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Items: 1 to 20 of 22

1.
2.

Myt3 suppression sensitizes islet cells to high glucose-induced cell death via Bim induction.

Tennant BR, Vanderkruk B, Dhillon J, Dai D, Verchere CB, Hoffman BG.

Cell Death Dis. 2016 May 19;7:e2233. doi: 10.1038/cddis.2016.141.

3.

Molecular Events Linking Oxidative Stress and Inflammation to Insulin Resistance and β-Cell Dysfunction.

Keane KN, Cruzat VF, Carlessi R, de Bittencourt PI Jr, Newsholme P.

Oxid Med Cell Longev. 2015;2015:181643. doi: 10.1155/2015/181643. Epub 2015 Jul 14. Review.

4.

Reversal of diabetes following transplantation of an insulin-secreting human liver cell line: Melligen cells.

Lawandi J, Tao C, Ren B, Williams P, Ling D, Swan MA, Nassif NT, Torpy FR, O'Brien BA, Simpson AM.

Mol Ther Methods Clin Dev. 2015 Apr 8;2:15011. doi: 10.1038/mtm.2015.11. eCollection 2015.

5.

Targeting inflammation in diabetes: Newer therapeutic options.

Agrawal NK, Kant S.

World J Diabetes. 2014 Oct 15;5(5):697-710. doi: 10.4239/wjd.v5.i5.697. Review.

6.

CEBPA exerts a specific and biologically important proapoptotic role in pancreatic β cells through its downstream network targets.

Barbagallo D, Condorelli AG, Piro S, Parrinello N, Fløyel T, Ragusa M, Rabuazzo AM, Størling J, Purrello F, Di Pietro C, Purrello M.

Mol Biol Cell. 2014 Aug 15;25(16):2333-41. doi: 10.1091/mbc.E14-02-0703. Epub 2014 Jun 18.

7.

METTL21C is a potential pleiotropic gene for osteoporosis and sarcopenia acting through the modulation of the NF-κB signaling pathway.

Huang J, Hsu YH, Mo C, Abreu E, Kiel DP, Bonewald LF, Brotto M, Karasik D.

J Bone Miner Res. 2014 Jul;29(7):1531-40. doi: 10.1002/jbmr.2200.

8.

Genetically modified human bone marrow derived mesenchymal stem cells for improving the outcome of human islet transplantation.

Mundra V, Wu H, Mahato RI.

PLoS One. 2013 Oct 29;8(10):e77591. doi: 10.1371/journal.pone.0077591. eCollection 2013.

9.

The pancreatic β cell and type 1 diabetes: innocent bystander or active participant?

Soleimanpour SA, Stoffers DA.

Trends Endocrinol Metab. 2013 Jul;24(7):324-31. doi: 10.1016/j.tem.2013.03.005. Epub 2013 May 3.

10.

The C-terminal domain of A1/Bfl-1 regulates its anti-inflammatory function in human endothelial cells.

Guedes RP, Rocha E, Mahiou J, Moll HP, Arvelo MB, Taube JM, Peterson CR, Kaczmarek E, Longo CR, da Silva CG, Ferran C.

Biochim Biophys Acta. 2013 Jun;1833(6):1553-61. doi: 10.1016/j.bbamcr.2013.03.001. Epub 2013 Mar 13.

11.

The adipocytokine Nampt and its product NMN have no effect on beta-cell survival but potentiate glucose stimulated insulin secretion.

Spinnler R, Gorski T, Stolz K, Schuster S, Garten A, Beck-Sickinger AG, Engelse MA, de Koning EJ, Körner A, Kiess W, Maedler K.

PLoS One. 2013;8(1):e54106. doi: 10.1371/journal.pone.0054106. Epub 2013 Jan 16.

12.

Multiparametric analyses of human PBMCs loaded ex vivo with a candidate idiotype vaccine for HCV-related lymphoproliferative disorders.

Petrizzo A, Tornesello ML, Napolitano M, D'Alessio G, Salomone Megna A, Dolcetti R, De Re V, Wang E, Marincola FM, Buonaguro FM, Buonaguro L.

PLoS One. 2012;7(9):e44870. doi: 10.1371/journal.pone.0044870. Epub 2012 Sep 18.

13.

Inflammation-Mediated Regulation of MicroRNA Expression in Transplanted Pancreatic Islets.

Bravo-Egana V, Rosero S, Klein D, Jiang Z, Vargas N, Tsinoremas N, Doni M, Podetta M, Ricordi C, Molano RD, Pileggi A, Pastori RL.

J Transplant. 2012;2012:723614. doi: 10.1155/2012/723614. Epub 2012 May 10.

14.

The human pancreatic islet transcriptome: expression of candidate genes for type 1 diabetes and the impact of pro-inflammatory cytokines.

Eizirik DL, Sammeth M, Bouckenooghe T, Bottu G, Sisino G, Igoillo-Esteve M, Ortis F, Santin I, Colli ML, Barthson J, Bouwens L, Hughes L, Gregory L, Lunter G, Marselli L, Marchetti P, McCarthy MI, Cnop M.

PLoS Genet. 2012;8(3):e1002552. doi: 10.1371/journal.pgen.1002552. Epub 2012 Mar 8.

15.

Analysis of beta-cell gene expression reveals inflammatory signaling and evidence of dedifferentiation following human islet isolation and culture.

Negi S, Jetha A, Aikin R, Hasilo C, Sladek R, Paraskevas S.

PLoS One. 2012;7(1):e30415. doi: 10.1371/journal.pone.0030415. Epub 2012 Jan 27.

16.

Expression and regulation of chemokines in murine and human type 1 diabetes.

Sarkar SA, Lee CE, Victorino F, Nguyen TT, Walters JA, Burrack A, Eberlein J, Hildemann SK, Homann D.

Diabetes. 2012 Feb;61(2):436-46. doi: 10.2337/db11-0853. Epub 2011 Dec 30.

17.

cJUN N-terminal kinase (JNK) activation mediates islet amyloid-induced beta cell apoptosis in cultured human islet amyloid polypeptide transgenic mouse islets.

Subramanian SL, Hull RL, Zraika S, Aston-Mourney K, Udayasankar J, Kahn SE.

Diabetologia. 2012 Jan;55(1):166-74. doi: 10.1007/s00125-011-2338-7. Epub 2011 Oct 26.

18.

Uncoupling protein-2 increases nitric oxide production and TNFAIP3 pathway activation in pancreatic islets.

Niño Fong R, Fatehi-Hassanabad Z, Lee SC, Lu H, Wheeler MB, Chan CB.

J Mol Endocrinol. 2011 Apr 15;46(3):193-204. doi: 10.1530/JME-10-0117. Print 2011 Jun.

19.

Phagocyte-like NADPH oxidase promotes cytokine-induced mitochondrial dysfunction in pancreatic β-cells: evidence for regulation by Rac1.

Subasinghe W, Syed I, Kowluru A.

Am J Physiol Regul Integr Comp Physiol. 2011 Jan;300(1):R12-20. doi: 10.1152/ajpregu.00421.2010. Epub 2010 Oct 13.

20.

Gene expression profiles of Beta-cell enriched tissue obtained by laser capture microdissection from subjects with type 2 diabetes.

Marselli L, Thorne J, Dahiya S, Sgroi DC, Sharma A, Bonner-Weir S, Marchetti P, Weir GC.

PLoS One. 2010 Jul 13;5(7):e11499. doi: 10.1371/journal.pone.0011499.

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