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Items: 1 to 20 of 182


Dose-dependent effects of gamma radiation on the early zebrafish development and gene expression.

Hurem S, Martín LM, Brede DA, Skjerve E, Nourizadeh-Lillabadi R, Lind OC, Christensen T, Berg V, Teien HC, Salbu B, Oughton DH, Aleström P, Lyche JL.

PLoS One. 2017 Jun 19;12(6):e0179259. doi: 10.1371/journal.pone.0179259. eCollection 2017.


The cancer theory of pulmonary arterial hypertension.

Boucherat O, Vitry G, Trinh I, Paulin R, Provencher S, Bonnet S.

Pulm Circ. 2017 Apr-Jun;7(2):285-299. doi: 10.1177/2045893217701438. Epub 2017 Mar 27.


Akt3 is responsible for the survival and proliferation of embryonic stem cells.

Wang L, Huang D, Jiang Z, Luo Y, Norris C, Zhang M, Tian X, Tang Y.

Biol Open. 2017 Jun 15;6(6):850-861. doi: 10.1242/bio.024505.


Apigenin enhances the cisplatin cytotoxic effect through p53-modulated apoptosis.

Liu R, Ji P, Liu B, Qiao H, Wang X, Zhou L, Deng T, Ba Y.

Oncol Lett. 2017 Feb;13(2):1024-1030. doi: 10.3892/ol.2016.5495. Epub 2016 Dec 14.


Coumarin-chalcone hybrid instigates DNA damage by minor groove binding and stabilizes p53 through post translational modifications.

Ashraf R, Hamidullah, Hasanain M, Pandey P, Maheshwari M, Singh LR, Siddiqui MQ, Konwar R, Sashidhara KV, Sarkar J.

Sci Rep. 2017 Mar 28;7:45287. doi: 10.1038/srep45287.


A team of heterochromatin factors collaborates with small RNA pathways to combat repetitive elements and germline stress.

McMurchy AN, Stempor P, Gaarenstroom T, Wysolmerski B, Dong Y, Aussianikava D, Appert A, Huang N, Kolasinska-Zwierz P, Sapetschnig A, Miska EA, Ahringer J.

Elife. 2017 Mar 15;6. pii: e21666. doi: 10.7554/eLife.21666.


The PRR11-SKA2 Bidirectional Transcription Unit Is Negatively Regulated by p53 through NF-Y in Lung Cancer Cells.

Wang Y, Weng H, Zhang Y, Long Y, Li Y, Niu Y, Song F, Bu Y.

Int J Mol Sci. 2017 Mar 1;18(3). pii: E534. doi: 10.3390/ijms18030534.


Catching moving targets: cancer stem cell hierarchies, therapy-resistance & considerations for clinical intervention.

Gasch C, Ffrench B, O'Leary JJ, Gallagher MF.

Mol Cancer. 2017 Feb 23;16(1):43. doi: 10.1186/s12943-017-0601-3. Review.


Functions of the Tumor Suppressors p53 and Rb in Actin Cytoskeleton Remodeling.

Ebata T, Hirata H, Kawauchi K.

Biomed Res Int. 2016;2016:9231057. doi: 10.1155/2016/9231057. Epub 2016 Dec 18. Review.


The long non-coding RNA GAS5 differentially regulates cell cycle arrest and apoptosis through activation of BRCA1 and p53 in human neuroblastoma.

Mazar J, Rosado A, Shelley J, Marchica J, Westmoreland TJ.

Oncotarget. 2017 Jan 24;8(4):6589-6607. doi: 10.18632/oncotarget.14244.


Downregulation of RNF128 Predicts Progression and Poor Prognosis in Patients with Urothelial Carcinoma of the Upper Tract and Urinary Bladder.

Lee YY, Wang CT, Huang SK, Wu WJ, Huang CN, Li CC, Chan TC, Liang PI, Hsing CH, Li CF.

J Cancer. 2016 Oct 25;7(15):2187-2196. eCollection 2016.


Wip1 inhibitor GSK2830371 inhibits neuroblastoma growth by inducing Chk2/p53-mediated apoptosis.

Chen Z, Wang L, Yao D, Yang T, Cao WM, Dou J, Pang JC, Guan S, Zhang H, Yu Y, Zhao Y, Wang Y, Xu X, Shi Y, Patel R, Zhang H, Vasudevan SA, Liu S, Yang J, Nuchtern JG.

Sci Rep. 2016 Dec 19;6:38011. doi: 10.1038/srep38011.


p53 coordinates DNA repair with nucleotide synthesis by suppressing PFKFB3 expression and promoting the pentose phosphate pathway.

Franklin DA, He Y, Leslie PL, Tikunov AP, Fenger N, Macdonald JM, Zhang Y.

Sci Rep. 2016 Nov 30;6:38067. doi: 10.1038/srep38067.


The Double Role of p53 in Cancer and Autoimmunity and Its Potential as Therapeutic Target.

Fierabracci A, Pellegrino M.

Int J Mol Sci. 2016 Nov 25;17(12). pii: E1975. Review.


Epigenetic inactivation of the p53-induced long noncoding RNA TP53 target 1 in human cancer.

Diaz-Lagares A, Crujeiras AB, Lopez-Serra P, Soler M, Setien F, Goyal A, Sandoval J, Hashimoto Y, Martinez-Cardús A, Gomez A, Heyn H, Moutinho C, Espada J, Vidal A, Paúles M, Galán M, Sala N, Akiyama Y, Martínez-Iniesta M, Farré L, Villanueva A, Gross M, Diederichs S, Guil S, Esteller M.

Proc Natl Acad Sci U S A. 2016 Nov 22;113(47):E7535-E7544. Epub 2016 Nov 7.


p53-/- synergizes with enhanced NrasG12D signaling to transform megakaryocyte-erythroid progenitors in acute myeloid leukemia.

Zhang J, Kong G, Rajagopalan A, Lu L, Song J, Hussaini M, Zhang X, Ranheim EA, Liu Y, Wang J, Gao X, Chang YI, Johnson KD, Zhou Y, Yang D, Bhatnagar B, Lucas DM, Bresnick EH, Zhong X, Padron E, Zhang J.

Blood. 2017 Jan 19;129(3):358-370. doi: 10.1182/blood-2016-06-719237. Epub 2016 Nov 4.


A Novel Role for Pyruvate Kinase M2 as a Corepressor for P53 during the DNA Damage Response in Human Tumor Cells.

Xia L, Wang XR, Wang XL, Liu SH, Ding XW, Chen GQ, Lu Y.

J Biol Chem. 2016 Dec 9;291(50):26138-26150. Epub 2016 Nov 3.


Attractor landscape analysis of colorectal tumorigenesis and its reversion.

Cho SH, Park SM, Lee HS, Lee HY, Cho KH.

BMC Syst Biol. 2016 Oct 20;10(1):96.


Structural Insight into the Critical Role of the N-Terminal Region in the Catalytic Activity of Dual-Specificity Phosphatase 26.

Won EY, Lee SO, Lee DH, Lee D, Bae KH, Lee SC, Kim SJ, Chi SW.

PLoS One. 2016 Sep 1;11(9):e0162115. doi: 10.1371/journal.pone.0162115. eCollection 2016.


Multiple facets of p53 in senescence induction and maintenance.

Johmura Y, Nakanishi M.

Cancer Sci. 2016 Nov;107(11):1550-1555. doi: 10.1111/cas.13060. Epub 2016 Nov 4. Review.

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