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Altered Mitochondrial Signalling and Metabolism in Cancer.

Chattopadhyay E, Roy B.

Front Oncol. 2017 Mar 20;7:43. doi: 10.3389/fonc.2017.00043. eCollection 2017. Review.


Fatty Acids in Membranes as Homeostatic, Metabolic and Nutritional Biomarkers: Recent Advancements in Analytics and Diagnostics.

Ferreri C, Masi A, Sansone A, Giacometti G, Larocca AV, Menounou G, Scanferlato R, Tortorella S, Rota D, Conti M, Deplano S, Louka M, Maranini AR, Salati A, Sunda V, Chatgilialoglu C.

Diagnostics (Basel). 2016 Dec 22;7(1). pii: E1. doi: 10.3390/diagnostics7010001. Review.


Crystal structure of FabZ-ACP complex reveals a dynamic seesaw-like catalytic mechanism of dehydratase in fatty acid biosynthesis.

Zhang L, Xiao J, Xu J, Fu T, Cao Z, Zhu L, Chen HZ, Shen X, Jiang H, Zhang L.

Cell Res. 2016 Dec;26(12):1330-1344. doi: 10.1038/cr.2016.136. Epub 2016 Nov 22.


Body Mass Index and Metastatic Renal Cell Carcinoma: Clinical and Biological Correlations.

Albiges L, Hakimi AA, Xie W, McKay RR, Simantov R, Lin X, Lee JL, Rini BI, Srinivas S, Bjarnason GA, Ernst S, Wood LA, Vaishamayan UN, Rha SY, Agarwal N, Yuasa T, Pal SK, Bamias A, Zabor EC, Skanderup AJ, Furberg H, Fay AP, de Velasco G, Preston MA, Wilson KM, Cho E, McDermott DF, Signoretti S, Heng DY, Choueiri TK.

J Clin Oncol. 2016 Sep 6. pii: JCO667311. [Epub ahead of print]


MNX1 Is Oncogenically Upregulated in African-American Prostate Cancer.

Zhang L, Wang J, Wang Y, Zhang Y, Castro P, Shao L, Sreekumar A, Putluri N, Guha N, Deepak S, Padmanaban A, Creighton CJ, Ittmann M.

Cancer Res. 2016 Nov 1;76(21):6290-6298. Epub 2016 Aug 30.


Untargeted metabolomics for profiling oncogene-specific metabolic signatures of prostate cancer.

Priolo C, Loda M.

Mol Cell Oncol. 2015 Jan 23;2(4):e1001197. doi: 10.1080/23723556.2014.1001197. eCollection 2015 Oct-Dec.


BAP18 coactivates androgen receptor action and promotes prostate cancer progression.

Sun S, Zhong X, Wang C, Sun H, Wang S, Zhou T, Zou R, Lin L, Sun N, Sun G, Wu Y, Wang B, Song X, Cao L, Zhao Y.

Nucleic Acids Res. 2016 Sep 30;44(17):8112-28. doi: 10.1093/nar/gkw472. Epub 2016 May 25.


Suppression of endogenous lipogenesis induces reversion of the malignant phenotype and normalized differentiation in breast cancer.

Gonzalez-Guerrico AM, Espinoza I, Schroeder B, Park CH, Kvp CM, Khurana A, Corominas-Faja B, Cuyàs E, Alarcón T, Kleer C, Menendez JA, Lupu R.

Oncotarget. 2016 Nov 1;7(44):71151-71168. doi: 10.18632/oncotarget.9463.


A Balanced Tissue Composition Reveals New Metabolic and Gene Expression Markers in Prostate Cancer.

Tessem MB, Bertilsson H, Angelsen A, Bathen TF, Drabløs F, Rye MB.

PLoS One. 2016 Apr 21;11(4):e0153727. doi: 10.1371/journal.pone.0153727. eCollection 2016.


P300 acetyltransferase regulates fatty acid synthase expression, lipid metabolism and prostate cancer growth.

Gang X, Yang Y, Zhong J, Jiang K, Pan Y, Karnes RJ, Zhang J, Xu W, Wang G, Huang H.

Oncotarget. 2016 Mar 22;7(12):15135-49. doi: 10.18632/oncotarget.7715.


Differential requirement for de novo lipogenesis in cholangiocarcinoma and hepatocellular carcinoma of mice and humans.

Li L, Che L, Tharp KM, Park HM, Pilo MG, Cao D, Cigliano A, Latte G, Xu Z, Ribback S, Dombrowski F, Evert M, Gores GJ, Stahl A, Calvisi DF, Chen X.

Hepatology. 2016 Jun;63(6):1900-13. doi: 10.1002/hep.28508. Epub 2016 Mar 25.


Diet-induced alteration of fatty acid synthase in prostate cancer progression.

Huang M, Koizumi A, Narita S, Inoue T, Tsuchiya N, Nakanishi H, Numakura K, Tsuruta H, Saito M, Satoh S, Nanjo H, Sasaki T, Habuchi T.

Oncogenesis. 2016 Feb 15;5:e195. doi: 10.1038/oncsis.2015.42.


[(11)C]acetate PET Imaging is not Always Associated with Increased Lipogenesis in Hepatocellular Carcinoma in Mice.

Li L, Che L, Wang C, Blecha JE, Li X, VanBrocklin HF, Calvisi DF, Puchowicz M, Chen X, Seo Y.

Mol Imaging Biol. 2016 Jun;18(3):360-7. doi: 10.1007/s11307-015-0915-8.


Inactivation of fatty acid synthase impairs hepatocarcinogenesis driven by AKT in mice and humans.

Li L, Pilo GM, Li X, Cigliano A, Latte G, Che L, Joseph C, Mela M, Wang C, Jiang L, Ribback S, Simile MM, Pascale RM, Dombrowski F, Evert M, Semenkovich CF, Chen X, Calvisi DF.

J Hepatol. 2016 Feb;64(2):333-41. doi: 10.1016/j.jhep.2015.10.004. Epub 2015 Oct 22.


Dual fatty acid synthase and HER2 signaling blockade shows marked antitumor activity against breast cancer models resistant to anti-HER2 drugs.

Blancafort A, Giró-Perafita A, Oliveras G, Palomeras S, Turrado C, Campuzano Ò, Carrión-Salip D, Massaguer A, Brugada R, Palafox M, Gómez-Miragaya J, González-Suárez E, Puig T.

PLoS One. 2015 Jun 24;10(6):e0131241. doi: 10.1371/journal.pone.0131241. eCollection 2015.


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