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Items: 18


Cytoskeletal Regulation of Inflammation and Its Impact on Skin Blistering Disease Epidermolysis Bullosa Acquisita.

Kopecki Z, Ludwig RJ, Cowin AJ.

Int J Mol Sci. 2016 Jul 13;17(7). pii: E1116. doi: 10.3390/ijms17071116. Review.


Cytoskeletal protein Flightless I inhibits apoptosis, enhances tumor cell invasion and promotes cutaneous squamous cell carcinoma progression.

Kopecki Z, Yang GN, Jackson JE, Melville EL, Calley MP, Murrell DF, Darby IA, O'Toole EA, Samuel MS, Cowin AJ.

Oncotarget. 2015 Nov 3;6(34):36426-40. doi: 10.18632/oncotarget.5536.


Controlling the origins of inflammation with a photoactive lipopeptide immunopotentiator.

Mancini RJ, Stutts L, Moore T, Esser-Kahn AP.

Angew Chem Int Ed Engl. 2015 May 11;54(20):5962-5. doi: 10.1002/anie.201500416. Epub 2015 Mar 20.


Integrating phosphoproteome and transcriptome reveals new determinants of macrophage multinucleation.

Rotival M, Ko JH, Srivastava PK, Kerloc'h A, Montoya A, Mauro C, Faull P, Cutillas PR, Petretto E, Behmoaras J.

Mol Cell Proteomics. 2015 Mar;14(3):484-98. doi: 10.1074/mcp.M114.043836. Epub 2014 Dec 22.


Toward a comprehensive map of the effectors of rab GTPases.

Gillingham AK, Sinka R, Torres IL, Lilley KS, Munro S.

Dev Cell. 2014 Nov 10;31(3):358-73. doi: 10.1016/j.devcel.2014.10.007. Epub 2014 Nov 10.


Noncoding RNAs and LRRFIP1 regulate TNF expression.

Shi L, Song L, Fitzgerald M, Maurer K, Bagashev A, Sullivan KE.

J Immunol. 2014 Apr 1;192(7):3057-67. doi: 10.4049/jimmunol.1302063. Epub 2014 Feb 24.


LRRFIP2 negatively regulates NLRP3 inflammasome activation in macrophages by promoting Flightless-I-mediated caspase-1 inhibition.

Jin J, Yu Q, Han C, Hu X, Xu S, Wang Q, Wang J, Li N, Cao X.

Nat Commun. 2013;4:2075. doi: 10.1038/ncomms3075.


The influence of Flightless I on Toll-like-receptor-mediated inflammation in a murine model of diabetic wound healing.

Ruzehaji N, Mills SJ, Melville E, Arkell R, Fitridge R, Cowin AJ.

Biomed Res Int. 2013;2013:389792. doi: 10.1155/2013/389792. Epub 2013 Feb 18.


Identification and function of leucine-rich repeat flightless-I-interacting protein 2 (LRRFIP2) in Litopenaeus vannamei.

Zhang S, Yan H, Li CZ, Chen YH, Yuan FH, Chen YG, Weng SP, He JG.

PLoS One. 2013;8(2):e57456. doi: 10.1371/journal.pone.0057456. Epub 2013 Feb 28.


Protein phosphatase 2A catalytic subunit α plays a MyD88-dependent, central role in the gene-specific regulation of endotoxin tolerance.

Xie L, Liu C, Wang L, Gunawardena HP, Yu Y, Du R, Taxman DJ, Dai P, Yan Z, Yu J, Holly SP, Parise LV, Wan YY, Ting JP, Chen X.

Cell Rep. 2013 Mar 28;3(3):678-88. doi: 10.1016/j.celrep.2013.01.029. Epub 2013 Feb 21.


Lysosomal secretion of Flightless I upon injury has the potential to alter inflammation.

Cowin AJ, Lei N, Franken L, Ruzehaji N, Offenhäuser C, Kopecki Z, Murray RZ.

Commun Integr Biol. 2012 Nov 1;5(6):546-9. doi: 10.4161/cib.21928.


Regulation of TLR7/9 signaling in plasmacytoid dendritic cells.

Bao M, Liu YJ.

Protein Cell. 2013 Jan;4(1):40-52. doi: 10.1007/s13238-012-2104-8. Epub 2012 Nov 7. Review.


A major locus on chromosome 3p22 conferring predisposition to human herpesvirus 8 infection.

Pedergnana V, Gessain A, Tortevoye P, Byun M, Bacq-Daian D, Boland A, Casanova JL, Abel L, Plancoulaine S.

Eur J Hum Genet. 2012 Jun;20(6):690-5. doi: 10.1038/ejhg.2011.260. Epub 2012 Jan 18.


Engagement of TLR2 reverses the suppressor function of conjunctiva CD4+CD25+ regulatory T cells and promotes herpes simplex virus epitope-specific CD4+CD25- effector T cell responses.

Dasgupta G, Chentoufi AA, You S, Falatoonzadeh P, Urbano LA, Akhtarmalik A, Nguyen K, Ablabutyan L, Nesburn AB, BenMohamed L.

Invest Ophthalmol Vis Sci. 2011 May 17;52(6):3321-33. doi: 10.1167/iovs.10-6522.


Unambiguous characterization of site-specific phosphorylation of leucine-rich repeat Fli-I-interacting protein 2 (LRRFIP2) in Toll-like receptor 4 (TLR4)-mediated signaling.

Gunawardena HP, Huang Y, Kenjale R, Wang H, Xie L, Chen X.

J Biol Chem. 2011 Apr 1;286(13):10897-910. doi: 10.1074/jbc.M110.168179. Epub 2011 Jan 10.


Leucine-rich repeat (in Flightless I) interacting protein-1 regulates a rapid type I interferon response.

Bagashev A, Fitzgerald MC, Larosa DF, Rose PP, Cherry S, Johnson AC, Sullivan KE.

J Interferon Cytokine Res. 2010 Nov;30(11):843-52. doi: 10.1089/jir.2010.0017. Epub 2010 Jun 29.


Dominant role of the MyD88-dependent signaling pathway in mediating early endotoxin-induced murine ileus.

Buchholz BM, Billiar TR, Bauer AJ.

Am J Physiol Gastrointest Liver Physiol. 2010 Aug;299(2):G531-8. doi: 10.1152/ajpgi.00060.2010. Epub 2010 May 27.

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