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Items: 1 to 20 of 27


Identification of a new class of WNT1 inhibitor: Cancer cells migration, G-quadruplex stabilization and target validation.

Chang LC, Chen TC, Chen SJ, Chen CL, Lee CC, Wu SH, Yen Y, Huang HS, Lin JJ.

Oncotarget. 2016 Oct 18;7(42):67986-68001. doi: 10.18632/oncotarget.6622.


Immunobiology of hepatocarcinogenesis: Ways to go or almost there?

Patel P, Schutzer SE, Pyrsopoulos N.

World J Gastrointest Pathophysiol. 2016 Aug 15;7(3):242-55. doi: 10.4291/wjgp.v7.i3.242. Review.


Docosahexaenoic acid inhibits 12-O-tetradecanoylphorbol-13- acetate-induced fascin-1-dependent breast cancer cell migration by suppressing the PKCδ- and Wnt-1/β-catenin-mediated pathways.

Lii CK, Chang JW, Chen JJ, Chen HW, Liu KL, Yeh SL, Wang TS, Liu SH, Tsai CH, Li CC.

Oncotarget. 2016 May 3;7(18):25162-79. doi: 10.18632/oncotarget.7301.


The evolving roles of canonical WNT signaling in stem cells and tumorigenesis: implications in targeted cancer therapies.

Yang K, Wang X, Zhang H, Wang Z, Nan G, Li Y, Zhang F, Mohammed MK, Haydon RC, Luu HH, Bi Y, He TC.

Lab Invest. 2016 Feb;96(2):116-36. doi: 10.1038/labinvest.2015.144. Epub 2015 Nov 30.


Targeting Wnt signaling in colorectal cancer. A Review in the Theme: Cell Signaling: Proteins, Pathways and Mechanisms.

Novellasdemunt L, Antas P, Li VS.

Am J Physiol Cell Physiol. 2015 Oct 15;309(8):C511-21. doi: 10.1152/ajpcell.00117.2015. Epub 2015 Aug 19. Review.


Tankyrase inhibitors attenuate WNT/β-catenin signaling and inhibit growth of hepatocellular carcinoma cells.

Ma L, Wang X, Jia T, Wei W, Chua MS, So S.

Oncotarget. 2015 Sep 22;6(28):25390-401. doi: 10.18632/oncotarget.4455.


Prevention of hepatocellular carcinoma by correction of metabolic abnormalities: Role of statins and metformin.

Ampuero J, Romero-Gomez M.

World J Hepatol. 2015 May 18;7(8):1105-11. doi: 10.4254/wjh.v7.i8.1105. Review.


Genome-wide ChIP-seq analysis of TCF4 binding regions in colorectal cancer cells.

Chen C, Lu Y, Liu J, Li L, Zhao N, Lin B.

Int J Clin Exp Med. 2014 Nov 15;7(11):4253-9. eCollection 2014.


Targeting the Wnt signaling pathways in pulmonary arterial hypertension.

de Jesus Perez V, Yuan K, Alastalo TP, Spiekerkoetter E, Rabinovitch M.

Drug Discov Today. 2014 Aug;19(8):1270-6. doi: 10.1016/j.drudis.2014.06.014. Epub 2014 Jun 20. Review.


Oral epithelial stem cells - implications in normal development and cancer metastasis.

Papagerakis S, Pannone G, Zheng L, About I, Taqi N, Nguyen NP, Matossian M, McAlpin B, Santoro A, McHugh J, Prince ME, Papagerakis P.

Exp Cell Res. 2014 Jul 15;325(2):111-29. doi: 10.1016/j.yexcr.2014.04.021. Epub 2014 May 5. Review.


Inhibition of cancer cell migration and invasion through suppressing the Wnt1-mediating signal pathway by G-quadruplex structure stabilizers.

Wang JM, Huang FC, Kuo MH, Wang ZF, Tseng TY, Chang LC, Yen SJ, Chang TC, Lin JJ.

J Biol Chem. 2014 May 23;289(21):14612-23. doi: 10.1074/jbc.M114.548230. Epub 2014 Apr 8.


Inactivation of Wnt signaling by a human antibody that recognizes the heparan sulfate chains of glypican-3 for liver cancer therapy.

Gao W, Kim H, Feng M, Phung Y, Xavier CP, Rubin JS, Ho M.

Hepatology. 2014 Aug;60(2):576-87. doi: 10.1002/hep.26996. Epub 2014 Jun 18.


Cornelia de Lange Syndrome: NIPBL haploinsufficiency downregulates canonical Wnt pathway in zebrafish embryos and patients fibroblasts.

Pistocchi A, Fazio G, Cereda A, Ferrari L, Bettini LR, Messina G, Cotelli F, Biondi A, Selicorni A, Massa V.

Cell Death Dis. 2013 Oct 17;4:e866. doi: 10.1038/cddis.2013.371.


Role of two single nucleotide polymorphisms in secreted frizzled related protein 1 and bladder cancer risk.

Rogler A, Hoja S, Socher E, Nolte E, Wach S, Wieland W, Hofstädter F, Goebell PJ, Wullich B, Hartmann A, Stoehr R.

Int J Clin Exp Pathol. 2013 Sep 15;6(10):1984-98. eCollection 2013.


β-Catenin knockdown in liver tumor cells by a cell permeable gamma guanidine-based peptide nucleic acid.

Delgado E, Bahal R, Yang J, Lee JM, Ly DH, Monga SP.

Curr Cancer Drug Targets. 2013 Oct;13(8):867-78.


The noncoding RNA expression profile and the effect of lncRNA AK126698 on cisplatin resistance in non-small-cell lung cancer cell.

Yang Y, Li H, Hou S, Hu B, Liu J, Wang J.

PLoS One. 2013 May 31;8(5):e65309. doi: 10.1371/journal.pone.0065309. Print 2013.


Dynamic changes in 5-hydroxymethylation signatures underpin early and late events in drug exposed liver.

Thomson JP, Hunter JM, Lempiäinen H, Müller A, Terranova R, Moggs JG, Meehan RR.

Nucleic Acids Res. 2013 Jun;41(11):5639-54. doi: 10.1093/nar/gkt232. Epub 2013 Apr 17.


Targeting Wnt pathways in disease.

Zimmerman ZF, Moon RT, Chien AJ.

Cold Spring Harb Perspect Biol. 2012 Nov 1;4(11). pii: a008086. doi: 10.1101/cshperspect.a008086. Review.


Hedgehog signaling pathway mediates invasion and metastasis of hepatocellular carcinoma via ERK pathway.

Lu JT, Zhao WD, He W, Wei W.

Acta Pharmacol Sin. 2012 May;33(5):691-700. doi: 10.1038/aps.2012.24. Epub 2012 Apr 30.

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