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Items: 1 to 20 of 51


Myosin 7 and its adaptors link cadherins to actin.

Yu IM, Planelles-Herrero VJ, Sourigues Y, Moussaoui D, Sirkia H, Kikuti C, Stroebel D, Titus MA, Houdusse A.

Nat Commun. 2017 Jun 29;8:15864. doi: 10.1038/ncomms15864.


The murine catecholamine methyltransferase mTOMT is essential for mechanotransduction by cochlear hair cells.

Cunningham CL, Wu Z, Jafari A, Zhao B, Schrode K, Harkins-Perry S, Lauer A, Müller U.

Elife. 2017 May 15;6. pii: e24318. doi: 10.7554/eLife.24318.


Gene therapy restores auditory and vestibular function in a mouse model of Usher syndrome type 1c.

Pan B, Askew C, Galvin A, Heman-Ackah S, Asai Y, Indzhykulian AA, Jodelka FM, Hastings ML, Lentz JJ, Vandenberghe LH, Holt JR, Géléoc GS.

Nat Biotechnol. 2017 Mar;35(3):264-272. doi: 10.1038/nbt.3801. Epub 2017 Feb 6.


Mechanosensory hair cells express two molecularly distinct mechanotransduction channels.

Wu Z, Grillet N, Zhao B, Cunningham C, Harkins-Perry S, Coste B, Ranade S, Zebarjadi N, Beurg M, Fettiplace R, Patapoutian A, Mueller U.

Nat Neurosci. 2017 Jan;20(1):24-33. doi: 10.1038/nn.4449. Epub 2016 Nov 28.


Stereocilia morphogenesis and maintenance through regulation of actin stability.

McGrath J, Roy P, Perrin BJ.

Semin Cell Dev Biol. 2017 May;65:88-95. doi: 10.1016/j.semcdb.2016.08.017. Epub 2016 Aug 23. Review.


Hair cells use active zones with different voltage dependence of Ca2+ influx to decompose sounds into complementary neural codes.

Ohn TL, Rutherford MA, Jing Z, Jung S, Duque-Afonso CJ, Hoch G, Picher MM, Scharinger A, Strenzke N, Moser T.

Proc Natl Acad Sci U S A. 2016 Aug 9;113(32):E4716-25. doi: 10.1073/pnas.1605737113. Epub 2016 Jul 26.


Murine Fam65b forms ring-like structures at the base of stereocilia critical for mechanosensory hair cell function.

Zhao B, Wu Z, Müller U.

Elife. 2016 Jun 8;5. pii: e14222. doi: 10.7554/eLife.14222.


Cilia-Associated Genes Play Differing Roles in Aminoglycoside-Induced Hair Cell Death in Zebrafish.

Stawicki TM, Hernandez L, Esterberg R, Linbo T, Owens KN, Shah AN, Thapa N, Roberts B, Moens CB, Rubel EW, Raible DW.

G3 (Bethesda). 2016 Jul 7;6(7):2225-35. doi: 10.1534/g3.116.030080.


The zebrafish pinball wizard gene encodes WRB, a tail-anchored-protein receptor essential for inner-ear hair cells and retinal photoreceptors.

Lin SY, Vollrath MA, Mangosing S, Shen J, Cardenas E, Corey DP.

J Physiol. 2016 Feb 15;594(4):895-914. doi: 10.1113/JP271437. Epub 2015 Dec 28.


The elusive mechanotransduction machinery of hair cells.

Zhao B, Müller U.

Curr Opin Neurobiol. 2015 Oct;34:172-9. doi: 10.1016/j.conb.2015.08.006. Epub 2015 Sep 3. Review.


Voltage-Gated Cav1 Channels in Disorders of Vision and Hearing.

Joiner ML, Lee A.

Curr Mol Pharmacol. 2015;8(2):143-8. Review.


Subunit determination of the conductance of hair-cell mechanotransducer channels.

Beurg M, Xiong W, Zhao B, Müller U, Fettiplace R.

Proc Natl Acad Sci U S A. 2015 Feb 3;112(5):1589-94. doi: 10.1073/pnas.1420906112. Epub 2014 Dec 30.


Usher syndrome: Hearing loss, retinal degeneration and associated abnormalities.

Mathur P, Yang J.

Biochim Biophys Acta. 2015 Mar;1852(3):406-20. doi: 10.1016/j.bbadis.2014.11.020. Epub 2014 Dec 4. Review.


TMIE is an essential component of the mechanotransduction machinery of cochlear hair cells.

Zhao B, Wu Z, Grillet N, Yan L, Xiong W, Harkins-Perry S, Müller U.

Neuron. 2014 Dec 3;84(5):954-67. doi: 10.1016/j.neuron.2014.10.041. Epub 2014 Nov 20.


Using injectoporation to deliver genes to mechanosensory hair cells.

Xiong W, Wagner T, Yan L, Grillet N, Müller U.

Nat Protoc. 2014 Oct;9(10):2438-49. doi: 10.1038/nprot.2014.168. Epub 2014 Sep 18.


The physiology of mechanoelectrical transduction channels in hearing.

Fettiplace R, Kim KX.

Physiol Rev. 2014 Jul;94(3):951-86. doi: 10.1152/physrev.00038.2013. Review.


Genetics of auditory mechano-electrical transduction.

Michalski N, Petit C.

Pflugers Arch. 2015 Jan;467(1):49-72. doi: 10.1007/s00424-014-1552-9. Epub 2014 Jun 25. Review.


Intestinal brush border assembly driven by protocadherin-based intermicrovillar adhesion.

Crawley SW, Shifrin DA Jr, Grega-Larson NE, McConnell RE, Benesh AE, Mao S, Zheng Y, Zheng QY, Nam KT, Millis BA, Kachar B, Tyska MJ.

Cell. 2014 Apr 10;157(2):433-446. doi: 10.1016/j.cell.2014.01.067.


Usher protein functions in hair cells and photoreceptors.

Cosgrove D, Zallocchi M.

Int J Biochem Cell Biol. 2014 Jan;46:80-9. doi: 10.1016/j.biocel.2013.11.001. Epub 2013 Nov 12. Review.


Usher proteins in inner ear structure and function.

Ahmed ZM, Frolenkov GI, Riazuddin S.

Physiol Genomics. 2013 Nov 1;45(21):987-9. doi: 10.1152/physiolgenomics.00135.2013. Epub 2013 Sep 10.

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