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Items: 1 to 20 of 122


The Receptor-interacting Serine/Threonine Protein Kinase 1 (RIPK1) Regulates Progranulin Levels.

Mason AR, Elia LP, Finkbeiner S.

J Biol Chem. 2017 Feb 24;292(8):3262-3272. doi: 10.1074/jbc.M116.752006. Epub 2017 Jan 9.


Therapeutic Small Molecules Target Inhibitor of Apoptosis Proteins in Cancers with Deregulation of Extrinsic and Intrinsic Cell Death Pathways.

Derakhshan A, Chen Z, Van Waes C.

Clin Cancer Res. 2017 Mar 15;23(6):1379-1387. doi: 10.1158/1078-0432.CCR-16-2172. Epub 2016 Dec 30. Review.


Cancer's Achilles' Heel: Apoptosis and Necroptosis to the Rescue.

Dasgupta A, Nomura M, Shuck R, Yustein J.

Int J Mol Sci. 2016 Dec 23;18(1). pii: E23. doi: 10.3390/ijms18010023. Review.


Cardiac myofibroblast engulfment of dead cells facilitates recovery after myocardial infarction.

Nakaya M, Watari K, Tajima M, Nakaya T, Matsuda S, Ohara H, Nishihara H, Yamaguchi H, Hashimoto A, Nishida M, Nagasaka A, Horii Y, Ono H, Iribe G, Inoue R, Tsuda M, Inoue K, Tanaka A, Kuroda M, Nagata S, Kurose H.

J Clin Invest. 2017 Jan 3;127(1):383-401. doi: 10.1172/JCI83822. Epub 2016 Dec 5.


Ad-HGF improves the cardiac remodeling of rat following myocardial infarction by upregulating autophagy and necroptosis and inhibiting apoptosis.

Liu J, Wu P, Wang Y, Du Y, A N, Liu S, Zhang Y, Zhou N, Xu Z, Yang Z.

Am J Transl Res. 2016 Nov 15;8(11):4605-4627. eCollection 2016.


Programmed necrosis - a new mechanism of steroidogenic luteal cell death and elimination during luteolysis in cows.

Hojo T, Siemieniuch MJ, Lukasik K, Piotrowska-Tomala KK, Jonczyk AW, Okuda K, Skarzynski DJ.

Sci Rep. 2016 Nov 30;6:38211. doi: 10.1038/srep38211.


Non-benzoquinone geldanamycin analogs trigger various forms of death in human breast cancer cells.

Zhang Z, Li HM, Zhou C, Li Q, Ma L, Zhang Z, Sun Y, Wang L, Zhang X, Zhu B, Hong YS, Wu CZ, Liu H.

J Exp Clin Cancer Res. 2016 Sep 22;35(1):149.


PKC activation sensitizes basal-like breast cancer cell lines to Smac mimetics.

Cornmark L, Holmgren C, Masoumi K, Larsson C.

Cell Death Discov. 2016 Feb 29;2:16002. doi: 10.1038/cddiscovery.2016.2. eCollection 2016.


Post-translational modifications as key regulators of TNF-induced necroptosis.

Liu X, Shi F, Li Y, Yu X, Peng S, Li W, Luo X, Cao Y.

Cell Death Dis. 2016 Jul 7;7(7):e2293. doi: 10.1038/cddis.2016.197. Review.


Tubular epithelial cells in renal clear cell carcinoma express high RIPK1/3 and show increased susceptibility to TNF receptor 1-induced necroptosis.

Al-Lamki RS, Lu W, Manalo P, Wang J, Warren AY, Tolkovsky AM, Pober JS, Bradley JR.

Cell Death Dis. 2016 Jun 30;7(6):e2287. doi: 10.1038/cddis.2016.184.


Silica nanoparticles induce reversible damage of spermatogenic cells via RIPK1 signal pathways in C57 mice.

Ren L, Zhang J, Zou Y, Zhang L, Wei J, Shi Z, Li Y, Guo C, Sun Z, Zhou X.

Int J Nanomedicine. 2016 May 24;11:2251-64. doi: 10.2147/IJN.S102268. eCollection 2016.


SPATA2 links CYLD to the TNF-α receptor signaling complex and modulates the receptor signaling outcomes.

Wagner SA, Satpathy S, Beli P, Choudhary C.

EMBO J. 2016 Sep 1;35(17):1868-84. doi: 10.15252/embj.201694300. Epub 2016 Jun 15.


The Tumor Suppressor Hace1 Is a Critical Regulator of TNFR1-Mediated Cell Fate.

Tortola L, Nitsch R, Bertrand MJ, Kogler M, Redouane Y, Kozieradzki I, Uribesalgo I, Fennell LM, Daugaard M, Klug H, Wirnsberger G, Wimmer R, Perlot T, Sarao R, Rao S, Hanada T, Takahashi N, Kernbauer E, Demiröz D, Superti-Furga G, Decker T, Pichler A, Ikeda F, Kroemer G, Vandenabeele P, Sorensen PH, Penninger JM.

Cell Rep. 2016 May 17;15(7):1481-92. doi: 10.1016/j.celrep.2016.04.032. Epub 2016 May 5.


Distinct cytoprotective roles of pyruvate and ATP by glucose metabolism on epithelial necroptosis and crypt proliferation in ischaemic gut.

Huang CY, Kuo WT, Huang CY, Lee TC, Chen CT, Peng WH, Lu KS, Yang CY, Yu LC.

J Physiol. 2017 Jan 15;595(2):505-521. doi: 10.1113/JP272208. Epub 2016 Jun 17.


Heat shock protein 90 regulates necroptosis by modulating multiple signaling effectors.

Yang CK, He SD.

Cell Death Dis. 2016 Mar 3;7:e2126. doi: 10.1038/cddis.2016.25. No abstract available.


Cyclophilin D regulates necrosis, but not apoptosis, of murine eosinophils.

Zhu X, Hogan SP, Molkentin JD, Zimmermann N.

Am J Physiol Gastrointest Liver Physiol. 2016 Apr 15;310(8):G609-17. doi: 10.1152/ajpgi.00389.2015. Epub 2016 Feb 18.


Role of necroptosis in the pathogenesis of solid organ injury.

Zhao H, Jaffer T, Eguchi S, Wang Z, Linkermann A, Ma D.

Cell Death Dis. 2015 Nov 19;6:e1975. doi: 10.1038/cddis.2015.316. Review.


Herpes Simplex Virus 1 (HSV-1) and HSV-2 Mediate Species-Specific Modulations of Programmed Necrosis through the Viral Ribonucleotide Reductase Large Subunit R1.

Yu X, Li Y, Chen Q, Su C, Zhang Z, Yang C, Hu Z, Hou J, Zhou J, Gong L, Jiang X, Zheng C, He S.

J Virol. 2015 Nov 11;90(2):1088-95. doi: 10.1128/JVI.02446-15.


Pathophysiological mechanisms of death resistance in colorectal carcinoma.

Huang CY, Yu LC.

World J Gastroenterol. 2015 Nov 7;21(41):11777-92. doi: 10.3748/wjg.v21.i41.11777. Review.

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