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ANO1 inhibits cardiac fibrosis after myocardial infraction via TGF-β/smad3 pathway.

Gao Y, Zhang YM, Qian LJ, Chu M, Hong J, Xu D.

Sci Rep. 2017 May 24;7(1):2355. doi: 10.1038/s41598-017-02585-4.


Association between hyperpolarization-activated channel in interstitial cells of Cajal and gastrointestinal dysmotility induced by malignant ascites.

Guo T, Li J, Li J, Kong D, Bi C, He Z, Tang D, Jin X, Jin L.

Oncol Lett. 2017 Mar;13(3):1601-1608. doi: 10.3892/ol.2017.5652. Epub 2017 Jan 25.


Transcriptome of interstitial cells of Cajal reveals unique and selective gene signatures.

Lee MY, Ha SE, Park C, Park PJ, Fuchs R, Wei L, Jorgensen BG, Redelman D, Ward SM, Sanders KM, Ro S.

PLoS One. 2017 Apr 20;12(4):e0176031. doi: 10.1371/journal.pone.0176031. eCollection 2017.


Is the muscular tone of the internal anal sphincter a property of the syncytium?

Jimenez M.

J Physiol. 2017 Mar 15;595(6):1853-1854. doi: 10.1113/JP273999. Epub 2017 Feb 22. No abstract available.


Calcium Signaling in Interstitial Cells: Focus on Telocytes.

Radu BM, Banciu A, Banciu DD, Radu M, Cretoiu D, Cretoiu SM.

Int J Mol Sci. 2017 Feb 13;18(2). pii: E397. doi: 10.3390/ijms18020397. Review.


Electroacupuncture at ST36 Protects ICC Networks via mSCF/Kit-ETV1 Signaling in the Stomach of Diabetic Mice.

Tian L, Zhu B, Liu S.

Evid Based Complement Alternat Med. 2017;2017:3980870. doi: 10.1155/2017/3980870. Epub 2017 Jan 22.


TMEM16A/ANO1 suppression improves response to antibody-mediated targeted therapy of EGFR and HER2/ERBB2.

Kulkarni S, Bill A, Godse NR, Khan NI, Kass JI, Steehler K, Kemp C, Davis K, Bertrand CA, Vyas AR, Holt DE, Grandis JR, Gaither LA, Duvvuri U.

Genes Chromosomes Cancer. 2017 Jun;56(6):460-471. doi: 10.1002/gcc.22450. Epub 2017 Apr 3.


ANO1 in intramuscular interstitial cells of Cajal plays a key role in the generation of slow waves and tone in the internal anal sphincter.

Cobine CA, Hannah EE, Zhu MH, Lyle HE, Rock JR, Sanders KM, Ward SM, Keef KD.

J Physiol. 2017 Mar 15;595(6):2021-2041. doi: 10.1113/JP273618. Epub 2017 Feb 14.


The stem cell growth factor receptor KIT is not expressed on interstitial cells in bladder.

Gevaert T, Ridder D, Vanstreels E, Daelemans D, Everaerts W, Aa FV, Pintelon I, Timmermans JP, Roskams T, Steiner C, Neuhaus J.

J Cell Mol Med. 2017 Jun;21(6):1206-1216. doi: 10.1111/jcmm.13054. Epub 2016 Dec 20.


Conditional genetic deletion of Ano1 in interstitial cells of Cajal impairs Ca2+ transients and slow waves in adult mouse small intestine.

Malysz J, Gibbons SJ, Saravanaperumal SA, Du P, Eisenman ST, Cao C, Oh U, Saur D, Klein S, Ordog T, Farrugia G.

Am J Physiol Gastrointest Liver Physiol. 2017 Mar 1;312(3):G228-G245. doi: 10.1152/ajpgi.00363.2016. Epub 2016 Dec 15.


Mechanisms of Electrical Activation and Conduction in the Gastrointestinal System: Lessons from Cardiac Electrophysiology.

Tse G, Lai ET, Yeo JM, Tse V, Wong SH.

Front Physiol. 2016 May 31;7:182. doi: 10.3389/fphys.2016.00182. eCollection 2016. Review.


Novel Use for DOG1 in Discriminating Breast Invasive Carcinoma from Noninvasive Breast Lesions.

Cheng H, Yang S, Qu Z, Zhou S, Ruan Q.

Dis Markers. 2016;2016:5628176. doi: 10.1155/2016/5628176. Epub 2016 Mar 2.


Spontaneous Ca(2+) transients in interstitial cells of Cajal located within the deep muscular plexus of the murine small intestine.

Baker SA, Drumm BT, Saur D, Hennig GW, Ward SM, Sanders KM.

J Physiol. 2016 Jun 15;594(12):3317-38. doi: 10.1113/JP271699. Epub 2016 Mar 11.


Effects of new-generation inhibitors of the calcium-activated chloride channel anoctamin 1 on slow waves in the gastrointestinal tract.

Hwang SJ, Basma N, Sanders KM, Ward SM.

Br J Pharmacol. 2016 Apr;173(8):1339-49. doi: 10.1111/bph.13431. Epub 2016 Mar 6.


Spontaneous activity in the microvasculature of visceral organs: role of pericytes and voltage-dependent Ca(2+) channels.

Hashitani H, Lang RJ.

J Physiol. 2016 Feb 1;594(3):555-65. doi: 10.1113/JP271438. Epub 2016 Jan 6. Review.


The virtual intestine: in silico modeling of small intestinal electrophysiology and motility and the applications.

Du P, Paskaranandavadivel N, Angeli TR, Cheng LK, O'Grady G.

Wiley Interdiscip Rev Syst Biol Med. 2016 Jan-Feb;8(1):69-85. doi: 10.1002/wsbm.1324. Epub 2015 Nov 12. Review.


Walker 256 tumor-bearing rats demonstrate altered interstitial cells of Cajal. Effects on ICC in the Walker 256 tumor model.

Fracaro L, Frez FC, Silva BC, Vicentini GE, de Souza SR, Martins HA, Linden DR, Guarnier FA, Zanoni JN.

Neurogastroenterol Motil. 2016 Jan;28(1):101-15. doi: 10.1111/nmo.12702. Epub 2015 Nov 3.


Targeting Ion Channels: An Important Therapeutic Implication in Gastrointestinal Dysmotility in Patients With Spinal Cord Injury.

Radulovic M, Anand P, Korsten MA, Gong B.

J Neurogastroenterol Motil. 2015 Oct 1;21(4):494-502. doi: 10.5056/jnm15061.


A novel exon in the human Ca2+-activated Cl- channel Ano1 imparts greater sensitivity to intracellular Ca2.

Strege PR, Bernard CE, Mazzone A, Linden DR, Beyder A, Gibbons SJ, Farrugia G.

Am J Physiol Gastrointest Liver Physiol. 2015 Nov 1;309(9):G743-9. doi: 10.1152/ajpgi.00074.2015. Epub 2015 Sep 10.


The impact of inflammatory cells in malignant ascites on small intestinal ICCs' morphology and function.

Li J, Kong D, He Y, Wang X, Gao L, Li J, Yan M, Liu D, Wang Y, Zhang L, Jin X.

J Cell Mol Med. 2015 Sep;19(9):2118-27. doi: 10.1111/jcmm.12575. Epub 2015 Jun 18.

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