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Items: 1 to 20 of 182


Amyloid-β with isomerized Asp7 cytotoxicity is coupled to protein phosphorylation.

Zatsepina OG, Kechko OI, Mitkevich VA, Kozin SA, Yurinskaya MM, Vinokurov MG, Serebryakova MV, Rezvykh AP, Evgen'ev MB, Makarov AA.

Sci Rep. 2018 Feb 23;8(1):3518. doi: 10.1038/s41598-018-21815-x.


Effects of an Aβ-antibody fragment on Aβ aggregation and astrocytic uptake are modulated by apolipoprotein E and J mimetic peptides.

Montoliu-Gaya L, Mulder SD, Veerhuis R, Villegas S.

PLoS One. 2017 Nov 20;12(11):e0188191. doi: 10.1371/journal.pone.0188191. eCollection 2017.


Phase II clinical trials of anti-amyloid β antibodies: When is enough, enough?

Gold M.

Alzheimers Dement (N Y). 2017 May 17;3(3):402-409. doi: 10.1016/j.trci.2017.04.005. eCollection 2017 Sep. Review.


Cyclic AC253, a novel amylin receptor antagonist, improves cognitive deficits in a mouse model of Alzheimer's disease.

Soudy R, Patel A, Fu W, Kaur K, MacTavish D, Westaway D, Davey R, Zajac J, Jhamandas J.

Alzheimers Dement (N Y). 2016 Dec 10;3(1):44-56. doi: 10.1016/j.trci.2016.11.005. eCollection 2017 Jan.


Calcium signaling and molecular mechanisms underlying neurodegenerative diseases.

Pchitskaya E, Popugaeva E, Bezprozvanny I.

Cell Calcium. 2018 Mar;70:87-94. doi: 10.1016/j.ceca.2017.06.008. Epub 2017 Jun 30. Review.


MicroRNA-195 prevents dendritic degeneration and neuron death in rats following chronic brain hypoperfusion.

Chen X, Jiang XM, Zhao LJ, Sun LL, Yan ML, Tian Y, Zhang S, Duan MJ, Zhao HM, Li WR, Hao YY, Wang LB, Xiong QJ, Ai J.

Cell Death Dis. 2017 Jun 1;8(6):e2850. doi: 10.1038/cddis.2017.243.


Mutation of the Kunitz-type proteinase inhibitor domain in the amyloid β-protein precursor abolishes its anti-thrombotic properties in vivo.

Xu F, Davis J, Hoos M, Van Nostrand WE.

Thromb Res. 2017 Jul;155:58-64. doi: 10.1016/j.thromres.2017.05.003. Epub 2017 May 4.


Crocus sativus Extract Tightens the Blood-Brain Barrier, Reduces Amyloid β Load and Related Toxicity in 5XFAD Mice.

Batarseh YS, Bharate SS, Kumar V, Kumar A, Vishwakarma RA, Bharate SB, Kaddoumi A.

ACS Chem Neurosci. 2017 Aug 16;8(8):1756-1766. doi: 10.1021/acschemneuro.7b00101. Epub 2017 May 15.


Overexpression of matrix metalloproteinase-9 (MMP-9) rescues insulin-mediated impairment in the 5XFAD model of Alzheimer's disease.

Kaminari A, Giannakas N, Tzinia A, Tsilibary EC.

Sci Rep. 2017 Apr 6;7(1):683. doi: 10.1038/s41598-017-00794-5.


Neural stem cell therapy for neurodegenerative disorders: The role of neurotrophic support.

Marsh SE, Blurton-Jones M.

Neurochem Int. 2017 Jun;106:94-100. doi: 10.1016/j.neuint.2017.02.006. Epub 2017 Feb 20. Review.


Amyloidogenicity and toxicity of the reverse and scrambled variants of amyloid-β 1-42.

Vadukul DM, Gbajumo O, Marshall KE, Serpell LC.

FEBS Lett. 2017 Mar;591(5):822-830. doi: 10.1002/1873-3468.12590. Epub 2017 Feb 28.


Hippocampal activation is associated with longitudinal amyloid accumulation and cognitive decline.

Leal SL, Landau SM, Bell RK, Jagust WJ.

Elife. 2017 Feb 8;6. pii: e22978. doi: 10.7554/eLife.22978.


A digital enzyme-linked immunosorbent assay for ultrasensitive measurement of amyloid-β 1-42 peptide in human plasma with utility for studies of Alzheimer's disease therapeutics.

Song L, Lachno DR, Hanlon D, Shepro A, Jeromin A, Gemani D, Talbot JA, Racke MM, Dage JL, Dean RA.

Alzheimers Res Ther. 2016 Dec 15;8(1):58.


Amyloid Dysmetabolism Relates to Reduced Glucose Uptake in White Matter Hyperintensities.

Kalheim LF, Selnes P, Bjørnerud A, Coello C, Vegge K, Fladby T.

Front Neurol. 2016 Nov 21;7:209. eCollection 2016.


Amylin Treatment Reduces Neuroinflammation and Ameliorates Abnormal Patterns of Gene Expression in the Cerebral Cortex of an Alzheimer's Disease Mouse Model.

Wang E, Zhu H, Wang X, Gower AC, Wallack M, Blusztajn JK, Kowall N, Qiu WQ.

J Alzheimers Dis. 2017;56(1):47-61. doi: 10.3233/JAD-160677.


Cytokines and Cytokine Receptors Involved in the Pathogenesis of Alzheimer's Disease.

Nagae T, Araki K, Shimoda Y, Sue LI, Beach TG, Konishi Y.

J Clin Cell Immunol. 2016 Aug;7(4). pii: 441. Epub 2016 Aug 4.


Sex and the development of Alzheimer's disease.

Pike CJ.

J Neurosci Res. 2017 Jan 2;95(1-2):671-680. doi: 10.1002/jnr.23827. Review.


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