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Items: 1 to 20 of 28

1.

Polμ tumor variants decrease the efficiency and accuracy of NHEJ.

Sastre-Moreno G, Pryor JM, Díaz-Talavera A, Ruiz JF, Ramsden DA, Blanco L.

Nucleic Acids Res. 2017 Sep 29;45(17):10018-10031. doi: 10.1093/nar/gkx625.

2.

Close encounters: Moving along bumps, breaks, and bubbles on expanded trinucleotide tracts.

Polyzos AA, McMurray CT.

DNA Repair (Amst). 2017 Aug;56:144-155. doi: 10.1016/j.dnarep.2017.06.017. Epub 2017 Jun 9. Review.

3.

Regulation of human polλ by ATM-mediated phosphorylation during non-homologous end joining.

Sastre-Moreno G, Pryor JM, Moreno-Oñate M, Herrero-Ruiz AM, Cortés-Ledesma F, Blanco L, Ramsden DA, Ruiz JF.

DNA Repair (Amst). 2017 Mar;51:31-45. doi: 10.1016/j.dnarep.2017.01.004. Epub 2017 Jan 17.

4.

Creative template-dependent synthesis by human polymerase mu.

Moon AF, Gosavi RA, Kunkel TA, Pedersen LC, Bebenek K.

Proc Natl Acad Sci U S A. 2015 Aug 18;112(33):E4530-6. doi: 10.1073/pnas.1505798112. Epub 2015 Aug 3.

5.

Essential role for polymerase specialization in cellular nonhomologous end joining.

Pryor JM, Waters CA, Aza A, Asagoshi K, Strom C, Mieczkowski PA, Blanco L, Ramsden DA.

Proc Natl Acad Sci U S A. 2015 Aug 18;112(33):E4537-45. doi: 10.1073/pnas.1505805112. Epub 2015 Aug 3.

6.

Understanding the Physical and Molecular Basis of Stability of Arabidopsis DNA Pol λ under UV-B and High NaCl Stress.

Roy S, Banerjee V, Das KP.

PLoS One. 2015 Jul 31;10(7):e0133843. doi: 10.1371/journal.pone.0133843. eCollection 2015.

7.

N-terminal domains of human DNA polymerase lambda promote primer realignment during translesion DNA synthesis.

Taggart DJ, Dayeh DM, Fredrickson SW, Suo Z.

DNA Repair (Amst). 2014 Oct;22:41-52. doi: 10.1016/j.dnarep.2014.07.008. Epub 2014 Aug 3.

8.

Development of thyroglobulin antibodies after GVAX immunotherapy is associated with prolonged survival.

De Remigis A, de Gruijl TD, Uram JN, Tzou SC, Iwama S, Talor MV, Armstrong TD, Santegoets SJ, Slovin SF, Zheng L, Laheru DA, Jaffee EM, Gerritsen WR, van den Eertwegh AJ, Le DT, Caturegli P.

Int J Cancer. 2015 Jan 1;136(1):127-37. doi: 10.1002/ijc.28973. Epub 2014 May 28.

9.

Structure-function studies of DNA polymerase λ.

Bebenek K, Pedersen LC, Kunkel TA.

Biochemistry. 2014 May 6;53(17):2781-92. doi: 10.1021/bi4017236. Epub 2014 Apr 23. Review.

10.

Structures of the Leishmania infantum polymerase beta.

Mejia E, Burak M, Alonso A, Larraga V, Kunkel TA, Bebenek K, Garcia-Diaz M.

DNA Repair (Amst). 2014 Jun;18:1-9. doi: 10.1016/j.dnarep.2014.03.001. Epub 2014 Mar 22.

11.

Nonhomologous end joining: a good solution for bad ends.

Waters CA, Strande NT, Wyatt DW, Pryor JM, Ramsden DA.

DNA Repair (Amst). 2014 May;17:39-51. doi: 10.1016/j.dnarep.2014.02.008. Epub 2014 Mar 14. Review.

12.

Molecular basis for DNA double-strand break annealing and primer extension by an NHEJ DNA polymerase.

Brissett NC, Martin MJ, Bartlett EJ, Bianchi J, Blanco L, Doherty AJ.

Cell Rep. 2013 Nov 27;5(4):1108-20. doi: 10.1016/j.celrep.2013.10.016. Epub 2013 Nov 14.

13.

Handling the 3-methylcytosine lesion by six human DNA polymerases members of the B-, X- and Y-families.

Furrer A, van Loon B.

Nucleic Acids Res. 2014 Jan;42(1):553-66. doi: 10.1093/nar/gkt889. Epub 2013 Oct 4.

14.

Srs2 prevents Rad51 filament formation by repetitive motion on DNA.

Qiu Y, Antony E, Doganay S, Koh HR, Lohman TM, Myong S.

Nat Commun. 2013;4:2281. doi: 10.1038/ncomms3281.

15.

A specific N-terminal extension of the 8 kDa domain is required for DNA end-bridging by human Polμ and Polλ.

Martin MJ, Garcia-Ortiz MV, Gomez-Bedoya A, Esteban V, Guerra S, Blanco L.

Nucleic Acids Res. 2013 Oct;41(19):9105-16. doi: 10.1093/nar/gkt681. Epub 2013 Aug 8.

16.

Involvement of AtPolλ in the repair of high salt- and DNA cross-linking agent-induced double strand breaks in Arabidopsis.

Roy S, Choudhury SR, Sengupta DN, Das KP.

Plant Physiol. 2013 Jun;162(2):1195-210. doi: 10.1104/pp.113.219022. Epub 2013 May 9.

17.

Human DNA polymerase β, but not λ, can bypass a 2-deoxyribonolactone lesion together with proliferating cell nuclear antigen.

Crespan E, Pasi E, Imoto S, Hübscher U, Greenberg MM, Maga G.

ACS Chem Biol. 2013 Feb 15;8(2):336-44. doi: 10.1021/cb300542k. Epub 2012 Nov 7.

18.

DNA-binding determinants promoting NHEJ by human Polμ.

Martin MJ, Juarez R, Blanco L.

Nucleic Acids Res. 2012 Dec;40(22):11389-403. doi: 10.1093/nar/gks896. Epub 2012 Oct 2.

19.

The human gastric cancer-associated DNA polymerase β variant D160N is a mutator that induces cellular transformation.

Donigan KA, Hile SE, Eckert KA, Sweasy JB.

DNA Repair (Amst). 2012 Apr 1;11(4):381-90. doi: 10.1016/j.dnarep.2012.01.004. Epub 2012 Feb 15.

20.

Metal-induced DNA translocation leads to DNA polymerase conformational activation.

Kirby TW, DeRose EF, Cavanaugh NA, Beard WA, Shock DD, Mueller GA, Wilson SH, London RE.

Nucleic Acids Res. 2012 Apr;40(7):2974-83. doi: 10.1093/nar/gkr1218. Epub 2011 Dec 14.

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