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Items: 1 to 20 of 316

1.

Metformin and berberine, two versatile drugs in treatment of common metabolic diseases.

Wang H, Zhu C, Ying Y, Luo L, Huang D, Luo Z.

Oncotarget. 2017 Sep 11;9(11):10135-10146. doi: 10.18632/oncotarget.20807. eCollection 2018 Feb 9. Review.

2.

Development of an Injectable Slow-Release Metformin Formulation and Evaluation of Its Potential Antitumor Effects.

Baldassari S, Solari A, Zuccari G, Drava G, Pastorino S, Fucile C, Marini V, Daga A, Pattarozzi A, Ratto A, Ferrari A, Mattioli F, Barbieri F, Caviglioli G, Florio T.

Sci Rep. 2018 Mar 2;8(1):3929. doi: 10.1038/s41598-018-22054-w.

3.

Hypoxia Pathway Proteins As Central Mediators of Metabolism in the Tumor Cells and Their Microenvironment.

Sormendi S, Wielockx B.

Front Immunol. 2018 Jan 29;9:40. doi: 10.3389/fimmu.2018.00040. eCollection 2018. Review.

4.

Metformin and cancer: An existing drug for cancer prevention and therapy.

Zi F, Zi H, Li Y, He J, Shi Q, Cai Z.

Oncol Lett. 2018 Jan;15(1):683-690. doi: 10.3892/ol.2017.7412. Epub 2017 Nov 14.

5.
6.

Antitumor effects of metformin are a result of inhibiting nuclear factor kappa B nuclear translocation in esophageal squamous cell carcinoma.

Sekino N, Kano M, Matsumoto Y, Sakata H, Akutsu Y, Hanari N, Murakami K, Toyozumi T, Takahashi M, Otsuka R, Yokoyama M, Shiraishi T, Okada K, Hoshino I, Iida K, Akimoto AK, Matsubara H.

Cancer Sci. 2018 Apr;109(4):1066-1074. doi: 10.1111/cas.13523. Epub 2018 Feb 26.

7.

Cell death-based treatment of neuroblastoma.

Valter K, Zhivotovsky B, Gogvadze V.

Cell Death Dis. 2018 Jan 25;9(2):113. doi: 10.1038/s41419-017-0060-1. Review.

9.

Effects of metformin on colorectal cancer stem cells depend on alterations in glutamine metabolism.

Kim JH, Lee KJ, Seo Y, Kwon JH, Yoon JP, Kang JY, Lee HJ, Park SJ, Hong SP, Cheon JH, Kim WH, Ii Kim T.

Sci Rep. 2018 Jan 11;8(1):409. doi: 10.1038/s41598-017-18762-4.

10.

Metformin sensitizes lung cancer cells to treatment by the tyrosine kinase inhibitor erlotinib.

Wang X, Chen K, Yu Y, Xiang Y, Kim JH, Gong W, Huang J, Shi G, Li Q, Zhou M, Sayers T, Tewary P, Gao B, Wang JM.

Oncotarget. 2017 Nov 21;8(65):109068-109078. doi: 10.18632/oncotarget.22596. eCollection 2017 Dec 12.

11.

Survival benefits in colorectal adenocarcinoma with the use of metformin among a black diabetic inner city population.

Zhu RC, Rattanakorn K, Pham S, Mallam D, McIntyre T, Salifu MO, Youssef I, McFarlane SI, Vignesh S.

Colorectal Cancer. 2017;6(1):33-41. doi: 10.2217/crc-2017-0001. Epub 2017 Jun 21.

12.

Noncanonical agonist PPARγ ligands modulate the response to DNA damage and sensitize cancer cells to cytotoxic chemotherapy.

Khandekar MJ, Banks AS, Laznik-Bogoslavski D, White JP, Choi JH, Kazak L, Lo JC, Cohen P, Wong KK, Kamenecka TM, Griffin PR, Spiegelman BM.

Proc Natl Acad Sci U S A. 2018 Jan 16;115(3):561-566. doi: 10.1073/pnas.1717776115. Epub 2018 Jan 2.

PMID:
29295932
13.

Therapeutic strategies against cancer stem cells in human colorectal cancer.

Szaryńska M, Olejniczak A, Kobiela J, Spychalski P, Kmieć Z.

Oncol Lett. 2017 Dec;14(6):7653-7668. doi: 10.3892/ol.2017.7261. Epub 2017 Oct 23.

14.

Drug Resistance Driven by Cancer Stem Cells and Their Niche.

Prieto-Vila M, Takahashi RU, Usuba W, Kohama I, Ochiya T.

Int J Mol Sci. 2017 Dec 1;18(12). pii: E2574. doi: 10.3390/ijms18122574. Review.

15.

Metabolic modulation of Ewing sarcoma cells inhibits tumor growth and stem cell properties.

Dasgupta A, Trucco M, Rainusso N, Bernardi RJ, Shuck R, Kurenbekova L, Loeb DM, Yustein JT.

Oncotarget. 2017 Aug 24;8(44):77292-77308. doi: 10.18632/oncotarget.20467. eCollection 2017 Sep 29.

16.

Attenuation of CD4+CD25+ Regulatory T Cells in the Tumor Microenvironment by Metformin, a Type 2 Diabetes Drug.

Kunisada Y, Eikawa S, Tomonobu N, Domae S, Uehara T, Hori S, Furusawa Y, Hase K, Sasaki A, Udono H.

EBioMedicine. 2017 Nov;25:154-164. doi: 10.1016/j.ebiom.2017.10.009. Epub 2017 Oct 16.

17.

Downregulation of Rab27A contributes to metformin-induced suppression of breast cancer stem cells.

Feng F, Zhang J, Fan X, Yuan F, Jiang Y, Lv R, Ma Y.

Oncol Lett. 2017 Sep;14(3):2947-2953. doi: 10.3892/ol.2017.6542. Epub 2017 Jul 8.

18.

Colocynth Extracts Prevent Epithelial to Mesenchymal Transition and Stemness of Breast Cancer Cells.

Chowdhury K, Sharma A, Kumar S, Gunjan GK, Nag A, Mandal CC.

Front Pharmacol. 2017 Sep 5;8:593. doi: 10.3389/fphar.2017.00593. eCollection 2017.

19.

The Clinical Effect of Metformin on the Survival of Lung Cancer Patients with Diabetes: A Comprehensive Systematic Review and Meta-analysis of Retrospective Studies.

Cao X, Wen ZS, Wang XD, Li Y, Liu KY, Wang X.

J Cancer. 2017 Aug 2;8(13):2532-2541. doi: 10.7150/jca.19750. eCollection 2017.

20.

Aberrant Signaling Pathways in T-Cell Acute Lymphoblastic Leukemia.

Bongiovanni D, Saccomani V, Piovan E.

Int J Mol Sci. 2017 Sep 5;18(9). pii: E1904. doi: 10.3390/ijms18091904. Review.

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