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Items: 1 to 20 of 35


CYC1 Predicts Poor Prognosis in Patients with Breast Cancer.

Han Y, Sun S, Zhao M, Zhang Z, Gong S, Gao P, Liu J, Zhou J, Ma D, Gao Q, Wu P.

Dis Markers. 2016;2016:3528064. doi: 10.1155/2016/3528064. Epub 2016 Apr 28.


LKB1/AMPK inhibits TGF-β1 production and the TGF-β signaling pathway in breast cancer cells.

Li NS, Zou JR, Lin H, Ke R, He XL, Xiao L, Huang D, Luo L, Lv N, Luo Z.

Tumour Biol. 2016 Jun;37(6):8249-58. doi: 10.1007/s13277-015-4639-9. Epub 2015 Dec 30.


Mitochondrial Dysfunction Induces Senescence with a Distinct Secretory Phenotype.

Wiley CD, Velarde MC, Lecot P, Liu S, Sarnoski EA, Freund A, Shirakawa K, Lim HW, Davis SS, Ramanathan A, Gerencser AA, Verdin E, Campisi J.

Cell Metab. 2016 Feb 9;23(2):303-14. doi: 10.1016/j.cmet.2015.11.011. Epub 2015 Dec 10.


AMPK Inhibits the Stimulatory Effects of TGF-β on Smad2/3 Activity, Cell Migration, and Epithelial-to-Mesenchymal Transition.

Lin H, Li N, He H, Ying Y, Sunkara S, Luo L, Lv N, Huang D, Luo Z.

Mol Pharmacol. 2015 Dec;88(6):1062-71. doi: 10.1124/mol.115.099549. Epub 2015 Sep 30.


Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL)-Troglitazone-induced Apoptosis in Prostate Cancer Cells Involve AMP-activated Protein Kinase.

Santha S, Viswakarma N, Das S, Rana A, Rana B.

J Biol Chem. 2015 Sep 4;290(36):21865-75. doi: 10.1074/jbc.M115.663526. Epub 2015 Jul 21.


MLK3 phophorylates AMPK independently of LKB1.

Luo L, Jiang S, Huang D, Lu N, Luo Z.

PLoS One. 2015 Apr 13;10(4):e0123927. doi: 10.1371/journal.pone.0123927. eCollection 2015.


Mitochondrial effectors of cellular senescence: beyond the free radical theory of aging.

Ziegler DV, Wiley CD, Velarde MC.

Aging Cell. 2015 Feb;14(1):1-7. doi: 10.1111/acel.12287. Epub 2014 Nov 14. Review.


AMPKα1 deficiency promotes cellular proliferation and DNA damage via p21 reduction in mouse embryonic fibroblasts.

Xu H, Zhou Y, Coughlan KA, Ding Y, Wang S, Wu Y, Song P, Zou MH.

Biochim Biophys Acta. 2015 Jan;1853(1):65-73. doi: 10.1016/j.bbamcr.2014.10.002. Epub 2014 Oct 13.


Transcriptomic analysis reveals inhibition of androgen receptor activity by AMPK in prostate cancer cells.

Jurmeister S, Ramos-Montoya A, Neal DE, Fryer LG.

Oncotarget. 2014 Jun 15;5(11):3785-99.


Histone/protein deacetylase SIRT1 is an anticancer therapeutic target.

Hwang BJ, Madabushi A, Jin J, Lin SY, Lu AL.

Am J Cancer Res. 2014 May 26;4(3):211-21. eCollection 2014.


Modulation by metformin of molecular and histopathological alterations in the lung of cigarette smoke-exposed mice.

Izzotti A, Balansky R, D'Agostini F, Longobardi M, Cartiglia C, Micale RT, La Maestra S, Camoirano A, Ganchev G, Iltcheva M, Steele VE, De Flora S.

Cancer Med. 2014 Jun;3(3):719-30. doi: 10.1002/cam4.234. Epub 2014 Mar 28.


Metformin anti-tumor effect via disruption of the MID1 translational regulator complex and AR downregulation in prostate cancer cells.

Demir U, Koehler A, Schneider R, Schweiger S, Klocker H.

BMC Cancer. 2014 Jan 31;14:52. doi: 10.1186/1471-2407-14-52.


AMP-Activated Protein Kinase α 2 Isoform Suppression in Primary Breast Cancer Alters AMPK Growth Control and Apoptotic Signaling.

Fox MM, Phoenix KN, Kopsiaftis SG, Claffey KP.

Genes Cancer. 2013 Jan;4(1-2):3-14. doi: 10.1177/1947601913486346.


AMPK as a potential anticancer target - friend or foe?

Chuang HC, Chou CC, Kulp SK, Chen CS.

Curr Pharm Des. 2014;20(15):2607-18. Review.


Reversing the Warburg effect as a treatment for glioblastoma.

Poteet E, Choudhury GR, Winters A, Li W, Ryou MG, Liu R, Tang L, Ghorpade A, Wen Y, Yuan F, Keir ST, Yan H, Bigner DD, Simpkins JW, Yang SH.

J Biol Chem. 2013 Mar 29;288(13):9153-64. doi: 10.1074/jbc.M112.440354. Epub 2013 Feb 13.


Knockdown of AMP-activated protein kinase alpha 1 and alpha 2 catalytic subunits.

Tangeman L, Wyatt CN, Brown TL.

J RNAi Gene Silencing. 2012;8:470-8. Epub 2012 Oct 4.


AMPK activators suppress cervical cancer cell growth through inhibition of DVL3 mediated Wnt/β-catenin signaling activity.

Kwan HT, Chan DW, Cai PC, Mak CS, Yung MM, Leung TH, Wong OG, Cheung AN, Ngan HY.

PLoS One. 2013;8(1):e53597. doi: 10.1371/journal.pone.0053597. Epub 2013 Jan 2.


The effect of metformin and thiazolidinedione use on lung cancer in diabetics.

Mazzone PJ, Rai H, Beukemann M, Xu M, Jain A, Sasidhar M.

BMC Cancer. 2012 Sep 14;12:410. doi: 10.1186/1471-2407-12-410.


ATM and LKB1 dependent activation of AMPK sensitizes cancer cells to etoposide-induced apoptosis.

Luo L, Huang W, Tao R, Hu N, Xiao ZX, Luo Z.

Cancer Lett. 2013 Jan 1;328(1):114-9. doi: 10.1016/j.canlet.2012.08.034. Epub 2012 Sep 5.

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