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Items: 8


The Novel Ribonucleotide Reductase Inhibitor COH29 Inhibits DNA Repair In Vitro.

Chen MC, Zhou B, Zhang K, Yuan YC, Un F, Hu S, Chou CM, Chen CH, Wu J, Wang Y, Liu X, Smith DL, Li H, Liu Z, Warden CD, Su L, Malkas LH, Chung YM, Hu MC, Yen Y.

Mol Pharmacol. 2015 Jun;87(6):996-1005. doi: 10.1124/mol.114.094987. Epub 2015 Mar 26.


Targeting an Achilles' heel of cancer with a WRN helicase inhibitor.

Aggarwal M, Banerjee T, Sommers JA, Brosh RM Jr.

Cell Cycle. 2013 Oct 15;12(20):3329-35. doi: 10.4161/cc.26320. Epub 2013 Sep 12.


Ovarian cancer and DNA repair: DNA ligase IV as a potential key.

Assis J, Pereira D, Medeiros R.

World J Clin Oncol. 2013 Feb 10;4(1):14-24. doi: 10.5306/wjco.v4.i1.14.


Complex DNA repair pathways as possible therapeutic targets to overcome temozolomide resistance in glioblastoma.

Yoshimoto K, Mizoguchi M, Hata N, Murata H, Hatae R, Amano T, Nakamizo A, Sasaki T.

Front Oncol. 2012 Dec 5;2:186. doi: 10.3389/fonc.2012.00186. eCollection 2012.


Exploiting the homologous recombination DNA repair network for targeted cancer therapy.

Peng G, Lin SY.

World J Clin Oncol. 2011 Feb 10;2(2):73-9. doi: 10.5306/wjco.v2.i2.73.


Response of human prostate cancer cells and tumors to combining PARP inhibition with ionizing radiation.

Barreto-Andrade JC, Efimova EV, Mauceri HJ, Beckett MA, Sutton HG, Darga TE, Vokes EE, Posner MC, Kron SJ, Weichselbaum RR.

Mol Cancer Ther. 2011 Jul;10(7):1185-93. doi: 10.1158/1535-7163.MCT-11-0061. Epub 2011 May 13.


Discovery of DNA repair inhibitors by combinatorial library profiling.

Moeller BJ, Sidman RL, Pasqualini R, Arap W.

Cancer Res. 2011 Mar 1;71(5):1816-24. doi: 10.1158/0008-5472.CAN-10-2361. Epub 2011 Feb 22.


Future of personalized medicine in oncology: a systems biology approach.

Gonzalez-Angulo AM, Hennessy BT, Mills GB.

J Clin Oncol. 2010 Jun 1;28(16):2777-83. doi: 10.1200/JCO.2009.27.0777. Epub 2010 Apr 20. Review.

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