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TP53 gene mutation analysis in chronic lymphocytic leukemia by nanopore MinION sequencing.

Minervini CF, Cumbo C, Orsini P, Brunetti C, Anelli L, Zagaria A, Minervini A, Casieri P, Coccaro N, Tota G, Impera L, Giordano A, Specchia G, Albano F.

Diagn Pathol. 2016 Oct 10;11(1):96.


p53 in the game of transposons.

Wylie A, Jones AE, Abrams JM.

Bioessays. 2016 Nov;38(11):1111-1116. doi: 10.1002/bies.201600115. Epub 2016 Sep 19.


SMG7 is a critical regulator of p53 stability and function in DNA damage stress response.

Luo H, Cowen L, Yu G, Jiang W, Tang Y.

Cell Discov. 2016 Jan 19;2:15042. doi: 10.1038/celldisc.2015.42. eCollection 2016.


Thymic and Postthymic Regulation of Naïve CD4(+) T-Cell Lineage Fates in Humans and Mice Models.

Belizário JE, Brandão W, Rossato C, Peron JP.

Mediators Inflamm. 2016;2016:9523628. doi: 10.1155/2016/9523628. Epub 2016 May 30. Review.


The p53-like Protein CEP-1 Is Required for Meiotic Fidelity in C. elegans.

Mateo AR, Kessler Z, Jolliffe AK, McGovern O, Yu B, Nicolucci A, Yanowitz JL, Derry WB.

Curr Biol. 2016 May 9;26(9):1148-58. doi: 10.1016/j.cub.2016.03.036. Epub 2016 Apr 14.


A platform for interrogating cancer-associated p53 alleles.

D'Brot A, Kurtz P, Regan E, Jakubowski B, Abrams JM.

Oncogene. 2017 Jan 12;36(2):286-291. doi: 10.1038/onc.2016.48. Epub 2016 Mar 21.


PACS-2 mediates the ATM and NF-κB-dependent induction of anti-apoptotic Bcl-xL in response to DNA damage.

Barroso-González J, Auclair S, Luan S, Thomas L, Atkins KM, Aslan JE, Thomas LL, Zhao J, Zhao Y, Thomas G.

Cell Death Differ. 2016 Sep 1;23(9):1448-57. doi: 10.1038/cdd.2016.23. Epub 2016 Mar 4.


Dissecting protein architecture with communication blocks and communicating segment pairs.

Karami Y, Laine E, Carbone A.

BMC Bioinformatics. 2016 Jan 20;17 Suppl 2:13. doi: 10.1186/s12859-015-0855-y.


The p53-Mdm2 interaction and the E3 ligase activity of Mdm2/Mdm4 are conserved from lampreys to humans.

Coffill CR, Lee AP, Siau JW, Chee SM, Joseph TL, Tan YS, Madhumalar A, Tay BH, Brenner S, Verma CS, Ghadessy FJ, Venkatesh B, Lane DP.

Genes Dev. 2016 Feb 1;30(3):281-92. doi: 10.1101/gad.274118.115. Epub 2016 Jan 21.


p53 genes function to restrain mobile elements.

Wylie A, Jones AE, D'Brot A, Lu WJ, Kurtz P, Moran JV, Rakheja D, Chen KS, Hammer RE, Comerford SA, Amatruda JF, Abrams JM.

Genes Dev. 2016 Jan 1;30(1):64-77. doi: 10.1101/gad.266098.115. Epub 2015 Dec 23.


Evolutionary determinants of cancer.

Greaves M.

Cancer Discov. 2015 Aug;5(8):806-20. doi: 10.1158/2159-8290.CD-15-0439. Epub 2015 Jul 20. Review.


Tumor-suppressive p53 Signaling Empowers Metastatic Inhibitor KLF17-dependent Transcription to Overcome Tumorigenesis in Non-small Cell Lung Cancer.

Ali A, Bhatti MZ, Shah AS, Duong HQ, Alkreathy HM, Mohammad SF, Khan RA, Ahmad A.

J Biol Chem. 2015 Aug 28;290(35):21336-51. doi: 10.1074/jbc.M114.635730. Epub 2015 Apr 24.


Evolution of p53 transactivation specificity through the lens of a yeast-based functional assay.

Lion M, Raimondi I, Donati S, Jousson O, Ciribilli Y, Inga A.

PLoS One. 2015 Feb 10;10(2):e0116177. doi: 10.1371/journal.pone.0116177. eCollection 2015.


The p53 control of apoptosis and proliferation: lessons from Drosophila.

Mollereau B, Ma D.

Apoptosis. 2014 Oct;19(10):1421-9. doi: 10.1007/s10495-014-1035-7. Review.


The multifunctional sorting protein PACS-2 regulates SIRT1-mediated deacetylation of p53 to modulate p21-dependent cell-cycle arrest.

Atkins KM, Thomas LL, Barroso-González J, Thomas L, Auclair S, Yin J, Kang H, Chung JH, Dikeakos JD, Thomas G.

Cell Rep. 2014 Sep 11;8(5):1545-57. doi: 10.1016/j.celrep.2014.07.049. Epub 2014 Aug 21.


Ribosomal protein-Mdm2-p53 pathway coordinates nutrient stress with lipid metabolism by regulating MCD and promoting fatty acid oxidation.

Liu Y, He Y, Jin A, Tikunov AP, Zhou L, Tollini LA, Leslie P, Kim TH, Li LO, Coleman RA, Gu Z, Chen YQ, Macdonald JM, Graves LM, Zhang Y.

Proc Natl Acad Sci U S A. 2014 Jun 10;111(23):E2414-22. doi: 10.1073/pnas.1315605111. Epub 2014 May 28.


Loss of function tp53 mutations do not accelerate the onset of myc-induced T-cell acute lymphoblastic leukaemia in the zebrafish.

Gutierrez A, Feng H, Stevenson K, Neuberg DS, Calzada O, Zhou Y, Langenau DM, Look AT.

Br J Haematol. 2014 Jul;166(1):84-90. doi: 10.1111/bjh.12851. Epub 2014 Apr 2.


p53 activity is selectively licensed in the Drosophila stem cell compartment.

Wylie A, Lu WJ, D'Brot A, Buszczak M, Abrams JM.

Elife. 2014 Mar 11;3:e01530. doi: 10.7554/eLife.01530.


A p53 enhancer region regulates target genes through chromatin conformations in cis and in trans.

Link N, Kurtz P, O'Neal M, Garcia-Hughes G, Abrams JM.

Genes Dev. 2013 Nov 15;27(22):2433-8. doi: 10.1101/gad.225565.113.


Structure and stability insights into tumour suppressor p53 evolutionary related proteins.

Pagano B, Jama A, Martinez P, Akanho E, Bui TT, Drake AF, Fraternali F, Nikolova PV.

PLoS One. 2013 Oct 4;8(10):e76014. doi: 10.1371/journal.pone.0076014. eCollection 2013.

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