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Role of microRNAs in inflammation-associated liver cancer.

Huan L, Liang LH, He XH.

Cancer Biol Med. 2016 Dec;13(4):407-425. doi: 10.20892/j.issn.2095-3941.2016.0071.


Exome and genome sequencing of nasopharynx cancer identifies NF-κB pathway activating mutations.

Li YY, Chung GT, Lui VW, To KF, Ma BB, Chow C, Woo JK, Yip KY, Seo J, Hui EP, Mak MK, Rusan M, Chau NG, Or YY, Law MH, Law PP, Liu ZW, Ngan HL, Hau PM, Verhoeft KR, Poon PH, Yoo SK, Shin JY, Lee SD, Lun SW, Jia L, Chan AW, Chan JY, Lai PB, Fung CY, Hung ST, Wang L, Chang AM, Chiosea SI, Hedberg ML, Tsao SW, van Hasselt AC, Chan AT, Grandis JR, Hammerman PS, Lo KW.

Nat Commun. 2017 Jan 18;8:14121. doi: 10.1038/ncomms14121.


MALT1 Protease Activation Triggers Acute Disruption of Endothelial Barrier Integrity via CYLD Cleavage.

Klei LR, Hu D, Panek R, Alfano DN, Bridwell RE, Bailey KM, Oravecz-Wilson KI, Concel VJ, Hess EM, Van Beek M, Delekta PC, Gu S, Watkins SC, Ting AT, Gough PJ, Foley KP, Bertin J, McAllister-Lucas LM, Lucas PC.

Cell Rep. 2016 Sep 27;17(1):221-32. doi: 10.1016/j.celrep.2016.08.080.


Whole-exome sequencing identifies multiple loss-of-function mutations of NF-κB pathway regulators in nasopharyngeal carcinoma.

Zheng H, Dai W, Cheung AK, Ko JM, Kan R, Wong BW, Leong MM, Deng M, Kwok TC, Chan JY, Kwong DL, Lee AW, Ng WT, Ngan RK, Yau CC, Tung S, Lee VH, Lam KO, Kwan CK, Li WS, Yau S, Chan KW, Lung ML.

Proc Natl Acad Sci U S A. 2016 Oct 4;113(40):11283-11288. Epub 2016 Sep 19.


SPATA2: New insights into the assembly of the TNFR signaling complex.

Schlicher L, Maurer U.

Cell Cycle. 2017 Jan 2;16(1):11-12. doi: 10.1080/15384101.2016.1232090. Epub 2016 Sep 16. No abstract available.


MYCN promotes neuroblastoma malignancy by establishing a regulatory circuit with transcription factor AP4.

Xue C, Yu DM, Gherardi S, Koach J, Milazzo G, Gamble L, Liu B, Valli E, Russell AJ, London WB, Liu T, Cheung BB, Marshall GM, Perini G, Haber M, Norris MD.

Oncotarget. 2016 Aug 23;7(34):54937-54951. doi: 10.18632/oncotarget.10709.


miR-130b, an onco-miRNA in bladder cancer, is directly regulated by NF-κB and sustains NF-κB activation by decreasing Cylindromatosis expression.

Cui X, Kong C, Zhu Y, Zeng Y, Zhang Z, Liu X, Zhan B, Piao C, Jiang Z.

Oncotarget. 2016 Jul 26;7(30):48547-48561. doi: 10.18632/oncotarget.10423.


The paracaspase MALT1 mediates CARD14-induced signaling in keratinocytes.

Afonina IS, Van Nuffel E, Baudelet G, Driege Y, Kreike M, Staal J, Beyaert R.

EMBO Rep. 2016 Jun;17(6):914-27. doi: 10.15252/embr.201642109. Epub 2016 Apr 25.


High LEF1 expression predicts adverse prognosis in chronic lymphocytic leukemia and may be targeted by ethacrynic acid.

Wu W, Zhu H, Fu Y, Shen W, Miao K, Hong M, Xu W, Fan L, Young KH, Liu P, Li J.

Oncotarget. 2016 Apr 19;7(16):21631-43. doi: 10.18632/oncotarget.7795.


Autophagy in acute kidney injury.

Kaushal GP, Shah SV.

Kidney Int. 2016 Apr;89(4):779-91. doi: 10.1016/j.kint.2015.11.021. Epub 2016 Jan 21. Review.


Downregulation of miR-362-5p inhibits proliferation, migration and invasion of human breast cancer MCF7 cells.

Ni F, Gui Z, Guo Q, Hu Z, Wang X, Chen D, Wang S.

Oncol Lett. 2016 Feb;11(2):1155-1160. Epub 2015 Dec 3.


Receptor-Interacting Protein Kinase-2 Inhibition by CYLD Impairs Antibacterial Immune Responses in Macrophages.

Wex K, Schmid U, Just S, Wang X, Wurm R, Naumann M, Schlüter D, Nishanth G.

Front Immunol. 2016 Jan 19;6:650. doi: 10.3389/fimmu.2015.00650. eCollection 2015.


Hepatocellular carcinoma mouse models: Hepatitis B virus-associated hepatocarcinogenesis and haploinsufficient tumor suppressor genes.

Teng YC, Shen ZQ, Kao CH, Tsai TF.

World J Gastroenterol. 2016 Jan 7;22(1):300-25. doi: 10.3748/wjg.v22.i1.300. Review.


NF-κB in inflammation and renal diseases.

Zhang H, Sun SC.

Cell Biosci. 2015 Nov 16;5:63. doi: 10.1186/s13578-015-0056-4. eCollection 2015. Review.


Regulation of Met1-linked polyubiquitin signalling by the deubiquitinase OTULIN.

Elliott PR, Komander D.

FEBS J. 2016 Jan;283(1):39-53. doi: 10.1111/febs.13547. Epub 2015 Nov 2. Review.


A Structural View of Negative Regulation of the Toll-like Receptor-Mediated Inflammatory Pathway.

Guven-Maiorov E, Keskin O, Gursoy A, Nussinov R.

Biophys J. 2015 Sep 15;109(6):1214-26. doi: 10.1016/j.bpj.2015.06.048. Epub 2015 Aug 11.


Roles of miR-182 in sensory organ development and cancer.

Wei Q, Lei R, Hu G.

Thorac Cancer. 2015 Jan;6(1):2-9. doi: 10.1111/1759-7714.12164. Epub 2015 Jan 7. Review.


TCR signaling to NF-κB and mTORC1: Expanding roles of the CARMA1 complex.

Shi JH, Sun SC.

Mol Immunol. 2015 Dec;68(2 Pt C):546-57. doi: 10.1016/j.molimm.2015.07.024. Epub 2015 Aug 8. Review.


Linear ubiquitination signals in adaptive immune responses.

Ikeda F.

Immunol Rev. 2015 Jul;266(1):222-36. doi: 10.1111/imr.12300. Review.


Linear ubiquitination in immunity.

Shimizu Y, Taraborrelli L, Walczak H.

Immunol Rev. 2015 Jul;266(1):190-207. doi: 10.1111/imr.12309. Review.

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