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Items: 18

1.

Long-term dynamics of multisite phosphorylation.

Rubinstein BY, Mattingly HH, Berezhkovskii AM, Shvartsman SY.

Mol Biol Cell. 2016 Jul 15;27(14):2331-40. doi: 10.1091/mbc.E16-03-0137.

2.

RAS and downstream RAF-MEK and PI3K-AKT signaling in neuronal development, function and dysfunction.

Zhong J.

Biol Chem. 2016 Mar;397(3):215-22. doi: 10.1515/hsz-2015-0270. Review.

PMID:
26760308
3.

MEK Inhibitors Reverse cAMP-Mediated Anxiety in Zebrafish.

Lundegaard PR, Anastasaki C, Grant NJ, Sillito RR, Zich J, Zeng Z, Paranthaman K, Larsen AP, Armstrong JD, Porteous DJ, Patton EE.

Chem Biol. 2015 Oct 22;22(10):1335-46. doi: 10.1016/j.chembiol.2015.08.010.

4.

RASopathies: unraveling mechanisms with animal models.

Jindal GA, Goyal Y, Burdine RD, Rauen KA, Shvartsman SY.

Dis Model Mech. 2015 Aug 1;8(8):769-82. doi: 10.1242/dmm.020339. Review. Erratum in: Dis Model Mech. 2015 Sep;8(9):1167.

5.

Cardio-facio-cutaneous syndrome: clinical features, diagnosis, and management guidelines.

Pierpont ME, Magoulas PL, Adi S, Kavamura MI, Neri G, Noonan J, Pierpont EI, Reinker K, Roberts AE, Shankar S, Sullivan J, Wolford M, Conger B, Santa Cruz M, Rauen KA.

Pediatrics. 2014 Oct;134(4):e1149-62. doi: 10.1542/peds.2013-3189. Review.

6.

Fish in a Dish: Drug Discovery for Hearing Habilitation.

Esterberg R, Coffin AB, Ou H, Simon JA, Raible DW, Rubel EW.

Drug Discov Today Dis Models. 2013;10(1). doi: 10.1016/j.ddmod.2012.02.001.

7.

Noonan syndrome: comparing mutation-positive with mutation-negative dutch patients.

Croonen EA, Nillesen W, Schrander C, Jongmans M, Scheffer H, Noordam C, Draaisma JM, van der Burgt I, Yntema HG.

Mol Syndromol. 2013 Jun;4(5):227-34. doi: 10.1159/000350686.

8.

The RASopathies.

Rauen KA.

Annu Rev Genomics Hum Genet. 2013;14:355-69. doi: 10.1146/annurev-genom-091212-153523. Review.

9.

Gain-of-function mutations in RIT1 cause Noonan syndrome, a RAS/MAPK pathway syndrome.

Aoki Y, Niihori T, Banjo T, Okamoto N, Mizuno S, Kurosawa K, Ogata T, Takada F, Yano M, Ando T, Hoshika T, Barnett C, Ohashi H, Kawame H, Hasegawa T, Okutani T, Nagashima T, Hasegawa S, Funayama R, Nagashima T, Nakayama K, Inoue S, Watanabe Y, Ogura T, Matsubara Y.

Am J Hum Genet. 2013 Jul 11;93(1):173-80. doi: 10.1016/j.ajhg.2013.05.021.

10.

Retroviral and lentiviral vectors for the induction of immunological tolerance.

Dufait I, Liechtenstein T, Lanna A, Bricogne C, Laranga R, Padella A, Breckpot K, Escors D.

Scientifica (Cairo). 2012 Dec;2012. pii: 694137. No abstract available.

11.

The intermediate-activity (L597V)BRAF mutant acts as an epistatic modifier of oncogenic RAS by enhancing signaling through the RAF/MEK/ERK pathway.

Andreadi C, Cheung LK, Giblett S, Patel B, Jin H, Mercer K, Kamata T, Lee P, Williams A, McMahon M, Marais R, Pritchard C.

Genes Dev. 2012 Sep 1;26(17):1945-58. doi: 10.1101/gad.193458.112.

12.

Continual low-level MEK inhibition ameliorates cardio-facio-cutaneous phenotypes in zebrafish.

Anastasaki C, Rauen KA, Patton EE.

Dis Model Mech. 2012 Jul;5(4):546-52. doi: 10.1242/dmm.008672.

13.

Constitutive activation of B-Raf in the mouse germ line provides a model for human cardio-facio-cutaneous syndrome.

Urosevic J, Sauzeau V, Soto-Montenegro ML, Reig S, Desco M, Wright EM, CaƱamero M, Mulero F, Ortega S, Bustelo XR, Barbacid M.

Proc Natl Acad Sci U S A. 2011 Mar 22;108(12):5015-20. doi: 10.1073/pnas.1016933108.

14.

Noonan syndrome gain-of-function mutations in NRAS cause zebrafish gastrulation defects.

Runtuwene V, van Eekelen M, Overvoorde J, Rehmann H, Yntema HG, Nillesen WM, van Haeringen A, van der Burgt I, Burgering B, den Hertog J.

Dis Model Mech. 2011 May;4(3):393-9. doi: 10.1242/dmm.007112.

15.

Combined zebrafish-yeast chemical-genetic screens reveal gene-copper-nutrition interactions that modulate melanocyte pigmentation.

Ishizaki H, Spitzer M, Wildenhain J, Anastasaki C, Zeng Z, Dolma S, Shaw M, Madsen E, Gitlin J, Marais R, Tyers M, Patton EE.

Dis Model Mech. 2010 Sep-Oct;3(9-10):639-51. doi: 10.1242/dmm.005769.

16.

Small molecule screening in zebrafish: an in vivo approach to identifying new chemical tools and drug leads.

Taylor KL, Grant NJ, Temperley ND, Patton EE.

Cell Commun Signal. 2010 Jun 12;8:11. doi: 10.1186/1478-811X-8-11.

17.

Genetic and environmental melanoma models in fish.

Patton EE, Mitchell DL, Nairn RS.

Pigment Cell Melanoma Res. 2010 Jun;23(3):314-37. doi: 10.1111/j.1755-148X.2010.00693.x. Review.

18.

The RASopathies: developmental syndromes of Ras/MAPK pathway dysregulation.

Tidyman WE, Rauen KA.

Curr Opin Genet Dev. 2009 Jun;19(3):230-6. doi: 10.1016/j.gde.2009.04.001. Review.

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