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Items: 20


Quantitative analysis of human centrosome architecture by targeted proteomics and fluorescence imaging.

Bauer M, Cubizolles F, Schmidt A, Nigg EA.

EMBO J. 2016 Oct 4;35(19):2152-2166. Epub 2016 Aug 18.


Promotion and Suppression of Centriole Duplication Are Catalytically Coupled through PLK4 to Ensure Centriole Homeostasis.

Kim M, O'Rourke BP, Soni RK, Jallepalli PV, Hendrickson RC, Tsou MB.

Cell Rep. 2016 Aug 2;16(5):1195-1203. doi: 10.1016/j.celrep.2016.06.069. Epub 2016 Jul 14.


The Spindle Assembly Checkpoint Is Not Essential for Viability of Human Cells with Genetically Lowered APC/C Activity.

Wild T, Larsen MS, Narita T, Schou J, Nilsson J, Choudhary C.

Cell Rep. 2016 Mar 1;14(8):1829-40. doi: 10.1016/j.celrep.2016.01.060. Epub 2016 Feb 18.


Probing the catalytic functions of Bub1 kinase using the small molecule inhibitors BAY-320 and BAY-524.

Baron AP, von Schubert C, Cubizolles F, Siemeister G, Hitchcock M, Mengel A, Schröder J, Fernández-Montalván A, von Nussbaum F, Mumberg D, Nigg EA.

Elife. 2016 Feb 17;5. pii: e12187. doi: 10.7554/eLife.12187.


Cohesin recruits the Esco1 acetyltransferase genome wide to repress transcription and promote cohesion in somatic cells.

Rahman S, Jones MJ, Jallepalli PV.

Proc Natl Acad Sci U S A. 2015 Sep 8;112(36):11270-5. doi: 10.1073/pnas.1505323112. Epub 2015 Aug 24.


p53 protects against genome instability following centriole duplication failure.

Lambrus BG, Uetake Y, Clutario KM, Daggubati V, Snyder M, Sluder G, Holland AJ.

J Cell Biol. 2015 Jul 6;210(1):63-77. doi: 10.1083/jcb.201502089.


Efficient CRISPR-rAAV engineering of endogenous genes to study protein function by allele-specific RNAi.

Kaulich M, Lee YJ, Lönn P, Springer AD, Meade BR, Dowdy SF.

Nucleic Acids Res. 2015 Apr 20;43(7):e45. doi: 10.1093/nar/gku1403. Epub 2015 Jan 13.


The quantitative architecture of centromeric chromatin.

Bodor DL, Mata JF, Sergeev M, David AF, Salimian KJ, Panchenko T, Cleveland DW, Black BE, Shah JV, Jansen LE.

Elife. 2014 Jul 15;3:e02137. doi: 10.7554/eLife.02137.


Nuclear pores protect genome integrity by assembling a premitotic and Mad1-dependent anaphase inhibitor.

Rodriguez-Bravo V, Maciejowski J, Corona J, Buch HK, Collin P, Kanemaki MT, Shah JV, Jallepalli PV.

Cell. 2014 Feb 27;156(5):1017-31. doi: 10.1016/j.cell.2014.01.010.


A role for XLF in DNA repair and recombination in human somatic cells.

Fattah FJ, Kweon J, Wang Y, Lee EH, Kan Y, Lichter N, Weisensel N, Hendrickson EA.

DNA Repair (Amst). 2014 Mar;15:39-53. doi: 10.1016/j.dnarep.2013.12.006. Epub 2014 Jan 21.


A two-step mechanism for epigenetic specification of centromere identity and function.

Fachinetti D, Folco HD, Nechemia-Arbely Y, Valente LP, Nguyen K, Wong AJ, Zhu Q, Holland AJ, Desai A, Jansen LE, Cleveland DW.

Nat Cell Biol. 2013 Sep;15(9):1056-66. doi: 10.1038/ncb2805. Epub 2013 Jul 21.


A stringent requirement for Plk1 T210 phosphorylation during K-fiber assembly and chromosome congression.

Paschal CR, Maciejowski J, Jallepalli PV.

Chromosoma. 2012 Dec;121(6):565-72. doi: 10.1007/s00412-012-0375-8. Epub 2012 May 9.


Polo-like kinase 4 controls centriole duplication but does not directly regulate cytokinesis.

Holland AJ, Fachinetti D, Da Cruz S, Zhu Q, Vitre B, Lince-Faria M, Chen D, Parish N, Verma IM, Bettencourt-Dias M, Cleveland DW.

Mol Biol Cell. 2012 May;23(10):1838-45. doi: 10.1091/mbc.E11-12-1043. Epub 2012 Mar 28.


A rapid FACS-based strategy to isolate human gene knockin and knockout clones.

Mata JF, Lopes T, Gardner R, Jansen LE.

PLoS One. 2012;7(2):e32646. doi: 10.1371/journal.pone.0032646. Epub 2012 Feb 29.


APC15 drives the turnover of MCC-CDC20 to make the spindle assembly checkpoint responsive to kinetochore attachment.

Mansfeld J, Collin P, Collins MO, Choudhary JS, Pines J.

Nat Cell Biol. 2011 Sep 18;13(10):1234-43. doi: 10.1038/ncb2347.


Springs, clutches and motors: driving forward kinetochore mechanism by modelling.

Vladimirou E, Harry E, Burroughs N, McAinsh AD.

Chromosome Res. 2011 Apr;19(3):409-21. doi: 10.1007/s10577-011-9191-x. Review.


Vigilance and validation: Keys to success in RNAi screening.

Sigoillot FD, King RW.

ACS Chem Biol. 2011 Jan 21;6(1):47-60. doi: 10.1021/cb100358f. Epub 2010 Dec 28. Review.


Mps1 directs the assembly of Cdc20 inhibitory complexes during interphase and mitosis to control M phase timing and spindle checkpoint signaling.

Maciejowski J, George KA, Terret ME, Zhang C, Shokat KM, Jallepalli PV.

J Cell Biol. 2010 Jul 12;190(1):89-100. doi: 10.1083/jcb.201001050.


Vertebrate cells genetically deficient for Cdc14A or Cdc14B retain DNA damage checkpoint proficiency but are impaired in DNA repair.

Mocciaro A, Berdougo E, Zeng K, Black E, Vagnarelli P, Earnshaw W, Gillespie D, Jallepalli P, Schiebel E.

J Cell Biol. 2010 May 17;189(4):631-9. doi: 10.1083/jcb.200910057.


Ku regulates the non-homologous end joining pathway choice of DNA double-strand break repair in human somatic cells.

Fattah F, Lee EH, Weisensel N, Wang Y, Lichter N, Hendrickson EA.

PLoS Genet. 2010 Feb 26;6(2):e1000855. doi: 10.1371/journal.pgen.1000855.

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