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Items: 1 to 20 of 177


Single-cell analysis of HIV-1 transcriptional activity reveals expression of proviruses in expanded clones during ART.

Wiegand A, Spindler J, Hong FF, Shao W, Cyktor JC, Cillo AR, Halvas EK, Coffin JM, Mellors JW, Kearney MF.

Proc Natl Acad Sci U S A. 2017 May 2;114(18):E3659-E3668. doi: 10.1073/pnas.1617961114. Epub 2017 Apr 17.


HIV Persistence in Gut-Associated Lymphoid Tissues: Pharmacological Challenges and Opportunities.

Thompson CG, Gay CL, Kashuba ADM.

AIDS Res Hum Retroviruses. 2017 Jun;33(6):513-523. doi: 10.1089/AID.2016.0253. Epub 2017 May 16.


Proviruses with identical sequences comprise a large fraction of the replication-competent HIV reservoir.

Bui JK, Sobolewski MD, Keele BF, Spindler J, Musick A, Wiegand A, Luke BT, Shao W, Hughes SH, Coffin JM, Kearney MF, Mellors JW.

PLoS Pathog. 2017 Mar 22;13(3):e1006283. doi: 10.1371/journal.ppat.1006283. eCollection 2017 Mar.


Different Pathways Leading to Integrase Inhibitors Resistance.

Thierry E, Deprez E, Delelis O.

Front Microbiol. 2017 Jan 11;7:2165. doi: 10.3389/fmicb.2016.02165. eCollection 2016. Review.


Achieving HIV-1 Control through RNA-Directed Gene Regulation.

Klemm V, Mitchell J, Cortez-Jugo C, Cavalieri F, Symonds G, Caruso F, Kelleher AD, Ahlenstiel C.

Genes (Basel). 2016 Dec 7;7(12). pii: E119. Review.


Limited HIV-1 Reactivation in Resting CD4+ T cells from Aviremic Patients under Protease Inhibitors.

Kumar A, Abbas W, Bouchat S, Gatot JS, Pasquereau S, Kabeya K, Clumeck N, De Wit S, Van Lint C, Herbein G.

Sci Rep. 2016 Dec 6;6:38313. doi: 10.1038/srep38313.


Paired quantitative and qualitative assessment of the replication-competent HIV-1 reservoir and comparison with integrated proviral DNA.

Lorenzi JC, Cohen YZ, Cohn LB, Kreider EF, Barton JP, Learn GH, Oliveira T, Lavine CL, Horwitz JA, Settler A, Jankovic M, Seaman MS, Chakraborty AK, Hahn BH, Caskey M, Nussenzweig MC.

Proc Natl Acad Sci U S A. 2016 Dec 6;113(49):E7908-E7916. Epub 2016 Nov 21. Erratum in: Proc Natl Acad Sci U S A. 2017 Jan 17;:.


Prolonged persistence of a novel replication-defective HIV-1 variant in plasma of a patient on suppressive therapy.

Rassler S, Ramirez R, Khoury N, Skowron G, Sahu GK.

Virol J. 2016 Sep 21;13(1):157.


Multi-dose Romidepsin Reactivates Replication Competent SIV in Post-antiretroviral Rhesus Macaque Controllers.

Policicchio BB, Xu C, Brocca-Cofano E, Raehtz KD, He T, Ma D, Li H, Sivanandham R, Haret-Richter GS, Dunsmore T, Trichel A, Mellors JW, Hahn BH, Shaw GM, Ribeiro RM, Pandrea I, Apetrei C.

PLoS Pathog. 2016 Sep 15;12(9):e1005879. doi: 10.1371/journal.ppat.1005879. eCollection 2016 Sep.


Lack of concordance between residual viremia and viral variants driving de novo infection of CD4(+) T cells on ART.

Puertas MC, Noguera-Julian M, Massanella M, Pou C, Buzon MJ, Clotet B, Stevenson M, Paredes R, Blanco J, Martinez-Picado J.

Retrovirology. 2016 Aug 2;13(1):51. doi: 10.1186/s12977-016-0282-9.


Immunological and pharmacological strategies to reactivate HIV-1 from latently infected cells: a possibility for HIV-1 paediatric patients?

Martínez-Bonet M, Clemente MI, Serramía MJ, Moreno S, Muñoz E, Muñoz-Fernández MA.

J Virus Erad. 2015 Jul 1;1(3):148-52. Review.


Latency reversal and viral clearance to cure HIV-1.

Margolis DM, Garcia JV, Hazuda DJ, Haynes BF.

Science. 2016 Jul 22;353(6297):aaf6517. doi: 10.1126/science.aaf6517. Review.


The Latent Reservoir for HIV-1: How Immunologic Memory and Clonal Expansion Contribute to HIV-1 Persistence.

Murray AJ, Kwon KJ, Farber DL, Siliciano RF.

J Immunol. 2016 Jul 15;197(2):407-17. doi: 10.4049/jimmunol.1600343. Review.


What Integration Sites Tell Us about HIV Persistence.

Hughes SH, Coffin JM.

Cell Host Microbe. 2016 May 11;19(5):588-98. doi: 10.1016/j.chom.2016.04.010. Review.


What happens to cardiovascular system behind the undetectable level of HIV viremia?

d'Ettorre G, Ceccarelli G, Pavone P, Vittozzi P, De Girolamo G, Schietroma I, Serafino S, Giustini N, Vullo V.

AIDS Res Ther. 2016 Apr 27;13:21. doi: 10.1186/s12981-016-0105-z. eCollection 2016. Review.


Real-Time Predictions of Reservoir Size and Rebound Time during Antiretroviral Therapy Interruption Trials for HIV.

Hill AL, Rosenbloom DI, Goldstein E, Hanhauser E, Kuritzkes DR, Siliciano RF, Henrich TJ.

PLoS Pathog. 2016 Apr 27;12(4):e1005535. doi: 10.1371/journal.ppat.1005535. eCollection 2016 Apr. Erratum in: PLoS Pathog. 2016 Jul;12(7):e1005778. PLoS Pathog. 2017 Jul 6;13(7):e1006488.


Persistent HIV-1 replication during antiretroviral therapy.

Martinez-Picado J, Deeks SG.

Curr Opin HIV AIDS. 2016 Jul;11(4):417-23. doi: 10.1097/COH.0000000000000287.


Inflammation, immune activation, and cardiovascular disease in HIV.

Nou E, Lo J, Grinspoon SK.

AIDS. 2016 Jun 19;30(10):1495-509. doi: 10.1097/QAD.0000000000001109.


Barriers to a cure for HIV in women.

Gianella S, Tsibris A, Barr L, Godfrey C.

J Int AIDS Soc. 2016 Feb 18;19(1):20706. doi: 10.7448/IAS.19.1.20706. eCollection 2016. Review.


HIV-1 Reservoirs During Suppressive Therapy.

Barton K, Winckelmann A, Palmer S.

Trends Microbiol. 2016 May;24(5):345-55. doi: 10.1016/j.tim.2016.01.006. Epub 2016 Feb 12. Review.

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