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Items: 1 to 20 of 45

1.

Inflammatory osteolysis: a conspiracy against bone.

Mbalaviele G, Novack DV, Schett G, Teitelbaum SL.

J Clin Invest. 2017 Jun 1;127(6):2030-2039. doi: 10.1172/JCI93356. Epub 2017 Jun 1. Review.

2.

RANKL cytokine enhances TNF-induced osteoclastogenesis independently of TNF receptor associated factor (TRAF) 6 by degrading TRAF3 in osteoclast precursors.

Yao Z, Lei W, Duan R, Li Y, Luo L, Boyce BF.

J Biol Chem. 2017 Jun 16;292(24):10169-10179. doi: 10.1074/jbc.M116.771816. Epub 2017 Apr 24.

PMID:
28438834
3.

Def6 Restrains Osteoclastogenesis and Inflammatory Bone Resorption.

Binder N, Miller C, Yoshida M, Inoue K, Nakano S, Hu X, Ivashkiv LB, Schett G, Pernis A, Goldring SR, Ross FP, Zhao B.

J Immunol. 2017 May 1;198(9):3436-3447. doi: 10.4049/jimmunol.1601716. Epub 2017 Mar 17.

PMID:
28314855
4.

Clomipramine causes osteoporosis by promoting osteoclastogenesis via E3 ligase Itch, which is prevented by Zoledronic acid.

Li X, Sun W, Li J, Wang M, Zhang H, Pei L, Boyce BF, Wang Z, Xing L.

Sci Rep. 2017 Feb 1;7:41358. doi: 10.1038/srep41358.

5.

Development of an efficient screening system to identify novel bone metabolism-related genes using the exchangeable gene trap mutagenesis mouse models.

Kurogi S, Sekimoto T, Funamoto T, Ota T, Nakamura S, Nagai T, Nakahara M, Yoshinobu K, Araki K, Araki M, Chosa E.

Sci Rep. 2017 Jan 20;7:40692. doi: 10.1038/srep40692.

6.

Editorial: Inflammatory Osteoclasts: A Different Breed of Bone Eaters?

Novack DV.

Arthritis Rheumatol. 2016 Dec;68(12):2834-2836. doi: 10.1002/art.39835. No abstract available.

PMID:
27575608
7.

Osteoclasts-Key Players in Skeletal Health and Disease.

Novack DV, Mbalaviele G.

Microbiol Spectr. 2016 Jun;4(3). doi: 10.1128/microbiolspec.MCHD-0011-2015. Review.

8.

Lymphatic endothelial cells efferent to inflamed joints produce iNOS and inhibit lymphatic vessel contraction and drainage in TNF-induced arthritis in mice.

Liang Q, Ju Y, Chen Y, Wang W, Li J, Zhang L, Xu H, Wood RW, Schwarz EM, Boyce BF, Wang Y, Xing L.

Arthritis Res Ther. 2016 Mar 12;18:62. doi: 10.1186/s13075-016-0963-8.

9.

TLR4 drives the pathogenesis of acquired cholesteatoma by promoting local inflammation and bone destruction.

Si Y, Chen YB, Chen SJ, Zheng YQ, Liu X, Liu Y, Jiang HL, Xu G, Li ZH, Huang QH, Xiong H, Zhang ZG.

Sci Rep. 2015 Dec 7;5:16683. doi: 10.1038/srep16683.

10.

CD44 deficiency inhibits unloading-induced cortical bone loss through downregulation of osteoclast activity.

Li Y, Zhong G, Sun W, Zhao C, Zhang P, Song J, Zhao D, Jin X, Li Q, Ling S, Li Y.

Sci Rep. 2015 Nov 4;5:16124. doi: 10.1038/srep16124.

11.

TNF Induction of NF-κB RelB Enhances RANKL-Induced Osteoclastogenesis by Promoting Inflammatory Macrophage Differentiation but also Limits It through Suppression of NFATc1 Expression.

Zhao Z, Hou X, Yin X, Li Y, Duan R, Boyce BF, Yao Z.

PLoS One. 2015 Aug 19;10(8):e0135728. doi: 10.1371/journal.pone.0135728. eCollection 2015.

12.

Mice Deficient in NF-κB p50 and p52 or RANK Have Defective Growth Plate Formation and Post-natal Dwarfism.

Xing L, Chen D, Boyce BF.

Bone Res. 2013 Dec 31;1(4):336-45. doi: 10.4248/BR201304004. eCollection 2013 Dec.

13.

NF-κB-Mediated Regulation of Osteoclastogenesis.

Boyce BF, Xiu Y, Li J, Xing L, Yao Z.

Endocrinol Metab (Seoul). 2015 Mar 27;30(1):35-44. doi: 10.3803/EnM.2015.30.1.35. Review.

14.

Loss of SH3 domain-binding protein 2 function suppresses bone destruction in tumor necrosis factor-driven and collagen-induced arthritis in mice.

Mukai T, Gallant R, Ishida S, Kittaka M, Yoshitaka T, Fox DA, Morita Y, Nishida K, Rottapel R, Ueki Y.

Arthritis Rheumatol. 2015 Mar;67(3):656-67. doi: 10.1002/art.38975.

15.

Biology of the RANKL-RANK-OPG System in Immunity, Bone, and Beyond.

Walsh MC, Choi Y.

Front Immunol. 2014 Oct 20;5:511. doi: 10.3389/fimmu.2014.00511. eCollection 2014. Review.

16.

p100/IκBδ sequesters and inhibits NF-κB through kappaBsome formation.

Tao Z, Fusco A, Huang DB, Gupta K, Young Kim D, Ware CF, Van Duyne GD, Ghosh G.

Proc Natl Acad Sci U S A. 2014 Nov 11;111(45):15946-51. doi: 10.1073/pnas.1408552111. Epub 2014 Oct 27.

17.

Wnt4 signaling prevents skeletal aging and inflammation by inhibiting nuclear factor-κB.

Yu B, Chang J, Liu Y, Li J, Kevork K, Al-Hezaimi K, Graves DT, Park NH, Wang CY.

Nat Med. 2014 Sep;20(9):1009-17. doi: 10.1038/nm.3586. Epub 2014 Aug 10. Erratum in: Nat Med. 2015 Sep;21(9):1101.

18.

SH3BP2 cherubism mutation potentiates TNF-α-induced osteoclastogenesis via NFATc1 and TNF-α-mediated inflammatory bone loss.

Mukai T, Ishida S, Ishikawa R, Yoshitaka T, Kittaka M, Gallant R, Lin YL, Rottapel R, Brotto M, Reichenberger EJ, Ueki Y.

J Bone Miner Res. 2014 Dec;29(12):2618-35. doi: 10.1002/jbmr.2295.

19.

NOTCH inhibits osteoblast formation in inflammatory arthritis via noncanonical NF-κB.

Zhang H, Hilton MJ, Anolik JH, Welle SL, Zhao C, Yao Z, Li X, Wang Z, Boyce BF, Xing L.

J Clin Invest. 2014 Jul;124(7):3200-14. doi: 10.1172/JCI68901. Epub 2014 Jun 2.

20.

Critical role for inflammasome-independent IL-1β production in osteomyelitis.

Lukens JR, Gross JM, Calabrese C, Iwakura Y, Lamkanfi M, Vogel P, Kanneganti TD.

Proc Natl Acad Sci U S A. 2014 Jan 21;111(3):1066-71. doi: 10.1073/pnas.1318688111. Epub 2014 Jan 6.

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