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Items: 1 to 20 of 108

1.

Intracellular trafficking of TREM2 is regulated by presenilin 1.

Zhao Y, Li X, Huang T, Jiang LL, Tan Z, Zhang M, Cheng IH, Wang X, Bu G, Zhang YW, Wang Q, Xu H.

Exp Mol Med. 2017 Dec 1;49(12):e405. doi: 10.1038/emm.2017.200.

2.

Amyloid-beta modulates microglial responses by binding to the triggering receptor expressed on myeloid cells 2 (TREM2).

Zhong L, Wang Z, Wang D, Wang Z, Martens YA, Wu L, Xu Y, Wang K, Li J, Huang R, Can D, Xu H, Bu G, Chen XF.

Mol Neurodegener. 2018 Mar 27;13(1):15. doi: 10.1186/s13024-018-0247-7.

3.

Alzheimer's Disease, Oligomers, and Inflammation.

Forloni G, Balducci C.

J Alzheimers Dis. 2018;62(3):1261-1276. doi: 10.3233/JAD-170819.

4.

Differential Phagocytic Properties of CD45low Microglia and CD45high Brain Mononuclear Phagocytes-Activation and Age-Related Effects.

Rangaraju S, Raza SA, Li NX, Betarbet R, Dammer EB, Duong D, Lah JJ, Seyfried NT, Levey AI.

Front Immunol. 2018 Mar 2;9:405. doi: 10.3389/fimmu.2018.00405. eCollection 2018.

5.

Microglia Gone Rogue: Impacts on Psychiatric Disorders across the Lifespan.

Tay TL, Béchade C, D'Andrea I, St-Pierre MK, Henry MS, Roumier A, Tremblay ME.

Front Mol Neurosci. 2018 Jan 4;10:421. doi: 10.3389/fnmol.2017.00421. eCollection 2017. Review.

6.

Humanized TREM2 mice reveal microglia-intrinsic and -extrinsic effects of R47H polymorphism.

Song WM, Joshita S, Zhou Y, Ulland TK, Gilfillan S, Colonna M.

J Exp Med. 2018 Mar 5;215(3):745-760. doi: 10.1084/jem.20171529. Epub 2018 Jan 10.

PMID:
29321225
7.

Bioenergetic regulation of microglia.

Ghosh S, Castillo E, Frias ES, Swanson RA.

Glia. 2018 Jun;66(6):1200-1212. doi: 10.1002/glia.23271. Epub 2017 Dec 8. Review.

PMID:
29219210
8.

Microglia in Alzheimer's disease.

Hansen DV, Hanson JE, Sheng M.

J Cell Biol. 2018 Feb 5;217(2):459-472. doi: 10.1083/jcb.201709069. Epub 2017 Dec 1. Review.

PMID:
29196460
9.

Microglia-Mediated Neuroprotection, TREM2, and Alzheimer's Disease: Evidence From Optical Imaging.

Condello C, Yuan P, Grutzendler J.

Biol Psychiatry. 2018 Feb 15;83(4):377-387. doi: 10.1016/j.biopsych.2017.10.007. Epub 2017 Oct 14. Review.

10.

Behavioral and transcriptomic analysis of Trem2-null mice: not all knockout mice are created equal.

Kang SS, Kurti A, Baker KE, Liu CC, Colonna M, Ulrich JD, Holtzman DM, Bu G, Fryer JD.

Hum Mol Genet. 2018 Jan 15;27(2):211-223. doi: 10.1093/hmg/ddx366.

11.

TREM2 deficiency exacerbates tau pathology through dysregulated kinase signaling in a mouse model of tauopathy.

Bemiller SM, McCray TJ, Allan K, Formica SV, Xu G, Wilson G, Kokiko-Cochran ON, Crish SD, Lasagna-Reeves CA, Ransohoff RM, Landreth GE, Lamb BT.

Mol Neurodegener. 2017 Oct 16;12(1):74. doi: 10.1186/s13024-017-0216-6.

12.

Microglia in Alzheimer's disease.

Sarlus H, Heneka MT.

J Clin Invest. 2017 Sep 1;127(9):3240-3249. doi: 10.1172/JCI90606. Epub 2017 Sep 1. Review.

13.

TREM2 in Neurodegenerative Diseases.

Jay TR, von Saucken VE, Landreth GE.

Mol Neurodegener. 2017 Aug 2;12(1):56. doi: 10.1186/s13024-017-0197-5. Review.

14.
15.

The Role of Microglia in Retinal Neurodegeneration: Alzheimer's Disease, Parkinson, and Glaucoma.

Ramirez AI, de Hoz R, Salobrar-Garcia E, Salazar JJ, Rojas B, Ajoy D, López-Cuenca I, Rojas P, Triviño A, Ramírez JM.

Front Aging Neurosci. 2017 Jul 6;9:214. doi: 10.3389/fnagi.2017.00214. eCollection 2017. Review.

16.

The Role of Microglia in Prion Diseases: A Paradigm of Functional Diversity.

Obst J, Simon E, Mancuso R, Gomez-Nicola D.

Front Aging Neurosci. 2017 Jun 23;9:207. doi: 10.3389/fnagi.2017.00207. eCollection 2017. Review.

17.

The FTD-like syndrome causing TREM2 T66M mutation impairs microglia function, brain perfusion, and glucose metabolism.

Kleinberger G, Brendel M, Mracsko E, Wefers B, Groeneweg L, Xiang X, Focke C, Deußing M, Suárez-Calvet M, Mazaheri F, Parhizkar S, Pettkus N, Wurst W, Feederle R, Bartenstein P, Mueggler T, Arzberger T, Knuesel I, Rominger A, Haass C.

EMBO J. 2017 Jul 3;36(13):1837-1853. doi: 10.15252/embj.201796516. Epub 2017 May 30.

PMID:
28559417
18.

A split-luciferase complementation, real-time reporting assay enables monitoring of the disease-associated transmembrane protein TREM2 in live cells.

Varnum MM, Clayton KA, Yoshii-Kitahara A, Yonemoto G, Koro L, Ikezu S, Ikezu T.

J Biol Chem. 2017 Jun 23;292(25):10651-10663. doi: 10.1074/jbc.M116.759159. Epub 2017 May 10.

PMID:
28490631
19.

TREM2-Ligand Interactions in Health and Disease.

Kober DL, Brett TJ.

J Mol Biol. 2017 Jun 2;429(11):1607-1629. doi: 10.1016/j.jmb.2017.04.004. Epub 2017 Apr 19. Review.

PMID:
28432014
20.

Tau Spread, Apolipoprotein E, Inflammation, and More: Rapidly Evolving Basic Science in Alzheimer Disease.

Gonzalez B, Abud EM, Abud AM, Poon WW, Gylys KH.

Neurol Clin. 2017 May;35(2):175-190. doi: 10.1016/j.ncl.2017.01.001. Review.

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