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The third group of the B7-CD28 immune checkpoint family: HHLA2, TMIGD2, B7x, and B7-H3.

Janakiram M, Shah UA, Liu W, Zhao A, Schoenberg MP, Zang X.

Immunol Rev. 2017 Mar;276(1):26-39. doi: 10.1111/imr.12521. Review.


From cell biology to immunology: Controlling metastatic progression of cancer via microRNA regulatory networks.

Park JH, Theodoratou E, Calin GA, Shin JI.

Oncoimmunology. 2016 Sep 9;5(11):e1230579. doi: 10.1080/2162402X.2016.1230579. Review.


TGF-β1 promotes colorectal cancer immune escape by elevating B7-H3 and B7-H4 via the miR-155/miR-143 axis.

Zhou X, Mao Y, Zhu J, Meng F, Chen Q, Tao L, Li R, Fu F, Liu C, Hu Y, Wang W, Zhang H, Hua D, Chen W, Zhang X.

Oncotarget. 2016 Oct 11;7(41):67196-67211. doi: 10.18632/oncotarget.11950.


MicroRNA-491 regulates the proliferation and apoptosis of CD8(+) T cells.

Yu T, Zuo QF, Gong L, Wang LN, Zou QM, Xiao B.

Sci Rep. 2016 Aug 3;6:30923. doi: 10.1038/srep30923.


miR-29c contribute to glioma cells temozolomide sensitivity by targeting O6-methylguanine-DNA methyltransferases indirectely.

Xiao S, Yang Z, Qiu X, Lv R, Liu J, Wu M, Liao Y, Liu Q.

Oncotarget. 2016 Aug 2;7(31):50229-50238. doi: 10.18632/oncotarget.10357.


Targeting microRNAs as key modulators of tumor immune response.

Paladini L, Fabris L, Bottai G, Raschioni C, Calin GA, Santarpia L.

J Exp Clin Cancer Res. 2016 Jun 27;35:103. doi: 10.1186/s13046-016-0375-2. Review.


MicroRNA-187 inhibits tumor growth and invasion by directly targeting CD276 in colorectal cancer.

Wang ZS, Zhong M, Bian YH, Mu YF, Qin SL, Yu MH, Qin J.

Oncotarget. 2016 Jul 12;7(28):44266-44276. doi: 10.18632/oncotarget.10023.


Essential role of miRNAs in orchestrating the biology of the tumor microenvironment.

Frediani JN, Fabbri M.

Mol Cancer. 2016 May 26;15(1):42. doi: 10.1186/s12943-016-0525-3. Review.


Molecular Pathways: Targeting B7-H3 (CD276) for Human Cancer Immunotherapy.

Picarda E, Ohaegbulam KC, Zang X.

Clin Cancer Res. 2016 Jul 15;22(14):3425-31. doi: 10.1158/1078-0432.CCR-15-2428.


Coinhibitory Pathways in the B7-CD28 Ligand-Receptor Family.

Schildberg FA, Klein SR, Freeman GJ, Sharpe AH.

Immunity. 2016 May 17;44(5):955-72. doi: 10.1016/j.immuni.2016.05.002. Review.


B7-H3 as a promising target for cytotoxicity T cell in human cancer therapy.

Ma J, Ma P, Zhao C, Xue X, Han H, Liu C, Tao H, Xiu W, Cai J, Zhang M.

Oncotarget. 2016 May 17;7(20):29480-91. doi: 10.18632/oncotarget.8784.


Development of DS-5573a: A novel afucosylated mAb directed at B7-H3 with potent antitumor activity.

Nagase-Zembutsu A, Hirotani K, Yamato M, Yamaguchi J, Takata T, Yoshida M, Fukuchi K, Yazawa M, Takahashi S, Agatsuma T.

Cancer Sci. 2016 May;107(5):674-81. doi: 10.1111/cas.12915.


Humanized Affinity-matured Monoclonal Antibody 8H9 Has Potent Antitumor Activity and Binds to FG Loop of Tumor Antigen B7-H3.

Ahmed M, Cheng M, Zhao Q, Goldgur Y, Cheal SM, Guo HF, Larson SM, Cheung NK.

J Biol Chem. 2015 Dec 11;290(50):30018-29. doi: 10.1074/jbc.M115.679852.


Small molecules targeting microRNA for cancer therapy: Promises and obstacles.

Wen D, Danquah M, Chaudhary AK, Mahato RI.

J Control Release. 2015 Dec 10;219:237-47. doi: 10.1016/j.jconrel.2015.08.011. Review.


B7-H3 silencing by RNAi inhibits tumor progression and enhances chemosensitivity in U937 cells.

Zhang W, Wang J, Wang Y, Dong F, Zhu M, Wan W, Li H, Wu F, Yan X, Ke X.

Onco Targets Ther. 2015 Jul 14;8:1721-33. doi: 10.2147/OTT.S85272.


Radioimmunotherapy of human tumours.

Larson SM, Carrasquillo JA, Cheung NK, Press OW.

Nat Rev Cancer. 2015 Jun;15(6):347-60. doi: 10.1038/nrc3925. Review. Erratum in: Nat Rev Cancer. 2015 Aug;15(8):509.


Reduced miR-29a-3p expression is linked to the cell proliferation and cell migration in gastric cancer.

Zhao Z, Wang L, Song W, Cui H, Chen G, Qiao F, Hu J, Zhou R, Fan H.

World J Surg Oncol. 2015 Mar 12;13:101. doi: 10.1186/s12957-015-0513-x.


The role of miR-29b in cancer: regulation, function, and signaling.

Yan B, Guo Q, Fu FJ, Wang Z, Yin Z, Wei YB, Yang JR.

Onco Targets Ther. 2015 Mar 3;8:539-48. doi: 10.2147/OTT.S75899. Review.


MicroRNA modulators of epigenetic regulation, the tumor microenvironment and the immune system in lung cancer.

Rusek AM, Abba M, Eljaszewicz A, Moniuszko M, Niklinski J, Allgayer H.

Mol Cancer. 2015 Feb 7;14:34. doi: 10.1186/s12943-015-0302-8. Review.


The CD28-B7 Family in Anti-Tumor Immunity: Emerging Concepts in Cancer Immunotherapy.

Leung J, Suh WK.

Immune Netw. 2014 Dec;14(6):265-76. doi: 10.4110/in.2014.14.6.265. Review.

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