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Items: 1 to 20 of 28


Regulation of Wnt/β-catenin signalling by tankyrase-dependent poly(ADP-ribosyl)ation and scaffolding.

Mariotti L, Pollock K, Guettler S.

Br J Pharmacol. 2017 Dec;174(24):4611-4636. doi: 10.1111/bph.14038. Epub 2017 Nov 5. Review.


LNGFR targets the Wnt/β-catenin pathway and promotes the osteogenic differentiation in rat ectomesenchymal stem cells.

Li G, Liu J, Wang Y, Yang K, Zhao M, Xiao Y, Wen X, Liu L.

Sci Rep. 2017 Sep 8;7(1):11021. doi: 10.1038/s41598-017-11555-9.


Wnt/β-catenin signaling pathway inhibits the proliferation and apoptosis of U87 glioma cells via different mechanisms.

Gao L, Chen B, Li J, Yang F, Cen X, Liao Z, Long X.

PLoS One. 2017 Aug 24;12(8):e0181346. doi: 10.1371/journal.pone.0181346. eCollection 2017.


FH535 Suppresses Osteosarcoma Growth In Vitro and Inhibits Wnt Signaling through Tankyrases.

Gustafson CT, Mamo T, Shogren KL, Maran A, Yaszemski MJ.

Front Pharmacol. 2017 May 23;8:285. doi: 10.3389/fphar.2017.00285. eCollection 2017.


Bisleuconothine A, a bisindole alkaloid, inhibits colorectal cancer cell in vitro and in vivo targeting Wnt signaling.

Kong LM, Feng T, Wang YY, Li XY, Ye ZN, An T, Qing C, Luo XD, Li Y.

Oncotarget. 2016 Mar 1;7(9):10203-14. doi: 10.18632/oncotarget.7190.


Lens regeneration from the cornea requires suppression of Wnt/β-catenin signaling.

Hamilton PW, Sun Y, Henry JJ.

Exp Eye Res. 2016 Apr;145:206-215. doi: 10.1016/j.exer.2016.01.003. Epub 2016 Jan 8.


Small-molecule inhibitors of Wnt signaling pathway: towards novel anticancer therapeutics.

Zheng S, Liu J, Wu Y, Huang TL, Wang G.

Future Med Chem. 2015;7(18):2485-505. doi: 10.4155/fmc.15.159. Epub 2015 Dec 16. Review.


Novel β-carbolines inhibit Wnt/β-catenin signaling.

Kong L, Mao B, Zhu H, Li Y.

Cell Death Dis. 2015 Nov 19;6:e1983. doi: 10.1038/cddis.2015.335. No abstract available.


Wnt affects symmetry and morphogenesis during post-embryonic development in colonial chordates.

Di Maio A, Setar L, Tiozzo S, De Tomaso AW.

Evodevo. 2015 May 1;6:17. doi: 10.1186/s13227-015-0009-3. eCollection 2015.


Chondroitin sulfate-E is a negative regulator of a pro-tumorigenic Wnt/beta-catenin-Collagen 1 axis in breast cancer cells.

Willis CM, Klüppel M.

PLoS One. 2014 Aug 4;9(8):e103966. doi: 10.1371/journal.pone.0103966. eCollection 2014.


Wnt inhibition leads to improved chemosensitivity in paediatric acute lymphoblastic leukaemia.

Dandekar S, Romanos-Sirakis E, Pais F, Bhatla T, Jones C, Bourgeois W, Hunger SP, Raetz EA, Hermiston ML, Dasgupta R, Morrison DJ, Carroll WL.

Br J Haematol. 2014 Oct;167(1):87-99. doi: 10.1111/bjh.13011. Epub 2014 Jul 4.


Regulation and regulatory role of WNT signaling in potentiating FSH action during bovine dominant follicle selection.

Gupta PS, Folger JK, Rajput SK, Lv L, Yao J, Ireland JJ, Smith GW.

PLoS One. 2014 Jun 17;9(6):e100201. doi: 10.1371/journal.pone.0100201. eCollection 2014.


Expanding mouse ventricular cardiomyocytes through GSK-3 inhibition.

Buikema JW, Zwetsloot PP, Doevendans PA, Sluijter JP, Domian IJ.

Curr Protoc Cell Biol. 2013 Dec 2;61:23.9.1-23.9.10. doi: 10.1002/0471143030.cb2309s61.


New insights into the regulation of Axin function in canonical Wnt signaling pathway.

Song X, Wang S, Li L.

Protein Cell. 2014 Mar;5(3):186-93. doi: 10.1007/s13238-014-0019-2. Epub 2014 Jan 29. Review.


Preclinical therapeutic efficacy of a novel pharmacologic inducer of apoptosis in malignant peripheral nerve sheath tumors.

Chau V, Lim SK, Mo W, Liu C, Patel AJ, McKay RM, Wei S, Posner BA, De Brabander JK, Williams NS, Parada LF, Le LQ.

Cancer Res. 2014 Jan 15;74(2):586-97. doi: 10.1158/0008-5472.CAN-13-1934. Epub 2013 Nov 27.


Wnt/β-catenin signaling directs the regional expansion of first and second heart field-derived ventricular cardiomyocytes.

Buikema JW, Mady AS, Mittal NV, Atmanli A, Caron L, Doevendans PA, Sluijter JP, Domian IJ.

Development. 2013 Oct;140(20):4165-76. doi: 10.1242/dev.099325. Epub 2013 Sep 11.


Evidence for tankyrases as antineoplastic targets in lung cancer.

Busch AM, Johnson KC, Stan RV, Sanglikar A, Ahmed Y, Dmitrovsky E, Freemantle SJ.

BMC Cancer. 2013 Apr 28;13:211. doi: 10.1186/1471-2407-13-211.


The development of highly potent inhibitors for porcupine.

Wang X, Moon J, Dodge ME, Pan X, Zhang L, Hanson JM, Tuladhar R, Ma Z, Shi H, Williams NS, Amatruda JF, Carroll TJ, Lum L, Chen C.

J Med Chem. 2013 Mar 28;56(6):2700-4. doi: 10.1021/jm400159c. Epub 2013 Mar 19.


Small molecule modulators of Wnt/β-catenin signaling.

Mook RA Jr, Chen M, Lu J, Barak LS, Lyerly HK, Chen W.

Bioorg Med Chem Lett. 2013 Apr 1;23(7):2187-91. doi: 10.1016/j.bmcl.2013.01.101. Epub 2013 Jan 30.

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