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Behavioral Phenotyping and Pathological Indicators of Parkinson's Disease in C. elegans Models.

Maulik M, Mitra S, Bult-Ito A, Taylor BE, Vayndorf EM.

Front Genet. 2017 Jun 13;8:77. doi: 10.3389/fgene.2017.00077. eCollection 2017. Review.


Connecting Ca2+ and lysosomes to Parkinson disease.

Kilpatrick BS.

Messenger (Los Angel). 2016 Jun 1;5(1-2):76-86. doi: 10.1166/msr.2016.1059.


Role of autophagy in the pathogenesis of inflammatory bowel disease.

Iida T, Onodera K, Nakase H.

World J Gastroenterol. 2017 Mar 21;23(11):1944-1953. doi: 10.3748/wjg.v23.i11.1944. Review.


From the baker to the bedside: yeast models of Parkinson's disease.

Menezes R, Tenreiro S, Macedo D, Santos CN, Outeiro TF.

Microb Cell. 2015 Jul 27;2(8):262-279. doi: 10.15698/mic2015.08.219. Review.


Understanding the GTPase Activity of LRRK2: Regulation, Function, and Neurotoxicity.

Nguyen AP, Moore DJ.

Adv Neurobiol. 2017;14:71-88. doi: 10.1007/978-3-319-49969-7_4.


Increased 4R tau expression and behavioural changes in a novel MAPT-N296H genomic mouse model of tauopathy.

Wobst HJ, Denk F, Oliver PL, Livieratos A, Taylor TN, Knudsen MH, Bengoa-Vergniory N, Bannerman D, Wade-Martins R.

Sci Rep. 2017 Feb 24;7:43198. doi: 10.1038/srep43198.


The LRRK2-macroautophagy axis and its relevance to Parkinson's disease.

Manzoni C.

Biochem Soc Trans. 2017 Feb 8;45(1):155-162. doi: 10.1042/BST20160265. Review.


68 and FX2149 Attenuate Mutant LRRK2-R1441C-Induced Neural Transport Impairment.

Thomas JM, Li T, Yang W, Xue F, Fishman PS, Smith WW.

Front Aging Neurosci. 2017 Jan 10;8:337. doi: 10.3389/fnagi.2016.00337. eCollection 2016.


LRRK2 at the interface of autophagosomes, endosomes and lysosomes.

Roosen DA, Cookson MR.

Mol Neurodegener. 2016 Dec 7;11(1):73. doi: 10.1186/s13024-016-0140-1. Review.


PINK1, Parkin, and Mitochondrial Quality Control: What can we Learn about Parkinson's Disease Pathobiology?

Truban D, Hou X, Caulfield TR, Fiesel FC, Springer W.

J Parkinsons Dis. 2017;7(1):13-29. doi: 10.3233/JPD-160989.


LRRK2 contributes to monocyte dysregulation in Parkinson's disease.

Bliederhaeuser C, Zondler L, Grozdanov V, Ruf WP, Brenner D, Melrose HL, Bauer P, Ludolph AC, Gillardon F, Kassubek J, Weishaupt JH, Danzer KM.

Acta Neuropathol Commun. 2016 Nov 24;4(1):123. No abstract available.


Potential protective effects of autophagy activated in MPP+ treated astrocytes.

Shen C, Xian W, Zhou H, Chen L, Pei Z.

Exp Ther Med. 2016 Nov;12(5):2803-2810. Epub 2016 Sep 21.


Activation of FADD-Dependent Neuronal Death Pathways as a Predictor of Pathogenicity for LRRK2 Mutations.

Melachroinou K, Leandrou E, Valkimadi PE, Memou A, Hadjigeorgiou G, Stefanis L, Rideout HJ.

PLoS One. 2016 Nov 10;11(11):e0166053. doi: 10.1371/journal.pone.0166053. eCollection 2016.


mTOR independent regulation of macroautophagy by Leucine Rich Repeat Kinase 2 via Beclin-1.

Manzoni C, Mamais A, Roosen DA, Dihanich S, Soutar MP, Plun-Favreau H, Bandopadhyay R, Hardy J, Tooze SA, Cookson MR, Lewis PA.

Sci Rep. 2016 Oct 12;6:35106. doi: 10.1038/srep35106.


Endolysosomal dysfunction in Parkinson's disease: Recent developments and future challenges.

Kett LR, Dauer WT.

Mov Disord. 2016 Oct;31(10):1433-1443. doi: 10.1002/mds.26797.


LRRK2 modulates microglial activity through regulation of chemokine (C-X3-C) receptor 1 -mediated signalling pathways.

Ma B, Xu L, Pan X, Sun L, Ding J, Xie C, Koliatsos VE, Cai H.

Hum Mol Genet. 2016 Aug 15;25(16):3515-3523. doi: 10.1093/hmg/ddw194. Epub 2016 Jul 4.


Activation Mechanism of LRRK2 and Its Cellular Functions in Parkinson's Disease.

Rosenbusch KE, Kortholt A.

Parkinsons Dis. 2016;2016:7351985. doi: 10.1155/2016/7351985. Epub 2016 May 12. Review.


LRRK2 Regulates Voltage-Gated Calcium Channel Function.

Bedford C, Sears C, Perez-Carrion M, Piccoli G, Condliffe SB.

Front Mol Neurosci. 2016 May 23;9:35. doi: 10.3389/fnmol.2016.00035. eCollection 2016.


TMEM184b Promotes Axon Degeneration and Neuromuscular Junction Maintenance.

Bhattacharya MR, Geisler S, Pittman SK, Doan RA, Weihl CC, Milbrandt J, DiAntonio A.

J Neurosci. 2016 Apr 27;36(17):4681-9. doi: 10.1523/JNEUROSCI.2893-15.2016.


Regulation of LRRK2 promoter activity and gene expression by Sp1.

Wang J, Song W.

Mol Brain. 2016 Mar 22;9:33. doi: 10.1186/s13041-016-0215-5.

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