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Items: 1 to 20 of 242

1.

DNA strand breaks and TDP-43 mislocation are absent in the murine hSOD1G93A model of amyotrophic lateral sclerosis in vivo and in vitro.

Penndorf D, Tadić V, Witte OW, Grosskreutz J, Kretz A.

PLoS One. 2017 Aug 23;12(8):e0183684. doi: 10.1371/journal.pone.0183684. eCollection 2017.

2.

Mobilization of LINE-1 retrotransposons is restricted by Tex19.1 in mouse embryonic stem cells.

MacLennan M, García-Cañadas M, Reichmann J, Khazina E, Wagner G, Playfoot CJ, Salvador-Palomeque C, Mann AR, Peressini P, Sanchez L, Dobie K, Read D, Hung CC, Eskeland R, Meehan RR, Weichenrieder O, García-Pérez JL, Adams IR.

Elife. 2017 Aug 14;6. pii: e26152. doi: 10.7554/eLife.26152.

3.

Modeling of TREX1-Dependent Autoimmune Disease using Human Stem Cells Highlights L1 Accumulation as a Source of Neuroinflammation.

Thomas CA, Tejwani L, Trujillo CA, Negraes PD, Herai RH, Mesci P, Macia A, Crow YJ, Muotri AR.

Cell Stem Cell. 2017 Sep 7;21(3):319-331.e8. doi: 10.1016/j.stem.2017.07.009. Epub 2017 Aug 10.

PMID:
28803918
4.

Examining non-LTR retrotransposons in the context of the evolving primate brain.

Linker SB, Marchetto MC, Narvaiza I, Denli AM, Gage FH.

BMC Biol. 2017 Aug 11;15(1):68. doi: 10.1186/s12915-017-0409-z. Review.

5.

Resolving the prevalence of somatic transposition in Drosophila.

Treiber CD, Waddell S.

Elife. 2017 Jul 25;6. pii: e28297. doi: 10.7554/eLife.28297.

6.

Mov10 suppresses retroelements and regulates neuronal development and function in the developing brain.

Skariah G, Seimetz J, Norsworthy M, Lannom MC, Kenny PJ, Elrakhawy M, Forsthoefel C, Drnevich J, Kalsotra A, Ceman S.

BMC Biol. 2017 Jun 29;15(1):54. doi: 10.1186/s12915-017-0387-1.

7.

Transcriptome-wide piRNA profiling in human brains of Alzheimer's disease.

Qiu W, Guo X, Lin X, Yang Q, Zhang W, Zhang Y, Zuo L, Zhu Y, Li CR, Ma C, Luo X.

Neurobiol Aging. 2017 Sep;57:170-177. doi: 10.1016/j.neurobiolaging.2017.05.020. Epub 2017 Jun 3.

PMID:
28654860
8.

The Role of Somatic L1 Retrotransposition in Human Cancers.

Scott EC, Devine SE.

Viruses. 2017 May 31;9(6). pii: E131. doi: 10.3390/v9060131. Review.

9.

Reading LINEs within the cocaine addicted brain.

Doyle GA, Doucet-O'Hare TT, Hammond MJ, Crist RC, Ewing AD, Ferraro TN, Mash DC, Kazazian HH Jr, Berrettini WH.

Brain Behav. 2017 Apr 6;7(5):e00678. doi: 10.1002/brb3.678. eCollection 2017 May.

10.

Dynamic silencing of somatic L1 retrotransposon insertions reflects the developmental and cellular contexts of their genomic integration.

Kannan M, Li J, Fritz SE, Husarek KE, Sanford JC, Sullivan TL, Tiwary PK, An W, Boeke JD, Symer DE.

Mob DNA. 2017 May 10;8:8. doi: 10.1186/s13100-017-0091-2. eCollection 2017.

11.

Heritable L1 retrotransposition in the mouse primordial germline and early embryo.

Richardson SR, Gerdes P, Gerhardt DJ, Sanchez-Luque FJ, Bodea GO, Muñoz-Lopez M, Jesuadian JS, Kempen MHC, Carreira PE, Jeddeloh JA, Garcia-Perez JL, Kazazian HH Jr, Ewing AD, Faulkner GJ.

Genome Res. 2017 Aug;27(8):1395-1405. doi: 10.1101/gr.219022.116. Epub 2017 May 8.

12.

Intersection of diverse neuronal genomes and neuropsychiatric disease: The Brain Somatic Mosaicism Network.

McConnell MJ, Moran JV, Abyzov A, Akbarian S, Bae T, Cortes-Ciriano I, Erwin JA, Fasching L, Flasch DA, Freed D, Ganz J, Jaffe AE, Kwan KY, Kwon M, Lodato MA, Mills RE, Paquola ACM, Rodin RE, Rosenbluh C, Sestan N, Sherman MA, Shin JH, Song S, Straub RE, Thorpe J, Weinberger DR, Urban AE, Zhou B, Gage FH, Lehner T, Senthil G, Walsh CA, Chess A, Courchesne E, Gleeson JG, Kidd JM, Park PJ, Pevsner J, Vaccarino FM; Brain Somatic Mosaicism Network.

Science. 2017 Apr 28;356(6336). pii: eaal1641. doi: 10.1126/science.aal1641. Epub 2017 Apr 27. Review.

13.

Retrotransposon activation contributes to neurodegeneration in a Drosophila TDP-43 model of ALS.

Krug L, Chatterjee N, Borges-Monroy R, Hearn S, Liao WW, Morrill K, Prazak L, Rozhkov N, Theodorou D, Hammell M, Dubnau J.

PLoS Genet. 2017 Mar 16;13(3):e1006635. doi: 10.1371/journal.pgen.1006635. eCollection 2017 Mar.

14.

Effect of aging on stem cells.

Ahmed AS, Sheng MH, Wasnik S, Baylink DJ, Lau KW.

World J Exp Med. 2017 Feb 20;7(1):1-10. doi: 10.5493/wjem.v7.i1.1. eCollection 2017 Feb 20. Review.

15.

Extracellular vesicles as trans-genomic agents: Emerging roles in disease and evolution.

Kawamura Y, Yamamoto Y, Sato TA, Ochiya T.

Cancer Sci. 2017 May;108(5):824-830. doi: 10.1111/cas.13222. Epub 2017 May 18. Review.

16.

Human brain harbors single nucleotide somatic variations in functionally relevant genes possibly mediated by oxidative stress.

Sharma A, Ansari AH, Kumari R, Pandey R, Rehman R, Mehani B, Varma B, Desiraju BK, Mabalirajan U, Agrawal A, Mukhopadhyay A.

Version 3. F1000Res. 2016 Oct 14 [revised 2017 Jan 1];5:2520. doi: 10.12688/f1000research.9495.3. eCollection 2016.

17.

Building a lineage from single cells: genetic techniques for cell lineage tracking.

Woodworth MB, Girskis KM, Walsh CA.

Nat Rev Genet. 2017 Apr;18(4):230-244. doi: 10.1038/nrg.2016.159. Epub 2017 Jan 23. Review.

PMID:
28111472
18.

Engineered LINE-1 retrotransposition in nondividing human neurons.

Macia A, Widmann TJ, Heras SR, Ayllon V, Sanchez L, Benkaddour-Boumzaouad M, Muñoz-Lopez M, Rubio A, Amador-Cubero S, Blanco-Jimenez E, Garcia-Castro J, Menendez P, Ng P, Muotri AR, Goodier JL, Garcia-Perez JL.

Genome Res. 2017 Mar;27(3):335-348. doi: 10.1101/gr.206805.116. Epub 2016 Dec 13.

19.

Inverse changes in L1 retrotransposons between blood and brain in major depressive disorder.

Liu S, Du T, Liu Z, Shen Y, Xiu J, Xu Q.

Sci Rep. 2016 Nov 22;6:37530. doi: 10.1038/srep37530.

20.

TET-dependent regulation of retrotransposable elements in mouse embryonic stem cells.

de la Rica L, Deniz Ö, Cheng KC, Todd CD, Cruz C, Houseley J, Branco MR.

Genome Biol. 2016 Nov 18;17(1):234.

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