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Items: 1 to 20 of 295


The Influence of Extracellular RNA on Cell Behavior in Health, Disease and Regeneration.

Huleihel L, Scarritt ME, Badylak SF.

Curr Pathobiol Rep. 2017 Mar;5(1):13-22. doi: 10.1007/s40139-017-0121-2. Epub 2017 Feb 1.


Impaired endo-lysosomal membrane integrity accelerates the seeding progression of α-synuclein aggregates.

Jiang P, Gan M, Yen SH, McLean PJ, Dickson DW.

Sci Rep. 2017 Aug 9;7(1):7690. doi: 10.1038/s41598-017-08149-w.


Current Understanding of Neurodegenerative Diseases Associated With the Protein Tau.

Josephs KA.

Mayo Clin Proc. 2017 Aug;92(8):1291-1303. doi: 10.1016/j.mayocp.2017.04.016. Review.


The spread of prion-like proteins by lysosomes and tunneling nanotubes: Implications for neurodegenerative diseases.

Victoria GS, Zurzolo C.

J Cell Biol. 2017 Sep 4;216(9):2633-2644. doi: 10.1083/jcb.201701047. Epub 2017 Jul 19. Review.


The Distance between N and C Termini of Tau and of FTDP-17 Mutants Is Modulated by Microtubule Interactions in Living Cells.

Di Primio C, Quercioli V, Siano G, Rovere M, Kovacech B, Novak M, Cattaneo A.

Front Mol Neurosci. 2017 Jun 30;10:210. doi: 10.3389/fnmol.2017.00210. eCollection 2017.


LTP and memory impairment caused by extracellular Aβ and Tau oligomers is APP-dependent.

Puzzo D, Piacentini R, Fá M, Gulisano W, Li Puma DD, Staniszewski A, Zhang H, Tropea MR, Cocco S, Palmeri A, Fraser P, D'Adamio L, Grassi C, Arancio O.

Elife. 2017 Jul 11;6. pii: e26991. doi: 10.7554/eLife.26991.


Glial contributions to neurodegeneration in tauopathies.

Leyns CEG, Holtzman DM.

Mol Neurodegener. 2017 Jun 29;12(1):50. doi: 10.1186/s13024-017-0192-x. Review.


Novel human neuronal tau model exhibiting neurofibrillary tangles and transcellular propagation.

Reilly P, Winston CN, Baron KR, Trejo M, Rockenstein EM, Akers JC, Kfoury N, Diamond M, Masliah E, Rissman RA, Yuan SH.

Neurobiol Dis. 2017 Oct;106:222-234. doi: 10.1016/j.nbd.2017.06.005. Epub 2017 Jun 10.


Propagation of Tau aggregates.

Goedert M, Spillantini MG.

Mol Brain. 2017 May 30;10(1):18. doi: 10.1186/s13041-017-0298-7. Review.


Tau secretion is correlated to an increase of Golgi dynamics.

Mohamed NV, Desjardins A, Leclerc N.

PLoS One. 2017 May 26;12(5):e0178288. doi: 10.1371/journal.pone.0178288. eCollection 2017.


Perivascular AQP4 dysregulation in the hippocampal CA1 area after traumatic brain injury is alleviated by adenosine A2A receptor inactivation.

Zhao ZA, Li P, Ye SY, Ning YL, Wang H, Peng Y, Yang N, Zhao Y, Zhang ZH, Chen JF, Zhou YG.

Sci Rep. 2017 May 22;7(1):2254. doi: 10.1038/s41598-017-02505-6.


Extracellular Tau Oligomers Induce Invasion of Endogenous Tau into the Somatodendritic Compartment and Axonal Transport Dysfunction.

Swanson E, Breckenridge L, McMahon L, Som S, McConnell I, Bloom GS.

J Alzheimers Dis. 2017;58(3):803-820. doi: 10.3233/JAD-170168.


Humanized monoclonal antibody armanezumab specific to N-terminus of pathological tau: characterization and therapeutic potency.

Agadjanyan MG, Zagorski K, Petrushina I, Davtyan H, Kazarian K, Antonenko M, Davis J, Bon C, Blurton-Jones M, Cribbs DH, Ghochikyan A.

Mol Neurodegener. 2017 May 5;12(1):33. doi: 10.1186/s13024-017-0172-1.


A Brief Overview of Tauopathy: Causes, Consequences, and Therapeutic Strategies.

Orr ME, Sullivan AC, Frost B.

Trends Pharmacol Sci. 2017 Jul;38(7):637-648. doi: 10.1016/ Epub 2017 Apr 25. Review.


Roles of tau protein in health and disease.

Guo T, Noble W, Hanger DP.

Acta Neuropathol. 2017 May;133(5):665-704. doi: 10.1007/s00401-017-1707-9. Epub 2017 Apr 6. Review.


Cell-to-cell transfer of SAA1 protein in a cell culture model of systemic AA amyloidosis.

Claus S, Puscalau-Girtu I, Walther P, Syrovets T, Simmet T, Haupt C, Fändrich M.

Sci Rep. 2017 Mar 31;7:45683. doi: 10.1038/srep45683.


Signature of an aggregation-prone conformation of tau.

Eschmann NA, Georgieva ER, Ganguly P, Borbat PP, Rappaport MD, Akdogan Y, Freed JH, Shea JE, Han S.

Sci Rep. 2017 Mar 17;7:44739. doi: 10.1038/srep44739.


Transfer of disrupted-in-schizophrenia 1 aggregates between neuronal-like cells occurs in tunnelling nanotubes and is promoted by dopamine.

Zhu S, Abounit S, Korth C, Zurzolo C.

Open Biol. 2017 Mar;7(3). pii: 160328. doi: 10.1098/rsob.160328.


Spread of tau down neural circuits precedes synapse and neuronal loss in the rTgTauEC mouse model of early Alzheimer's disease.

Pickett EK, Henstridge CM, Allison E, Pitstick R, Pooler A, Wegmann S, Carlson G, Hyman BT, Spires-Jones TL.

Synapse. 2017 Jun;71(6). doi: 10.1002/syn.21965. Epub 2017 Mar 6.


Therapeutic Strategies for Restoring Tau Homeostasis.

Young ZT, Mok SA, Gestwicki JE.

Cold Spring Harb Perspect Med. 2017 Feb 3. pii: a024612. doi: 10.1101/cshperspect.a024612. [Epub ahead of print]


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