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Items: 12

1.

Population Pharmacokinetics Modeling of Unbound Efavirenz, Atazanavir, and Ritonavir in HIV-Infected Subjects With Aging Biomarkers.

Dumond JB, Chen J, Cottrell M, Trezza CR, Prince H, Sykes C, Torrice C, White N, Malone S, Wang R, Patterson KB, Sharpless NE, Forrest A.

CPT Pharmacometrics Syst Pharmacol. 2017 Feb;6(2):128-135. doi: 10.1002/psp4.12151. Epub 2016 Dec 29.

2.

Distinct cellular and molecular environments support aging-related DNA methylation changes in the substantia nigra.

Fasolino M, Liu S, Wang Y, Zhou Z.

Epigenomics. 2017 Jan;9(1):21-31. doi: 10.2217/epi-2016-0084. Epub 2016 Dec 16.

PMID:
27981856
3.

Barriers to the Preclinical Development of Therapeutics that Target Aging Mechanisms.

Burd CE, Gill MS, Niedernhofer LJ, Robbins PD, Austad SN, Barzilai N, Kirkland JL.

J Gerontol A Biol Sci Med Sci. 2016 Nov;71(11):1388-1394. Epub 2016 Aug 16.

4.

Epigenetic regulation of ageing: linking environmental inputs to genomic stability.

Benayoun BA, Pollina EA, Brunet A.

Nat Rev Mol Cell Biol. 2015 Oct;16(10):593-610. doi: 10.1038/nrm4048. Epub 2015 Sep 16. Review.

5.

New molecular targets and lifestyle interventions to delay aging sarcopenia.

Sanchis-Gomar F, Pareja-Galeano H, Mayero S, Perez-Quilis C, Lucia A.

Front Aging Neurosci. 2014 Jul 2;6:156. doi: 10.3389/fnagi.2014.00156. eCollection 2014. Review. No abstract available.

6.

The effects of fucodian on senescence are controlled by the p16INK4a-pRb and p14Arf-p53 pathways in hepatocellular carcinoma and hepatic cell lines.

Min EY, Kim IH, Lee J, Kim EY, Choi YH, Nam TJ.

Int J Oncol. 2014 Jul;45(1):47-56. doi: 10.3892/ijo.2014.2426. Epub 2014 May 8.

7.

Potassium channel activation inhibits proliferation of breast cancer cells by activating a senescence program.

Lansu K, Gentile S.

Cell Death Dis. 2013 Jun 6;4:e652. doi: 10.1038/cddis.2013.174.

8.

Corneal endothelial cells provide evidence of accelerated cellular senescence associated with HIV infection: a case-control study.

Pathai S, Lawn SD, Shiels PG, Weiss HA, Cook C, Wood R, Gilbert CE.

PLoS One. 2013;8(2):e57422. doi: 10.1371/journal.pone.0057422. Epub 2013 Feb 27.

9.

Age-associated gene expression in normal breast tissue mirrors qualitative age-at-incidence patterns for breast cancer.

Pirone JR, D'Arcy M, Stewart DA, Hines WC, Johnson M, Gould MN, Yaswen P, Jerry DJ, Smith Schneider S, Troester MA.

Cancer Epidemiol Biomarkers Prev. 2012 Oct;21(10):1735-44. doi: 10.1158/1055-9965.EPI-12-0451. Epub 2012 Aug 2.

10.

Cellular senescence and tumor suppressor gene p16.

Rayess H, Wang MB, Srivatsan ES.

Int J Cancer. 2012 Apr 15;130(8):1715-25. doi: 10.1002/ijc.27316. Epub 2011 Dec 5. Review.

11.

Predicting cytotoxic T-cell age from multivariate analysis of static and dynamic biomarkers.

Rivet CA, Hill AS, Lu H, Kemp ML.

Mol Cell Proteomics. 2011 Mar;10(3):M110.003921. doi: 10.1074/mcp.M110.003921. Epub 2010 Dec 30.

12.

Real-time in vivo imaging of p16gene expression: a new approach to study senescence stress signaling in living animals.

Ohtani N, Yamakoshi K, Takahashi A, Hara E.

Cell Div. 2010 Jan 14;5:1. doi: 10.1186/1747-1028-5-1.

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