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Chrysophanic Acid Suppresses Adipogenesis and Induces Thermogenesis by Activating AMP-Activated Protein Kinase Alpha In vivo and In vitro.

Lim H, Park J, Kim HL, Kang J, Jeong MY, Youn DH, Jung Y, Kim YI, Kim HJ, Ahn KS, Kim SJ, Choe SK, Hong SH, Um JY.

Front Pharmacol. 2016 Dec 8;7:476. doi: 10.3389/fphar.2016.00476.


Rose hip supplementation increases energy expenditure and induces browning of white adipose tissue.

Cavalera M, Axling U, Berger K, Holm C.

Nutr Metab (Lond). 2016 Dec 6;13:91.


Comparative Transcriptomic and Epigenomic Analyses Reveal New Regulators of Murine Brown Adipogenesis.

Brunmeir R, Wu J, Peng X, Kim SY, Julien SG, Zhang Q, Xie W, Xu F.

PLoS Genet. 2016 Dec 6;12(12):e1006474. doi: 10.1371/journal.pgen.1006474.


mTORC1 is Required for Brown Adipose Tissue Recruitment and Metabolic Adaptation to Cold.

Labbé SM, Mouchiroud M, Caron A, Secco B, Freinkman E, Lamoureux G, Gélinas Y, Lecomte R, Bossé Y, Chimin P, Festuccia WT, Richard D, Laplante M.

Sci Rep. 2016 Nov 23;6:37223. doi: 10.1038/srep37223.


Regional brain responses in humans during body heating and cooling.

Farrell MJ.

Temperature (Austin). 2016 Apr 13;3(2):220-231. Review.


Activation of β3-adrenoceptors increases in vivo free fatty acid uptake and utilization in brown but not white fat depots in high-fat-fed rats.

Warner A, Kjellstedt A, Carreras A, Böttcher G, Peng XR, Seale P, Oakes N, Lindén D.

Am J Physiol Endocrinol Metab. 2016 Dec 1;311(6):E901-E910. doi: 10.1152/ajpendo.00204.2016.


Mitochondrial Activity in Human White Adipocytes Is Regulated by the Ubiquitin Carrier Protein 9/microRNA-30a Axis.

Koh EH, Chen Y, Bader DA, Hamilton MP, He B, York B, Kajimura S, McGuire SE, Hartig SM.

J Biol Chem. 2016 Nov 18;291(47):24747-24755.


Brown Adipose Tissue Function Is Enhanced in Long-Lived, Male Ames Dwarf Mice.

Darcy J, McFadden S, Fang Y, Huber JA, Zhang C, Sun LY, Bartke A.

Endocrinology. 2016 Dec;157(12):4744-4753.


Bariatric surgery and type 2 diabetes: are there weight loss-independent therapeutic effects of upper gastrointestinal bypass?

Chondronikola M, Harris LL, Klein S.

J Intern Med. 2016 Nov;280(5):476-486. doi: 10.1111/joim.12527.


Pharmacologic activation of estrogen receptor β increases mitochondrial function, energy expenditure, and brown adipose tissue.

Ponnusamy S, Tran QT, Harvey I, Smallwood HS, Thiyagarajan T, Banerjee S, Johnson DL, Dalton JT, Sullivan RD, Miller DD, Bridges D, Narayanan R.

FASEB J. 2017 Jan;31(1):266-281. doi: 10.1096/fj.201600787RR.


Fat tissues, the brite and the dark sides.

Chen Y, Pan R, Pfeifer A.

Pflugers Arch. 2016 Nov;468(11-12):1803-1807. Review.


Gene pathway development in human epicardial adipose tissue during early life.

Ojha S, Fainberg HP, Wilson V, Pelella G, Castellanos M, May ST, Lotto AA, Sacks H, Symonds ME, Budge H.

JCI Insight. 2016 Aug 18;1(13):e87460.


Epigenetic Regulation of the Thermogenic Adipose Program.

Sambeat A, Gulyaeva O, Dempersmier J, Sul HS.

Trends Endocrinol Metab. 2017 Jan;28(1):19-31. doi: 10.1016/j.tem.2016.09.003. Review.


Dynamic DNA methylation landscape defines brown and white cell specificity during adipogenesis.

Lim YC, Chia SY, Jin S, Han W, Ding C, Sun L.

Mol Metab. 2016 Aug 17;5(10):1033-41. doi: 10.1016/j.molmet.2016.08.006.


Maternal high-fat diet during lactation impairs thermogenic function of brown adipose tissue in offspring mice.

Liang X, Yang Q, Zhang L, Maricelli JW, Rodgers BD, Zhu MJ, Du M.

Sci Rep. 2016 Sep 30;6:34345. doi: 10.1038/srep34345.


Deficiency of Interleukin-15 Confers Resistance to Obesity by Diminishing Inflammation and Enhancing the Thermogenic Function of Adipose Tissues.

Lacraz G, Rakotoarivelo V, Labbé SM, Vernier M, Noll C, Mayhue M, Stankova J, Schwertani A, Grenier G, Carpentier A, Richard D, Ferbeyre G, Fradette J, Rola-Pleszczynski M, Menendez A, Langlois MF, Ilangumaran S, Ramanathan S.

PLoS One. 2016 Sep 29;11(9):e0162995. doi: 10.1371/journal.pone.0162995. Erratum in: PLoS One. 2016 Nov 8;11(11):e0166537.


Calcium Sensing Receptor as a Novel Mediator of Adipose Tissue Dysfunction: Mechanisms and Potential Clinical Implications.

Bravo-Sagua R, Mattar P, Díaz X, Lavandero S, Cifuentes M.

Front Physiol. 2016 Sep 8;7:395. doi: 10.3389/fphys.2016.00395. Review.


miR-125b affects mitochondrial biogenesis and impairs brite adipocyte formation and function.

Giroud M, Pisani DF, Karbiener M, Barquissau V, Ghandour RA, Tews D, Fischer-Posovszky P, Chambard JC, Knippschild U, Niemi T, Taittonen M, Nuutila P, Wabitsch M, Herzig S, Virtanen KA, Langin D, Scheideler M, Amri EZ.

Mol Metab. 2016 Jun 15;5(8):615-25. doi: 10.1016/j.molmet.2016.06.005.


AMPK/α-Ketoglutarate Axis Dynamically Mediates DNA Demethylation in the Prdm16 Promoter and Brown Adipogenesis.

Yang Q, Liang X, Sun X, Zhang L, Fu X, Rogers CJ, Berim A, Zhang S, Wang S, Wang B, Foretz M, Viollet B, Gang DR, Rodgers BD, Zhu MJ, Du M.

Cell Metab. 2016 Oct 11;24(4):542-554. doi: 10.1016/j.cmet.2016.08.010.

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