acute lymphoblastic leukemia.

Mayfield JR, Czuchlewski DR, Gale JM, Matlawska-Wasowska K, Vasef MA, Nickl C, Pickett G, Ness SA, Winter SS.

Pediatr Blood Cancer. 2017 May;64(5). doi: 10.1002/pbc.26328. Epub 2016 Nov 15.

PMID:
27860260
14.

Antigen-based immunotherapy for the treatment of acute lymphoblastic leukemia: the emerging role of blinatumomab.

Litzow MR.

Immunotargets Ther. 2014 Apr 9;3:79-89. doi: 10.2147/ITT.S37292. eCollection 2014. Review.

15.

CRLF2 over-expression is a poor prognostic marker in children with high risk T-cell acute lymphoblastic leukemia.

Palmi C, Savino AM, Silvestri D, Bronzini I, Cario G, Paganin M, Buldini B, Galbiati M, Muckenthaler MU, Bugarin C, Della Mina P, Nagel S, Barisone E, Casale F, Locatelli F, Lo Nigro L, Micalizzi C, Parasole R, Pession A, Putti MC, Santoro N, Testi AM, Ziino O, Kulozik AE, Zimmermann M, Schrappe M, Villa A, Gaipa G, Basso G, Biondi A, Valsecchi MG, Stanulla M, Conter V, Te Kronnie G, Cazzaniga G.

Oncotarget. 2016 Sep 13;7(37):59260-59272. doi: 10.18632/oncotarget.10610.

16.

Synthesis, biological evaluation, and physicochemical property assessment of 4-substituted 2-phenylaminoquinazolines as Mer tyrosine kinase inhibitors.

Wang SB, Cui MT, Wang XF, Ohkoshi E, Goto M, Yang DX, Li L, Yuan S, Morris-Natschke SL, Lee KH, Xie L.

Bioorg Med Chem. 2016 Jul 1;24(13):3083-3092. doi: 10.1016/j.bmc.2016.05.025. Epub 2016 May 17. Erratum in: Bioorg Med Chem. 2017 May 1;25(9):2676-2678.

17.

Correlation between deletion of the CDKN2 gene and tyrosine kinase inhibitor resistance in adult Philadelphia chromosome-positive acute lymphoblastic leukemia.

Xu N, Li YL, Li X, Zhou X, Cao R, Li H, Li L, Lu ZY, Huang JX, Fan ZP, Huang F, Zhou HS, Zhang S, Liu Z, Zhu HQ, Liu QF, Liu XL.

J Hematol Oncol. 2016 Apr 18;9:40. doi: 10.1186/s13045-016-0270-5.

18.

BIM mediates synergistic killing of B-cell acute lymphoblastic leukemia cells by BCL-2 and MEK inhibitors.

Korfi K, Smith M, Swan J, Somervaille TC, Dhomen N, Marais R.

Cell Death Dis. 2016 Apr 7;7:e2177. doi: 10.1038/cddis.2016.70.

19.

TESTIN Induces Rapid Death and Suppresses Proliferation in Childhood B Acute Lymphoblastic Leukaemia Cells.

Weeks RJ, Ludgate JL, LeMée G, Morison IM.

PLoS One. 2016 Mar 17;11(3):e0151341. doi: 10.1371/journal.pone.0151341. eCollection 2016.

20.

A Case of Dasatinib-Induced Nephrotic Syndrome in a Child with Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia.

Lim YT, Kim YJ, Park YH, Hah JO, Lee JM.

Yonsei Med J. 2016 Mar;57(2):532-3. doi: 10.3349/ymj.2016.57.2.532. No abstract available.

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