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Items: 20


Dual role of GRK5 in cancer development and progression.

Gambardella J, Franco A, Giudice CD, Fiordelisi A, Cipolletta E, Ciccarelli M, Trimarco B, Iaccarino G, Sorriento D.

Transl Med UniSa. 2016 May 16;14:28-37. eCollection 2016 May.


Calcitonin Receptor-Zonula Occludens-1 Interaction Is Critical for Calcitonin-Stimulated Prostate Cancer Metastasis.

Aljameeli A, Thakkar A, Thomas S, Lakshmikanthan V, Iczkowski KA, Shah GV.

PLoS One. 2016 Mar 2;11(3):e0150090. doi: 10.1371/journal.pone.0150090. eCollection 2016.


A Comprehensive Overview of Skeletal Phenotypes Associated with Alterations in Wnt/β-catenin Signaling in Humans and Mice.

Maupin KA, Droscha CJ, Williams BO.

Bone Res. 2013 Mar 29;1(1):27-71. doi: 10.4248/BR201301004. eCollection 2013 Mar. Review.


The Wnt Co-Receptor Lrp5 Is Required for Cranial Neural Crest Cell Migration in Zebrafish.

Willems B, Tao S, Yu T, Huysseune A, Witten PE, Winkler C.

PLoS One. 2015 Jun 29;10(6):e0131768. doi: 10.1371/journal.pone.0131768. eCollection 2015.


Updating the Wnt pathways.

Yu J, Virshup DM.

Biosci Rep. 2014 Oct 17;34(5). pii: e00142. doi: 10.1042/BSR20140119.


Overlapping and opposing functions of G protein-coupled receptor kinase 2 (GRK2) and GRK5 during heart development.

Philipp M, Berger IM, Just S, Caron MG.

J Biol Chem. 2014 Sep 19;289(38):26119-30. doi: 10.1074/jbc.M114.551952. Epub 2014 Aug 7.


Hepatocyte growth factor (Hgf) stimulates low density lipoprotein receptor-related protein (Lrp) 5/6 phosphorylation and promotes canonical Wnt signaling.

Koraishy FM, Silva C, Mason S, Wu D, Cantley LG.

J Biol Chem. 2014 May 16;289(20):14341-50. doi: 10.1074/jbc.M114.563213. Epub 2014 Apr 1.


Structural basis of GSK-3 inhibition by N-terminal phosphorylation and by the Wnt receptor LRP6.

Stamos JL, Chu ML, Enos MD, Shah N, Weis WI.

Elife. 2014 Mar 18;3:e01998. doi: 10.7554/eLife.01998.


Regulation of Wnt/β-catenin signaling by posttranslational modifications.

Gao C, Xiao G, Hu J.

Cell Biosci. 2014 Mar 4;4(1):13. doi: 10.1186/2045-3701-4-13.


G Protein-coupled receptor kinase-6 interacts with activator of G protein signaling-3 to regulate CXCR2-mediated cellular functions.

Singh V, Raghuwanshi SK, Smith N, Rivers EJ, Richardson RM.

J Immunol. 2014 Mar 1;192(5):2186-94. doi: 10.4049/jimmunol.1301875. Epub 2014 Feb 7.


β-arrestin promotes Wnt-induced low density lipoprotein receptor-related protein 6 (Lrp6) phosphorylation via increased membrane recruitment of Amer1 protein.

Kríz V, Pospíchalová V, Masek J, Kilander MB, Slavík J, Tanneberger K, Schulte G, Machala M, Kozubík A, Behrens J, Bryja V.

J Biol Chem. 2014 Jan 10;289(2):1128-41. doi: 10.1074/jbc.M113.498444. Epub 2013 Nov 21.


Grk5l controls heart development by limiting mTOR signaling during symmetry breaking.

Burkhalter MD, Fralish GB, Premont RT, Caron MG, Philipp M.

Cell Rep. 2013 Aug 29;4(4):625-32. doi: 10.1016/j.celrep.2013.07.036. Epub 2013 Aug 22.


Frizzled and LRP5/6 receptors for Wnt/β-catenin signaling.

MacDonald BT, He X.

Cold Spring Harb Perspect Biol. 2012 Dec 1;4(12). pii: a007880. doi: 10.1101/cshperspect.a007880. Review.


The origin and evolution of G protein-coupled receptor kinases.

Mushegian A, Gurevich VV, Gurevich EV.

PLoS One. 2012;7(3):e33806. doi: 10.1371/journal.pone.0033806. Epub 2012 Mar 19.


Tazarotene-induced gene 1 inhibits prostaglandin E2-stimulated HCT116 colon cancer cell growth.

Tsai FM, Wu CC, Shyu RY, Wang CH, Jiang SY.

J Biomed Sci. 2011 Nov 30;18:88. doi: 10.1186/1423-0127-18-88.


G protein-coupled receptor kinase 5 mediates Tazarotene-induced gene 1-induced growth suppression of human colon cancer cells.

Wu CC, Tsai FM, Shyu RY, Tsai YM, Wang CH, Jiang SY.

BMC Cancer. 2011 May 17;11:175. doi: 10.1186/1471-2407-11-175.


Transmembrane protein 198 promotes LRP6 phosphorylation and Wnt signaling activation.

Liang J, Fu Y, Cruciat CM, Jia S, Wang Y, Tong Z, Tao Q, Ingelfinger D, Boutros M, Meng A, Niehrs C, Wu W.

Mol Cell Biol. 2011 Jul;31(13):2577-90. doi: 10.1128/MCB.05103-11. Epub 2011 May 2.


Aplexone targets the HMG-CoA reductase pathway and differentially regulates arteriovenous angiogenesis.

Choi J, Mouillesseaux K, Wang Z, Fiji HD, Kinderman SS, Otto GW, Geisler R, Kwon O, Chen JN.

Development. 2011 Mar;138(6):1173-81. doi: 10.1242/dev.054049. Epub 2011 Feb 9.


Mitogen-activated protein kinases promote WNT/beta-catenin signaling via phosphorylation of LRP6.

Červenka I, Wolf J, Mašek J, Krejci P, Wilcox WR, Kozubík A, Schulte G, Gutkind JS, Bryja V.

Mol Cell Biol. 2011 Jan;31(1):179-89. doi: 10.1128/MCB.00550-10. Epub 2010 Oct 25.


Development of small molecules targeting the Wnt pathway for the treatment of colon cancer: a high-throughput screening approach.

Chen W, Chen M, Barak LS.

Am J Physiol Gastrointest Liver Physiol. 2010 Aug;299(2):G293-300. doi: 10.1152/ajpgi.00005.2010. Epub 2010 May 27. Review.

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