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Gulonolactone Addition to Human Hepatocellular Carcinoma Cells with Gene Transfer of Gulonolactone Oxidase Restores Ascorbate Biosynthesis and Reduces Hypoxia Inducible Factor 1.

Flett T, Campbell EJ, Phillips E, Vissers MCM, Dachs GU.

Biomedicines. 2014 Mar 5;2(1):98-109. doi: 10.3390/biomedicines2010098.


Chemopreventive Agents and Inhibitors of Cancer Hallmarks: May Citrus Offer New Perspectives?

Cirmi S, Ferlazzo N, Lombardo GE, Maugeri A, Calapai G, Gangemi S, Navarra M.

Nutrients. 2016 Nov 4;8(11). pii: E698. Review.


Effects of histidine and vitamin C on isoproterenol-induced acute myocardial infarction in rats.

Moradi-Arzeloo M, Farshid AA, Tamaddonfard E, Asri-Rezaei S.

Vet Res Forum. 2016 Winter;7(1):47-54. Epub 2016 Mar 15.


The epigenetic role of vitamin C in health and disease.

Camarena V, Wang G.

Cell Mol Life Sci. 2016 Apr;73(8):1645-58. doi: 10.1007/s00018-016-2145-x. Epub 2016 Feb 4. Review.


Qualitative and quantitative proteomic analysis of Vitamin C induced changes in Mycobacterium smegmatis.

Mishra A, Sarkar D.

Front Microbiol. 2015 May 18;6:451. doi: 10.3389/fmicb.2015.00451. eCollection 2015.


mtDNA Mutagenesis Disrupts Pluripotent Stem Cell Function by Altering Redox Signaling.

Hämäläinen RH, Ahlqvist KJ, Ellonen P, Lepistö M, Logan A, Otonkoski T, Murphy MP, Suomalainen A.

Cell Rep. 2015 Jun 16;11(10):1614-24. doi: 10.1016/j.celrep.2015.05.009. Epub 2015 May 28.


Regulation of the Epigenome by Vitamin C.

Young JI, Züchner S, Wang G.

Annu Rev Nutr. 2015;35:545-64. doi: 10.1146/annurev-nutr-071714-034228. Epub 2015 May 6. Review.


A cross-kingdom history.

Fernie AR, Tohge T.

Elife. 2015 Apr 15;4. doi: 10.7554/eLife.07527. No abstract available.


Blood markers of oxidative stress predict weaning failure from mechanical ventilation.

Verona C, Hackenhaar FS, Teixeira C, Medeiros TM, Alabarse PV, Salomon TB, Shüller ÁK, Maccari JG, Condessa RL, Oliveira RP, Rios Vieira SR, Benfato MS.

J Cell Mol Med. 2015 Jun;19(6):1253-61. doi: 10.1111/jcmm.12475. Epub 2015 Apr 9.


Skin changes after bariatric surgery.

Manzoni AP, Weber MB.

An Bras Dermatol. 2015 Mar-Apr;90(2):157-66. doi: 10.1590/abd1806-4841.20153139.


Evolution of alternative biosynthetic pathways for vitamin C following plastid acquisition in photosynthetic eukaryotes.

Wheeler G, Ishikawa T, Pornsaksit V, Smirnoff N.

Elife. 2015 Mar 13;4. doi: 10.7554/eLife.06369.


An upstream open reading frame is essential for feedback regulation of ascorbate biosynthesis in Arabidopsis.

Laing WA, Martínez-Sánchez M, Wright MA, Bulley SM, Brewster D, Dare AP, Rassam M, Wang D, Storey R, Macknight RC, Hellens RP.

Plant Cell. 2015 Mar;27(3):772-86. doi: 10.1105/tpc.114.133777. Epub 2015 Feb 27.


Gingival overgrowth caused by vitamin C deficiency associated with metabolic syndrome and severe periodontal infection: a case report.

Omori K, Hanayama Y, Naruishi K, Akiyama K, Maeda H, Otsuka F, Takashiba S.

Clin Case Rep. 2014 Dec;2(6):286-95. doi: 10.1002/ccr3.114. Epub 2014 Sep 4.


Vitamins and type 2 diabetes mellitus.

Valdés-Ramos R, Guadarrama-López AL, Martínez-Carrillo BE, Benítez-Arciniega AD.

Endocr Metab Immune Disord Drug Targets. 2015;15(1):54-63. Review.


Restoring physiological levels of ascorbate slows tumor growth and moderates HIF-1 pathway activity in Gulo(-/-) mice.

Campbell EJ, Vissers MC, Bozonet S, Dyer A, Robinson BA, Dachs GU.

Cancer Med. 2015 Feb;4(2):303-14. doi: 10.1002/cam4.349. Epub 2014 Oct 30.


Effect of high dose vitamin C on Epstein-Barr viral infection.

Mikirova N, Hunninghake R.

Med Sci Monit. 2014 May 3;20:725-32. doi: 10.12659/MSM.890423.


Genetic polymorphisms in SLC23A2 as predictive biomarkers of severe acute toxicities after treatment with a definitive 5-fluorouracil/cisplatin-based chemoradiotherapy in Japanese patients with esophageal squamous cell carcinoma.

Minegaki T, Kuwahara A, Yamamori M, Nakamura T, Okuno T, Miki I, Omatsu H, Tamura T, Hirai M, Azuma T, Sakaeda T, Nishiguchi K.

Int J Med Sci. 2014 Feb 7;11(4):321-6. doi: 10.7150/ijms.7654. eCollection 2014.


The human sodium-dependent ascorbic acid transporters SLC23A1 and SLC23A2 do not mediate ascorbic acid release in the proximal renal epithelial cell.

Eck P, Kwon O, Chen S, Mian O, Levine M.

Physiol Rep. 2013 Nov;1(6):e00136. doi: 10.1002/phy2.136. Epub 2013 Nov 7.


Selective killing effect of oxytetracycline, propafenone and metamizole on A549 or Hela cells.

Shao J, Feng G.

Chin J Cancer Res. 2013 Dec;25(6):662-70. doi: 10.3978/j.issn.1000-9604.2013.11.05.


Ascorbic Acid Biosynthesis and Brackish Water Acclimation in the Euryhaline Freshwater White-Rimmed Stingray, Himantura signifer.

Wong SZ, Ching B, Chng YR, Wong WP, Chew SF, Ip YK.

PLoS One. 2013 Jun 18;8(6):e66691. doi: 10.1371/journal.pone.0066691. Print 2013.

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