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Items: 1 to 20 of 83

1.

STING agonists enable antiviral cross-talk between human cells and confer protection against genital herpes in mice.

Skouboe MK, Knudsen A, Reinert LS, Boularan C, Lioux T, Perouzel E, Thomsen MK, Paludan SR.

PLoS Pathog. 2018 Apr 2;14(4):e1006976. doi: 10.1371/journal.ppat.1006976. eCollection 2018 Apr.

2.

STINGel: Controlled release of a cyclic dinucleotide for enhanced cancer immunotherapy.

Leach DG, Dharmaraj N, Piotrowski SL, Lopez-Silva TL, Lei YL, Sikora AG, Young S, Hartgerink JD.

Biomaterials. 2018 May;163:67-75. doi: 10.1016/j.biomaterials.2018.01.035. Epub 2018 Feb 6.

PMID:
29454236
3.

Signalling strength determines proapoptotic functions of STING.

Gulen MF, Koch U, Haag SM, Schuler F, Apetoh L, Villunger A, Radtke F, Ablasser A.

Nat Commun. 2017 Sep 5;8(1):427. doi: 10.1038/s41467-017-00573-w.

4.

Listening to each other: Infectious disease and cancer immunology.

Vance RE, Eichberg MJ, Portnoy DA, Raulet DH.

Sci Immunol. 2017 Jan 13;2(7). pii: eaai9339. doi: 10.1126/sciimmunol.aai9339. Review.

5.

The Emerging Roles of STING in Bacterial Infections.

Marinho FV, Benmerzoug S, Oliveira SC, Ryffel B, Quesniaux VFJ.

Trends Microbiol. 2017 Nov;25(11):906-918. doi: 10.1016/j.tim.2017.05.008. Epub 2017 Jun 15. Review.

PMID:
28625530
6.

CD103+ Conventional Dendritic Cells Are Critical for TLR7/9-Dependent Host Defense against Histoplasma capsulatum, an Endemic Fungal Pathogen of Humans.

Van Prooyen N, Henderson CA, Hocking Murray D, Sil A.

PLoS Pathog. 2016 Jul 26;12(7):e1005749. doi: 10.1371/journal.ppat.1005749. eCollection 2016 Jul.

7.

Group B Streptococcus Degrades Cyclic-di-AMP to Modulate STING-Dependent Type I Interferon Production.

Andrade WA, Firon A, Schmidt T, Hornung V, Fitzgerald KA, Kurt-Jones EA, Trieu-Cuot P, Golenbock DT, Kaminski PA.

Cell Host Microbe. 2016 Jul 13;20(1):49-59. doi: 10.1016/j.chom.2016.06.003.

8.

The host STING pathway at the interface of cancer and immunity.

Corrales L, McWhirter SM, Dubensky TW Jr, Gajewski TF.

J Clin Invest. 2016 Jul 1;126(7):2404-11. doi: 10.1172/JCI86892. Epub 2016 Jul 1. Review.

9.

Cytosolic Innate Immune Sensing and Signaling upon Infection.

Radoshevich L, Dussurget O.

Front Microbiol. 2016 Mar 14;7:313. doi: 10.3389/fmicb.2016.00313. eCollection 2016. Review.

10.

Vaccine adjuvants as potential cancer immunotherapeutics.

Temizoz B, Kuroda E, Ishii KJ.

Int Immunol. 2016 Jul;28(7):329-38. doi: 10.1093/intimm/dxw015. Epub 2016 Mar 22. Review.

11.

The Vaccine Adjuvant Chitosan Promotes Cellular Immunity via DNA Sensor cGAS-STING-Dependent Induction of Type I Interferons.

Carroll EC, Jin L, Mori A, Muñoz-Wolf N, Oleszycka E, Moran HBT, Mansouri S, McEntee CP, Lambe E, Agger EM, Andersen P, Cunningham C, Hertzog P, Fitzgerald KA, Bowie AG, Lavelle EC.

Immunity. 2016 Mar 15;44(3):597-608. doi: 10.1016/j.immuni.2016.02.004. Epub 2016 Mar 2.

12.

In Vivo Synthesis of Cyclic-di-GMP Using a Recombinant Adenovirus Preferentially Improves Adaptive Immune Responses against Extracellular Antigens.

Alyaqoub FS, Aldhamen YA, Koestler BJ, Bruger EL, Seregin SS, Pereira-Hicks C, Godbehere S, Waters CM, Amalfitano A.

J Immunol. 2016 Feb 15;196(4):1741-52. doi: 10.4049/jimmunol.1501272. Epub 2016 Jan 20.

13.

The emerging roles of the STING adaptor protein in immunity and diseases.

Liu X, Wang C.

Immunology. 2016 Mar;147(3):285-91. doi: 10.1111/imm.12561. Epub 2015 Dec 27. Review.

14.

Molecular Pathways: Targeting the Stimulator of Interferon Genes (STING) in the Immunotherapy of Cancer.

Corrales L, Gajewski TF.

Clin Cancer Res. 2015 Nov 1;21(21):4774-9. doi: 10.1158/1078-0432.CCR-15-1362. Epub 2015 Sep 15. Review.

15.

The emerging role of nuclear viral DNA sensors.

Diner BA, Lum KK, Cristea IM.

J Biol Chem. 2015 Oct 30;290(44):26412-21. doi: 10.1074/jbc.R115.652289. Epub 2015 Sep 9. Review.

16.

Innate Immune Signaling by, and Genetic Adjuvants for DNA Vaccination.

Kobiyama K, Jounai N, Aoshi T, Tozuka M, Takeshita F, Coban C, Ishii KJ.

Vaccines (Basel). 2013 Jul 18;1(3):278-92. doi: 10.3390/vaccines1030278. Review.

17.

Ancient Origin of cGAS-STING Reveals Mechanism of Universal 2',3' cGAMP Signaling.

Kranzusch PJ, Wilson SC, Lee AS, Berger JM, Doudna JA, Vance RE.

Mol Cell. 2015 Sep 17;59(6):891-903. doi: 10.1016/j.molcel.2015.07.022. Epub 2015 Aug 20.

18.

High IFN-γ and low SLPI mark severe asthma in mice and humans.

Raundhal M, Morse C, Khare A, Oriss TB, Milosevic J, Trudeau J, Huff R, Pilewski J, Holguin F, Kolls J, Wenzel S, Ray P, Ray A.

J Clin Invest. 2015 Aug 3;125(8):3037-50. doi: 10.1172/JCI80911. Epub 2015 Jun 29.

19.

STING activator c-di-GMP enhances the anti-tumor effects of peptide vaccines in melanoma-bearing mice.

Wang Z, Celis E.

Cancer Immunol Immunother. 2015 Aug;64(8):1057-66. doi: 10.1007/s00262-015-1713-5. Epub 2015 May 19.

20.

Direct Activation of STING in the Tumor Microenvironment Leads to Potent and Systemic Tumor Regression and Immunity.

Corrales L, Glickman LH, McWhirter SM, Kanne DB, Sivick KE, Katibah GE, Woo SR, Lemmens E, Banda T, Leong JJ, Metchette K, Dubensky TW Jr, Gajewski TF.

Cell Rep. 2015 May 19;11(7):1018-30. doi: 10.1016/j.celrep.2015.04.031. Epub 2015 May 7.

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