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Items: 1 to 20 of 23

1.

Glutamate plasticity woven through the progression to alcohol use disorder: a multi-circuit perspective.

Hwa L, Besheer J, Kash T.

F1000Res. 2017 Mar 21;6:298. doi: 10.12688/f1000research.9609.1. eCollection 2017. Review.

2.

Opposite Effects of mGluR1a and mGluR5 Activation on Nucleus Accumbens Medium Spiny Neuron Dendritic Spine Density.

Gross KS, Brandner DD, Martinez LA, Olive MF, Meisel RL, Mermelstein PG.

PLoS One. 2016 Sep 12;11(9):e0162755. doi: 10.1371/journal.pone.0162755. eCollection 2016.

3.

N-Alkylpyrido[1',2':1,5]pyrazolo-[4,3-d]pyrimidin-4-amines: A new series of negative allosteric modulators of mGlu1/5 with CNS exposure in rodents.

Felts AS, Rodriguez AL, Morrison RD, Venable DF, Blobaum AL, Byers FW, Daniels JS, Niswender CM, Jones CK, Conn PJ, Lindsley CW, Emmitte KA.

Bioorg Med Chem Lett. 2016 Apr 15;26(8):1894-900. doi: 10.1016/j.bmcl.2016.03.026. Epub 2016 Mar 9.

4.

Group 1 mGlu-family proteins promote neuroadaptation to ethanol and withdrawal-associated hippocampal damage.

Reynolds AR, Williams LA, Saunders MA, Prendergast MA.

Drug Alcohol Depend. 2015 Nov 1;156:213-20. doi: 10.1016/j.drugalcdep.2015.09.013. Epub 2015 Sep 26.

5.
6.

The role of varenicline on alcohol-primed self-administration and seeking behavior in rats.

Randall PA, Jaramillo AA, Frisbee S, Besheer J.

Psychopharmacology (Berl). 2015 Jul;232(14):2443-54. doi: 10.1007/s00213-015-3878-1. Epub 2015 Feb 7.

7.

Discovery of VU0431316: a negative allosteric modulator of mGlu5 with activity in a mouse model of anxiety.

Bates BS, Rodriguez AL, Felts AS, Morrison RD, Venable DF, Blobaum AL, Byers FW, Lawson KP, Daniels JS, Niswender CM, Jones CK, Conn PJ, Lindsley CW, Emmitte KA.

Bioorg Med Chem Lett. 2014 Aug 1;24(15):3307-14. doi: 10.1016/j.bmcl.2014.06.003. Epub 2014 Jun 11.

8.

Adrenal steroid hormones and ethanol self-administration in male rhesus macaques.

Helms CM, Park B, Grant KA.

Psychopharmacology (Berl). 2014 Sep;231(17):3425-36. doi: 10.1007/s00213-014-3590-6. Epub 2014 May 1. Erratum in: Psychopharmacology (Berl). 2014 Oct;231(21)::4253. Dosage error in article text.

9.

Stress hormone exposure reduces mGluR5 expression in the nucleus accumbens: functional implications for interoceptive sensitivity to alcohol.

Besheer J, Fisher KR, Jaramillo AA, Frisbee S, Cannady R.

Neuropsychopharmacology. 2014 Sep;39(10):2376-86. doi: 10.1038/npp.2014.85. Epub 2014 Apr 9.

10.

Discovery of VU0409106: A negative allosteric modulator of mGlu5 with activity in a mouse model of anxiety.

Felts AS, Rodriguez AL, Morrison RD, Venable DF, Manka JT, Bates BS, Blobaum AL, Byers FW, Daniels JS, Niswender CM, Jones CK, Conn PJ, Lindsley CW, Emmitte KA.

Bioorg Med Chem Lett. 2013 Nov 1;23(21):5779-85. doi: 10.1016/j.bmcl.2013.09.001. Epub 2013 Sep 10.

11.

Increased extracellular glutamate in the nucleus accumbens promotes excessive ethanol drinking in ethanol dependent mice.

Griffin WC 3rd, Haun HL, Hazelbaker CL, Ramachandra VS, Becker HC.

Neuropsychopharmacology. 2014 Feb;39(3):707-17. doi: 10.1038/npp.2013.256. Epub 2013 Sep 26.

12.

Assessment of the interoceptive effects of alcohol in rats using short-term training procedures.

Besheer J, Fisher KR, Durant B.

Alcohol. 2012 Dec;46(8):747-55. doi: 10.1016/j.alcohol.2012.08.003. Epub 2012 Sep 1.

13.

mGlu receptors and drug addiction.

Cleva RM, Olive MF.

Wiley Interdiscip Rev Membr Transp Signal. 2012 May;1(3):281-295. Epub 2012 Jan 20.

14.

Intra-amygdala inhibition of ERK(1/2) potentiates the discriminative stimulus effects of alcohol.

Besheer J, Fisher KR, Cannady R, Grondin JJ, Hodge CW.

Behav Brain Res. 2012 Mar 17;228(2):398-405. doi: 10.1016/j.bbr.2011.12.023. Epub 2011 Dec 23.

15.

The effects of repeated corticosterone exposure on the interoceptive effects of alcohol in rats.

Besheer J, Fisher KR, Grondin JJ, Cannady R, Hodge CW.

Psychopharmacology (Berl). 2012 Apr;220(4):809-22. doi: 10.1007/s00213-011-2533-8. Epub 2011 Oct 21.

16.
17.

Activation of group II metabotropic glutamate receptors inhibits the discriminative stimulus effects of alcohol via selective activity within the amygdala.

Cannady R, Grondin JJ, Fisher KR, Hodge CW, Besheer J.

Neuropsychopharmacology. 2011 Oct;36(11):2328-38. doi: 10.1038/npp.2011.121. Epub 2011 Jul 6.

18.

Implication of the purinergic system in alcohol use disorders.

Asatryan L, Nam HW, Lee MR, Thakkar MM, Saeed Dar M, Davies DL, Choi DS.

Alcohol Clin Exp Res. 2011 Apr;35(4):584-94. doi: 10.1111/j.1530-0277.2010.01379.x. Epub 2011 Jan 11. Review.

19.

Assessment of GABA-B, metabotropic glutamate, and opioid receptor involvement in an animal model of binge drinking.

Tanchuck MA, Yoneyama N, Ford MM, Fretwell AM, Finn DA.

Alcohol. 2011 Feb;45(1):33-44. doi: 10.1016/j.alcohol.2010.07.009. Epub 2010 Sep 16.

20.

3-Cyano-5-fluoro-N-arylbenzamides as negative allosteric modulators of mGlu(5): Identification of easily prepared tool compounds with CNS exposure in rats.

Felts AS, Lindsley SR, Lamb JP, Rodriguez AL, Menon UN, Jadhav S, Jones CK, Conn PJ, Lindsley CW, Emmitte KA.

Bioorg Med Chem Lett. 2010 Aug 1;20(15):4390-4. doi: 10.1016/j.bmcl.2010.06.064. Epub 2010 Jun 15.

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