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Items: 1 to 20 of 46


Enantioselective allylic alkylation of stereodefined polysubstituted copper enolates as an entry to acyclic quaternary carbon stereocentres.

Nairoukh Z, Kumar GGKSN, Minko Y, Marek I.

Chem Sci. 2017 Jan 1;8(1):627-630. doi: 10.1039/c6sc03036j. Epub 2016 Sep 15.


Divergent synthesis and identification of the cellular targets of deoxyelephantopins.

Lagoutte R, Serba C, Abegg D, Hoch DG, Adibekian A, Winssinger N.

Nat Commun. 2016 Aug 19;7:12470. doi: 10.1038/ncomms12470.


Marine Invertebrate Metabolites with Anticancer Activities: Solutions to the "Supply Problem".

Gomes NG, Dasari R, Chandra S, Kiss R, Kornienko A.

Mar Drugs. 2016 May 21;14(5). pii: E98. doi: 10.3390/md14050098. Review.


New Insights into the Biosynthetic Logic of Ribosomally Synthesized and Post-translationally Modified Peptide Natural Products.

Ortega MA, van der Donk WA.

Cell Chem Biol. 2016 Jan 21;23(1):31-44. doi: 10.1016/j.chembiol.2015.11.012. Review.


Rhodium-Catalyzed Stereoselective Intramolecular [5 + 2] Cycloaddition of 3-Acyloxy 1,4-Enyne and Alkene.

Shu XZ, Schienebeck CM, Li X, Zhou X, Song W, Chen L, Guzei IA, Tang W.

Org Lett. 2015 Oct 16;17(20):5128-31. doi: 10.1021/acs.orglett.5b02665. Epub 2015 Oct 6.


A concise synthesis of (+)-batzelladine B from simple pyrrole-based starting materials.

Parr BT, Economou C, Herzon SB.

Nature. 2015 Sep 24;525(7570):507-10. doi: 10.1038/nature14902. Epub 2015 Sep 16.


Tetramethyleneethane Equivalents: Recursive Reagents for Serialized Cycloadditions.

Wender PA, Jeffreys MS, Raub AG.

J Am Chem Soc. 2015 Jul 22;137(28):9088-93. doi: 10.1021/jacs.5b04091. Epub 2015 May 29.


Function through synthesis-informed design.

Wender PA, Quiroz RV, Stevens MC.

Acc Chem Res. 2015 Mar 17;48(3):752-60. doi: 10.1021/acs.accounts.5b00004. Epub 2015 Mar 5.


Spirotetronate polyketides as leads in drug discovery.

Lacoske MH, Theodorakis EA.

J Nat Prod. 2015 Mar 27;78(3):562-75. doi: 10.1021/np500757w. Epub 2014 Dec 1. Review.


Synthesis of partially O-acetylated N-acetylneuraminic acid using regioselective silyl exchange technology.

Park SS, Gervay-Hague J.

Org Lett. 2014 Oct 3;16(19):5044-7. doi: 10.1021/ol502389g. Epub 2014 Sep 23.


Improved protein kinase C affinity through final step diversification of a simplified salicylate-derived bryostatin analog scaffold.

Wender PA, Staveness D.

Org Lett. 2014 Oct 3;16(19):5140-3. doi: 10.1021/ol502492b. Epub 2014 Sep 19.


Computer-guided design, synthesis, and protein kinase C affinity of a new salicylate-based class of bryostatin analogs.

Wender PA, Nakagawa Y, Near KE, Staveness D.

Org Lett. 2014 Oct 3;16(19):5136-9. doi: 10.1021/ol502491f. Epub 2014 Sep 19.


Nickel-catalyzed intramolecular [3 + 2 + 2] cycloadditions of alkylidenecyclopropanes. A straightforward entry to fused 6,7,5-tricyclic systems.

Saya L, Fernández I, López F, Mascareñas JL.

Org Lett. 2014 Oct 3;16(19):5008-11. doi: 10.1021/ol502288x. Epub 2014 Sep 18.


Molecular systems pharmacology: isoelectric focusing signature of protein kinase Cδ provides an integrated measure of its modulation in response to ligands.

Kedei N, Chen JQ, Herrmann MA, Telek A, Goldsmith PK, Petersen ME, Keck GE, Blumberg PM.

J Med Chem. 2014 Jun 26;57(12):5356-69. doi: 10.1021/jm500417b. Epub 2014 Jun 6.

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